The DOI matches its Crossref record; 83 of the 83 references it cites were found in a registry or an index.
Tomato and lycopene and multiple health outcomes: Umbrella review
Abstract
Lycopene is a potent lipophilic antioxidant in tomato. We aim to clarify the evidence for associations between tomato and lycopene and multiple health outcomes. Umbrella review of meta-analyses and systematic reviews was performed in humans. A total of 174 articles were searched, 17 articles with 20 health outcomes were identified by eligibility criteria. Tomato intake was inversely associated with all-cause mortality, coronary heart disease mortality, cerebrovascular disease mortality, prostate cancer, and gastric cancer. Dietary lycopene intake or serum lycopene was inversely associated with all-cause mortality, prostate cancer, stroke, cardiovascular disease, metabolic syndrome, and male infertility. Caution was warranted for potential allergy and pollution. The quality of the vast majority of evidence by GRADE was low or very low with the remaining six as moderate. The intake of tomato or lycopene was generally safe and beneficial for multiple health outcomes in humans. But the quality of the evidence was not high.
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Bias in meta-analysis detected by a simple, graphical test
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GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
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GRADE guidelines: 1. Introduction—GRADE evidence profiles and summary of findings tables
Guyatt, G., Oxman, A. D., Akl, E. A., Kunz, R., Vist, G., Brozek, J., Norris, S., Falck-Ytter, Y., Glasziou, P., & deBeer, H. (2011) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2010.04.026 · Cited by 10,681
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Development of AMSTAR: A measurement tool to assess the methodological quality of systematic reviews
Shea, B. J., Grimshaw, J. M., Wells, G. A., Boers, M., Andersson, N., Hamel, C., Porter, A. C., Tugwell, P., Moher, D., & Bouter, L. M. (2007) · BMC Medical Research Methodology · doi:10.1186/1471-2288-7-10 · Cited by 4,374
The tomato genome sequence provides insights into fleshy fruit evolution
The Tomato Genome Consortium (2012) · Nature · doi:10.1038/nature11119 · Cited by 3,289
What is ‘quality of evidence’ and why is it important to clinicians?
Guyatt, G. H., Oxman, A. D., Kunz, R., Vist, G. E., Falck-Ytter, Y., & Schünemann, H. J. (2008) · BMJ · doi:10.1136/bmj.39490.551019.be · Cited by 3,250
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A Prospective Study of Tomato Products, Lycopene, and Prostate Cancer Risk
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Coffee consumption and health: umbrella review of meta-analyses of multiple health outcomes
Poole, R., Kennedy, O. J., Roderick, P., Fallowfield, J. A., Hayes, P. C., & Parkes, J. (2017) · BMJ · doi:10.1136/bmj.j5024 · Cited by 835
Cited by
2022 Update on Prostate Cancer Epidemiology and Risk Factors—A Systematic Review
Bergengren, O., Pekala, K. R., Matsoukas, K., Fainberg, J., Mungovan, S. F., Bratt, O., Bray, F., Brawley, O., Luckenbaugh, A. N., Mucci, L., et al. (2023) · European Urology · doi:10.1016/j.eururo.2023.04.021 · Cited by 848
Lycopene: Food Sources, Biological Activities, and Human Health Benefits
Khan, U. M., Sevindik, M., Zarrabi, A., Nami, M., Ozdemir, B., Kaplan, D. N., Selamoglu, Z., Hasan, M., Kumar, M., Alshehri, M. M., et al. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/2713511 · Cited by 346
Saini, R. K., Prasad, P., Lokesh, V., Shang, X., Shin, J., Keum, Y.-S., & Lee, J.-H. (2022) · Antioxidants · doi:10.3390/antiox11040795 · Cited by 285
Metadata
- Authors
- Li, N., Wu, X., Zhuang, W., Xia, L., Chen, Y., Wu, C., Rao, Z., Du, L., Zhao, R., Yi, M., Wan, Q., & Zhou, Y.
- Venue
- Food Chemistry
- Publisher
- Elsevier BV
- Published
- 2021-05
- Volume
- 343
- Pages
- 128396
- ISSN
- 0308-8146 (ISSN-L)
- OpenAlex
- W3096351688
- Cited by
- 265
- References
- 83
- FWCI
- 12.22
- Type
- journal article
- Language
- en
- Open access
- closed
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- Li, N., Wu, X., Zhuang, W., Xia, L., Chen, Y., Wu, C., Rao, Z., Du, L., Zhao, R., Yi, M., Wan, Q., & Zhou, Y. (2021). Tomato and lycopene and multiple health outcomes: Umbrella review. Food Chemistry. https://doi.org/10.1016/j.foodchem.2020.128396
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