Cited by 50Selenium in Biological SystemsSeaweed-derived Bioactive CompoundsOrganoselenium and organotellurium chemistry

In vitro bioaccessibility of selenoamino acids from selenium (Se)-enriched Chlorella vulgaris biomass in comparison to selenized yeast; a Se-enriched food supplement; and Se-rich foods

Vu, Dai Long, Saurav, Kumar, Mylenko, Mykola, Ranglová, Karolína, Kuta, Jan, Ewe, Daniela, Masojídek, Jiří, Hrouzek, Pavel·2019·Food Chemistry

Abstract

Selenium (Se) is an indispensable microelement in our diet and health issues resulting from deficiencies are well documented. Se-containing food supplements are available on the market including Se-enriched Chlorella vulgaris (Se-Chlorella) which accumulates Se in the form of Se-amino acids (Se-AAs). Despite its popular uses, data about the bioaccessibility of Se-AAs from Se-Chlorella are completely missing. In the present study, gastrointestinal digestion times were optimized and the in vitro bioaccessibility of Se-AAs in Se-Chlorella, Se-yeast, a commercially available Se-enriched food supplement (Se-supplement) and Se rich foods (Se-foods) were compared. Higher bioaccessibility was found in Se-Chlorella (∼49%) as compared to Se-yeast (∼21%), Se-supplement (∼32%) and Se-foods. The methods used in production of Se-Chlorella biomass were also investigated. We found that disintegration increased bioaccessibility whereas the drying process had no effect. Similarly, temperature treatment by microwave oven also increased bioaccessibility whereas boiling water did not.

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Crossref · 10.1016/j.foodchem.2018.12.004

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  • Chlorella application is especially intended for the sector of dietary supplements, nutraceuticals, and pharmaceutical formulations.

    “Its application is especially intended for the sector of dietary supplements, nutraceuticals, and pharmaceutical formulations (Saurav et al., 2019; Yuan et al., 2020; Sinetova et al., 2024).”

    From Microalgae biotechnology and its role in sustainable and healthy food design (2025) · cites this paper as Saurav et al., 2019

  • Chlorella sp. is recognized by the Food and Agriculture Organization (FAO) as a "healthy green food".

    “Chlorella sp., in turn, is recognized by the Food and Agriculture Organization (FAO) as a “healthy green food””

    From Microalgae biotechnology and its role in sustainable and healthy food design (2025) · cites this paper as Saurav et al., 2019

  • Chlorella sp. has been consolidated as one of the most widely produced microalgae on a large scale in Europe, Asia, and the United States.

    “and has been consolidated as one of the most widely produced microalgae on a large scale in Europe, Asia, and the United States.”

    From Microalgae biotechnology and its role in sustainable and healthy food design (2025) · cites this paper as Saurav et al., 2019

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Authors
Vu, D. L., Saurav, K., Mylenko, M., Ranglová, K., Kuta, J., Ewe, D., Masojídek, J., & Hrouzek, P.
Affiliations
  • Czech Academy of Sciences, Institute of Microbiology (CZ)
  • Masaryk University (CZ)
Corresponding author
  • Vu, Dai Long
  • Hrouzek, Pavel
Venue
Food Chemistry
Publisher
Elsevier BV
Published
2019-05
Volume
279
Pages
12-19
ISSN
0308-8146 (ISSN-L)
OpenAlex
W2902704113
Cited by
50
References
40
Citations by year
2026: 5 · 2025: 8 · 2024: 8 · 2023: 8 · 2022: 6 · 2021: 9 · 2020: 5 · 2019: 1
FWCI
3.10
Type
journal article
Language
en
Open access
closed
Locations
  • Food Chemistry (publishedVersion)
  • PubMed (publishedVersion)
Funders
Ministerstvo Školství, Mládeže a Tělovýchovy (CZ.02.1.01/0.0/0.0/16_013/0001761, CZ.1.05/2.1.00/19.0392, LM2015051, LM2015055, LO1416)
Topics
  • Health Sciences › Nursing › Nutrition and Dietetics › Selenium in Biological Systems
  • Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Organoselenium and organotellurium chemistry
Keywords
selenoamino acids, selenium yeast, selenium-rich foods, gastrointestinal digestion, microwave treatment, drying effects, selenium accumulation
MeSH terms
Chromatography, High Pressure Liquid, Food, Fortified, Gas Chromatography-Mass Spectrometry, Saccharomyces cerevisiae, Selenium, Selenomethionine, Mass Spectrometry, Temperature, Selenocysteine, Biomass, Dietary Supplements, Chlorella vulgaris, Limit of Detection

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