Cited by 130Developmental Biology and Gene RegulationNonlinear Dynamics and Pattern FormationMathematical Biology Tumor Growth

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Turing patterns in development: what about the horse part?

Marcon, Luciano, Sharpe, James·2012·Current Opinion in Genetics & Development

Abstract

For many years Turing patterns-the repetitive patterns which Alan Turing proved could arise from simple diffusing and interacting factors-have remained an interesting theoretical possibility, rather than a central concern of the developmental biology community. Recently however, this has started to change, with an increasing number of studies combining both experimental and theoretical work to reveal how Turing models may underlie a variety of patterning or morphogenetic processes. We review here the recent developments in this field across a wide range of model systems.

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Crossref · 10.1016/j.gde.2012.11.013

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Research works printed but not linked: 37

  1. Wolpert, 1969, Positional information and the spatial pattern of cellular differentiation, J Theor Biol, 25, 1, 10.1016/S0022-5193(69)80016-0 · DOI
  2. Turing, 1952, The chemical basis of morphogenesis, Phil Trans R Soc Lond B: Biol Sci, 641, 37
  3. Akam, 1989, Drosophila development: making stripes inelegantly, Nature, 341, 282, 10.1038/341282a0 · DOI
  4. Hogeweg, 2011, The roots of bioinformatics in theoretical biology, PLoS Comput Biol, 7, e1002021, 10.1371/journal.pcbi.1002021 · DOI
  5. Solnica-Krezel, 2003, Vertebrate development: taming the nodal waves, Curr Biol, 13, R7, 10.1016/S0960-9822(02)01378-7 · DOI
  6. Nakamura, 2006, Generation of robust left-right asymmetry in the mouse embryo requires a self-enhancement and lateral-inhibition system, Dev Cell, 11, 495, 10.1016/j.devcel.2006.08.002 · DOI
  7. Hamada, 2012, In search of Turing in vivo: understanding Nodal and Lefty behavior, Dev Cell, 22, 911, 10.1016/j.devcel.2012.05.003 · DOI
  8. Shen, 2007, Nodal signaling: developmental roles and regulation, Development, 134, 1023, 10.1242/dev.000166 · DOI
  9. Chen, 2002, Lefty proteins are long-range inhibitors of squint-mediated nodal signaling, Curr Biol, 12, 2124, 10.1016/S0960-9822(02)01362-3 · DOI
  10. Hamada, 2002, Establishment of vertebrate left-right asymmetry, Nat Rev Genet, 3, 103, 10.1038/nrg732 · DOI · Paper page
  11. Saijoh, 2000, Left-right asymmetric expression of lefty2 and nodal is induced by a signaling pathway that includes the transcription factor FAST2, Mol Cell, 5, 35, 10.1016/S1097-2765(00)80401-3 · DOI
  12. Muller, 2012, Differential diffusivity of Nodal and Lefty underlies a reaction–diffusion patterning system, Science, 336, 721, 10.1126/science.1221920 · DOI
  13. Oki, 2007, Sulfated glycosaminoglycans are necessary for Nodal signal transmission from the node to the left lateral plate in the mouse embryo, Development, 134, 3893, 10.1242/dev.009464 · DOI
  14. Marjoram, 2011, Rapid differential transport of Nodal and Lefty on sulfated proteoglycan-rich extracellular matrix regulates left-right asymmetry in Xenopus, Development, 138, 475, 10.1242/dev.056010 · DOI
  15. Jung, 1998, Local inhibitory action of BMPs and their relationships with activators in feather formation: implications for periodic patterning, Dev Biol, 196, 11, 10.1006/dbio.1998.8850 · DOI
  16. Michon, 2008, BMP2 and BMP7 play antagonistic roles in feather induction, Development, 135, 2797, 10.1242/dev.018341 · DOI
  17. Beites, 2009, Follistatin modulates a BMP autoregulatory loop to control the size and patterning of sensory domains in the developing tongue, Development, 136, 2187, 10.1242/dev.030544 · DOI
  18. Mou, 2011, Cryptic patterning of avian skin confers a developmental facility for loss of neck feathering, PLoS Biol, 9, e1001028, 10.1371/journal.pbio.1001028 · DOI
  19. Painter, 2012, Towards an integrated experimental–theoretical approach for assessing the mechanistic basis of hair and feather morphogenesis, Interface Focus, 2, 433, 10.1098/rsfs.2011.0122 · DOI
  20. Nagorcka, 1985, The role of a reaction–diffusion system in the initiation of primary hair follicles, J Theor Biol, 114, 243, 10.1016/S0022-5193(85)80106-5 · DOI
  21. Nagorcka, 1983, Evidence for a reaction–diffusion system as a mechanism controlling mammalian hair growth, Biosystems, 16, 323, 10.1016/0303-2647(83)90015-1 · DOI
  22. Sick, 2006, WNT and DKK determine hair follicle spacing through a reaction–diffusion mechanism, Science, 314, 1447, 10.1126/science.1130088 · DOI · Paper page
  23. Headon, 2009, Stippling the skin: generation of anatomical periodicity by reaction–diffusion mechanisms, Math Model Nat Phenom, 4, 83, 10.1051/mmnp/20094402 · DOI
  24. Mou, 2006, Generation of the primary hair follicle pattern, Proc Natl Acad Sci U S A, 103, 9075, 10.1073/pnas.0600825103 · DOI · Paper page
  25. Klika, 2011, The influence of receptor-mediated interactions on reaction–diffusion mechanisms of cellular self-organisation, Bull Math Biol, 74, 935, 10.1007/s11538-011-9699-4 · DOI
  26. Kondo, 1995, A reaction–diffusion wave on the skin of the marie angelfish Pomacanthus, Nature, 376, 765, 10.1038/376765a0 · DOI
  27. Eom, 2012, Melanophore migration and survival during zebrafish adult pigment stripe development require the immunoglobulin superfamily adhesion molecule Igsf11, PLoS Genet, 8, e1002899, 10.1371/journal.pgen.1002899 · DOI · Paper page
  28. Gierer, 1972, A theory of biological pattern formation, Kybernetik, 12, 30, 10.1007/BF00289234 · DOI · Paper page
  29. Inaba, 2012, Pigment pattern formation by contact-dependent depolarization, Science, 335, 677, 10.1126/science.1212821 · DOI · Paper page
  30. Watanabe, 2006, Spot pattern of leopard Danio is caused by mutation in the zebrafish connexin41.8 gene, EMBO Rep, 7, 893, 10.1038/sj.embor.7400757 · DOI · Paper page
  31. Watanabe, 2012, Changing clothes easily: connexin41.8 regulates skin pattern variation, Pigment Cell Melanoma Res, 25, 326, 10.1111/j.1755-148X.2012.00984.x · DOI
  32. Miura, 2002, Depletion of FGF acts as a lateral inhibitory factor in lung branching morphogenesis in vitro, Mech Dev, 116, 29, 10.1016/S0925-4773(02)00132-6 · DOI
  33. Menshykau, 2012, Branch mode selection during early lung development, PLoS Comput Biol, 8, e1002377, 10.1371/journal.pcbi.1002377 · DOI
  34. Economou, 2012, Periodic stripe formation by a Turing mechanism operating at growth zones in the mammalian palate, Nat Genet, 44, 348, 10.1038/ng.1090 · DOI
  35. Newman, 1979, Dynamics of skeletal pattern formation in developing chick limb, Science, 205, 662, 10.1126/science.462174 · DOI
  36. Sheth R, Marcon L, Felix Bastida M, Junco M, Quintana L, Dahn R, Kmita M, Sharpe J, Ros MA: Hox genes regulate digit patterning by controlling the wavelength of a Turing-type mechanism. Science 2012, in press. · DOI
  37. Miura, 2000, TGFbeta2 acts as an “activator” molecule in reaction–diffusion model and is involved in cell sorting phenomenon in mouse limb micromass culture, Dev Dyn, 217, 241, 10.1002/(SICI)1097-0177(200003)217:3<241::AID-DVDY2>3.0.CO;2-K · DOI

