Cited by 345Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesMental Health Treatment and AccessTreatment of Major Depression

Performance of the Japanese version of the Patient Health Questionnaire-9 (J-PHQ-9) for depression in primary care

Muramatsu, Kumiko, Miyaoka, Hitoshi, Kamijima, Kunitoshi, Muramatsu, Yoshiyuki, Tanaka, Yutaka, Hosaka, Michio, Miwa, Yusuke, Fuse, Katsuya +5 more·2018·General Hospital Psychiatry

Abstract

Objective To assess the performance of the Japanese version of the Patient Health Questionnaire-9 (J-PHQ-9) for depression in primary care.Methods Participants in both phases completed the J-PHQ-9, while patients in the second phase also completed the SF-8 (the short form for the health-related QOL scale SF-36). Subjects (n = 284; male = 107, female = 177) had to return the questionnaires to their health care professional within 48 hours and undergo a diagnostic evaluation interview based on the Japanese version of M.I.N.I-Plus.Results 93 patients were diagnosed as having major depressive disorder (MDD). In the J-PHQ-9, the optimal cutpoint ≥ 10 had sensitivity of 90.5% and specificity of 76.6%. As for the categorical algorithms, the sensitivity was 80.6%; specificity was 89.5%, and a positive likelihood ratio of 7.7. The Stratum-specific likelihood ratios (SSLRs) of the J-PHQ-9 scores of 0-9, 10-14, 15-19, and 20-27 for major depression were 0.10 (95% CI: 0.05-0.20), 1.67 (95% CI: 1.02-2.76), 5.41 (95% CI: 2.87-10.22), and 11.98 (95% CI: 5.39-26.63), respectively. The relationship between the severity of J-PHQ-9 and the MCS of SF-8 was significant (χ 2 = 85.72, df = 4, P ≤ 0.0001).Conclusions This study has validated the J-PHQ-9 as a useful tool for the assessment of MDD in primary care in Japan.

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Crossref · 10.1016/j.genhosppsych.2018.03.007

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  • The PHQ-9 is a self-administered tool for screening the severity of depression during the prior 2 weeks.

    “The PHQ‐9 is self‐administered tool for screening. It examines the severity of depression during the prior 2 weeks and is described elsewhere.”

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Authors
Muramatsu, K., Miyaoka, H., Kamijima, K., Muramatsu, Y., Tanaka, Y., Hosaka, M., Miwa, Y., Fuse, K., Yoshimine, F., Mashima, I., Shimizu, N., Ito, H., & Shimizu, E.
Affiliations
  • Niigata Seiryo University (JP)
  • Kitasato University (JP)
  • SHOWA Medical University (JP)
  • Niigata University (JP)
  • Niigata Prefectural Government (JP)
  • National Institute of Occupational Safety and Health (JP)
  • Chiba University (JP)
Corresponding author
Muramatsu, Kumiko
Venue
General Hospital Psychiatry
Publisher
Elsevier BV
Published
2018-05
Volume
52
Pages
64-69
ISSN
0163-8343 (ISSN-L)
OpenAlex
W2794702942
Cited by
345
References
35
Citations by year
2026: 48 · 2025: 88 · 2024: 63 · 2023: 42 · 2022: 47 · 2021: 35 · 2020: 16 · 2019: 4 · 2018: 1 · 2015: 1
FWCI
18.24
Type
journal article
Language
en
Open access
closed
Locations
  • General Hospital Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Pfizer
  • Niigata Seiryo University
Topics
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
  • Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
Keywords
PHQ-9, major depressive disorder, depression screening, primary care, Japanese version, diagnostic accuracy, likelihood ratios, depression severity, SF-8, health-related quality of life
MeSH terms
Patient Health Questionnaire, Adult, Depression, Major Depressive Disorder, Female, Humans, Japan, Male, Middle Aged, Primary Health Care, Psychiatric Status Rating Scales, Sensitivity and Specificity

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