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In vitro antioxidant, anti-diabetic, cholinesterase and tyrosinase inhibitory potential of fresh juice from Citrus hystrix and C. maxima fruits
Open accessAbstract
In the present study, antioxidant potential, α-amylase, α-glucosidase, cholinesterase and tyrosinase inhibitory activity of fresh juice from indigenous fruits of Citrus hystrix and C. maxima (Red & White var.) were investigated using an in vitro model. The contents of total phenolics, tannins, and total flavonoids ranged between 836.90 and 909.52 mg gallic acid equivalent (GAE)/L, 333.33 and 523.21 mg gallic acid equivalent (GAE)/L and 224.88 and 262.22 mg rutin equivalent/L, respectively. The antioxidant activity of fresh juice was evaluated by employing different in vitro assays such as reducing power assay, DPPH, ABTS+ and OH radical scavenging capacities, peroxidation inhibition activity, antihemolytic assay. In addition, 75.55%–79.75% of α-amylase and 70.68%–72.83% of α-glucosidase enzyme inhibition characteristics were found under in vitro starch digestion bioassay. Also, all the juice samples exhibited excellent tyrosinase (76.95%–80.79%), acetylcholinesterase (75.71%–79.74%) and β-glucuronidase inhibitory activity (68.13%–69.38%). These results indicated that fresh juice of C. hystrix and C. maxima (Red & White var.) could be used as a source of antioxidant agents, functional food and nutraceuticals.
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Cited by
Adefegha, S. A., Oyeleye, S. I., & Oboh, G. (2015) · Biochemistry Research International · doi:10.1155/2015/347673 · Cited by 86
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Agu, K. C., Eluehike, N., Ofeimun, R. O., Abile, D., Ideho, G., Ogedengbe, M. O., Onose, P. O., & Elekofehinti, O. O. (2019) · Clinical Phytoscience · doi:10.1186/s40816-019-0116-0 · Cited by 53
Ratanachamnong, P., Chunchaowarit, Y., Namchaiw, P., Niwaspragrit, C., Rattanacheeworn, P., & Jaisin, Y. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e13068 · Cited by 11
Metadata
- Authors
- Abirami, A., Nagarani, G., & Siddhuraju, P.
- Venue
- Food Science and Human Wellness
- Publisher
- Tsinghua University Press
- Published
- 2014-03
- Volume
- 3
- Issue
- 1
- Pages
- 16-25
- ISSN
- 2097-0765 (ISSN-L)
- 2213-4530
- OpenAlex
- W2138389902
- Cited by
- 175
- References
- 0
- FWCI
- 7.18
- Type
- journal article
- Language
- en
- Open access
- diamond
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- Abirami, A., Nagarani, G., & Siddhuraju, P. (2014). In vitro antioxidant, anti-diabetic, cholinesterase and tyrosinase inhibitory potential of fresh juice from Citrus hystrix and C. maxima fruits. Food Science and Human Wellness. https://doi.org/10.1016/j.fshw.2014.02.001
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