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Metadata

Authors
Marcon, L., & Sharpe, J.
Affiliations
  • Universitat Pompeu Fabra (ES)
  • Institució Catalana de Recerca i Estudis Avançats (ES)
Corresponding author
Sharpe, James
Venue
Current Opinion in Genetics & Development
Publisher
Elsevier BV
Published
2012-12
Volume
22
Issue
6
Pages
578-584
ISSN
0959-437X (ISSN-L)
OpenAlex
W2057669106
Cited by
130
References
0
Citations by year
2026: 13 · 2025: 16 · 2024: 12 · 2023: 9 · 2022: 8 · 2021: 14 · 2020: 15 · 2019: 6 · 2018: 15 · 2017: 5 · 2016: 6 · 2015: 6 · 2014: 4 · 2013: 1
FWCI
0.32
Type
journal article
Language
en
Open access
closed
Locations
  • Current Opinion in Genetics & Development (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
  • Physical Sciences › Physics and Astronomy › Statistical and Nonlinear Physics › Nonlinear Dynamics and Pattern Formation
  • Physical Sciences › Mathematics › Modeling and Simulation › Mathematical Biology Tumor Growth
Keywords
Turing patterns, reaction-diffusion, morphogenesis, developmental patterning, pattern formation, model organisms
MeSH terms
Animals, Feathers, Lung, Models, Biological, Palate, Skin, Hair Follicle, Body Patterning

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