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Cited by 21Stroke Rehabilitation and RecoveryCardiac Health and Mental HealthAcute Ischemic Stroke Management

The association between the severity of poststroke depression and clinical outcomes after first-onset stroke in Korean patients

Park, Geun-Young, Im, Sun, Oh, Chang Hoon, Lee, Soo-Jung, Pae, Chi-Un·2015·General Hospital Psychiatry
DOI 10.1016/j.genhosppsych.2015.02.009
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Abstract

Objective The purpose of the present study is to evaluate the association between poststroke depression (PSD) and clinical outcomes in first-onset stroke patients who are undergoing a rehabilitation program.Methods The present study included 180 inpatients that were recruited consecutively and followed up over a 6-month observational period. Poststroke depression was diagnosed using the criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Symptoms of depression and clinical outcomes were assessed using the Beck Depression Inventory, the modified Barthel Index (MBI) and the Mini Mental State Examination (MMSE). All patients were assessed at baseline and at the end of the 6-month observational period.Results Of the 180 patients, 127 (70.6%) were diagnosed with minimal-to-mild depression (MMD), and 53 (29.4%) were diagnosed with moderate-to-severe depression (MSD). The mean change in MBI scores from baseline to 6 months was significantly higher (P=.029) in the MMD group (23.8) than in the MSD group (8.6). The odds ratio for an unfavorable outcome (MBI score <60) in patients with MSD was approximately 3.5 in relation to patients with MMD. The mean change in MMSE score (4.4 versus 7.4) was not significantly different between the MMD and MSD groups.Conclusion The present findings suggest that the severity of PSD may be associated with clinical outcomes in Korean patients 6 months after a first-onset stroke. Our data agree with previous findings, which indicate that clinicians should carefully evaluate symptoms of depression in stroke patients during routine clinical practice. The methodological shortcomings of the present study may require further studies with adequate power and improved design to clarify the association between PSD and clinical outcomes following stroke.

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Authors
Park, G.-Y., Im, S., Oh, C. H., Lee, S.-J., & Pae, C.-U.
Affiliations
  • Catholic University of Korea (KR)
  • Duke University (US)
Corresponding author
Pae, Chi-Un
ORCID
Venue
General Hospital Psychiatry
Publisher
Elsevier BV
Published
2015-05
Volume
37
Issue
3
Pages
245-250
ISSN
0163-8343 (ISSN-L)
DOI
10.1016/j.genhosppsych.2015.02.009
OpenAlex
W1967868414
Cited by
21
References
31
Citations by year
2024: 1 · 2023: 2 · 2022: 2 · 2020: 1 · 2019: 3 · 2018: 5 · 2017: 3 · 2016: 2 · 2015: 2
FWCI
4.03
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • General Hospital Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
Funders
Korean Health Technology R&D Project, Ministry of Health & Welfare, Republic of Korea (HI12C0003)
Topics
  • Health Sciences › Medicine › Rehabilitation › Stroke Rehabilitation and Recovery
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
  • Health Sciences › Medicine › Epidemiology › Acute Ischemic Stroke Management
Keywords
post-stroke depression, depression severity, stroke rehabilitation, functional outcome, activities of daily living, cognitive function, Korean patients
MeSH terms
Stroke Rehabilitation, Aged, Depression, Major Depressive Disorder, Female, Follow-Up Studies, Humans, Male, Middle Aged, Severity of Illness Index, Outcome Assessment, Health Care, Stroke, Republic of Korea

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