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Cited by 355Diabetes Management and EducationCardiac Health and Mental HealthMental Health Treatment and Access

The DOI matches its Crossref record; 68 of the 69 references it cites were found in a registry or an index.

Depression and risk of mortality in individuals with diabetes: a meta-analysis and systematic review

Open access
Park, Mijung, Katon, Wayne J., Wolf, Fredric M.·2013·General Hospital Psychiatry
DOI 10.1016/j.genhosppsych.2013.01.006PMC PMC3644308
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Abstract

OBJECTIVES: To estimate risk of comorbid depression on all-cause mortality over time among individuals with diabetes. METHODS: The Medline, Cumulative Index to Nursing and Allied Health Literature, Cochrane Library, Embase and Science Direct databases were searched through September 30, 2012. We limited our search to longitudinal or prospective studies reporting all-cause mortality among those having depression and diabetes, compared with those having diabetes alone that used hazard ratios (HRs) as the main outcome. Two reviewers independently extracted primary data and evaluated the quality of studies using predetermined criteria. The pooled random effects adjusted HRs were estimated using meta-analysis. The impact of moderator variables on study effect size was examined with meta-regression. RESULTS: A total of 42,363 respondents from 10 studies were included in the analysis. Depression was significantly associated with risk of mortality (pooled HR=1.50, 95% confidence interval=1.35-1.66). Little evidence for heterogeneity was found across the studies (Cochran Q=13.52, P=.20, I(2)=26.03). No significant possibility of publication bias was detected (Egger's regression intercept=0.98, P=.23). CONCLUSION: Depression significantly increases the risk of mortality among individuals with diabetes. Early detection and treatment of depression may improve health outcomes in this population.

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Metadata

Authors
Park, M., Katon, W. J., & Wolf, F. M.
Affiliations
  • University of Pittsburgh (US)
  • University of Washington (US)
Corresponding author
Park, Mijung
ORCID
Park, Mijung
Venue
General Hospital Psychiatry
Publisher
Elsevier BV
Published
2013-05
Volume
35
Issue
3
Pages
217-225
ISSN
0163-8343 (ISSN-L)
DOI
10.1016/j.genhosppsych.2013.01.006
PMC
PMC3644308
OpenAlex
W2109708655
Cited by
355
References
69
Citations by year
2026: 13 · 2025: 17 · 2024: 25 · 2023: 28 · 2022: 37 · 2021: 20 · 2020: 32 · 2019: 27 · 2018: 26 · 2017: 27 · 2016: 38 · 2015: 21 · 2014: 30 · 2013: 14
FWCI
5.11
Type
journal article
Language
en
Open access
Licence
Locations
  • General Hospital Psychiatry (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
  • eScholarship (California Digital Library) (submittedVersion)
Funders
  • University of Washington
  • National Institute of Mental Health (MH069471, K24MH069471, NIMH K24, T32MH073553, 2 T32 MH 37553-6)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
  • Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
Keywords
depression, diabetes mellitus, all-cause mortality, comorbidities, depression screening, depression treatment, cardiovascular risk
MeSH terms
Depressive Disorder, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Humans, Risk Factors, Comorbidity

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