Cited by 1,269Transplantation: Methods and OutcomesOrgan Donation and TransplantationOrgan Transplantation Techniques and Outcomes

The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-sixth adult lung and heart–lung transplantation Report—2019; Focus theme: donor and recipient size match

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Chambers, Daniel C., Cherikh, Wida S., Harhay, Michael O., Hayes, Don, Hsich, Eileen, Khush, Kiran K., Meiser, Bruno, Potena, Luciano +6 more·2019·The Journal of Heart and Lung Transplantation

Abstract

This thirty-sixth adult lung and heart–lung transplant report summarizes data from 69,200 adult lung and 4,128 adult heart-lung transplants performed through June 30, 2018 and reported to the International Thoracic Organ Transplant Registry. With each year's report, we now provide more detailed analyses on a particular focus theme important to patient outcomes. Since 2013, these have been donor and recipient age; retransplantation; early graft failure; indication for transplant; allograft ischemic time; and multiorgan transplantation. Although widely accepted as critical to decision making at the time of receipt of an organ donor offer, there is surprisingly little literature outlining current practice and the impact of size (mis-)matching on outcomes. Hence this year's report focuses on an overall theme of donor and recipient size matching. In addition to reporting donor and recipient height and weight difference for all adult lung and heart-lung transplant recipients stratified by transplant type (bilateral or single) and indication, we report historical trends and associations between size match and survival. The Registry's online slide sets include results from additional analyses and complementary information not included in this publication (see https://ishltregistries.org/registries/slides.asp ).

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Crossref · 10.1016/j.healun.2019.08.001

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49 of 49 references verified0 citation errors · 0 not checkable

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  • The paper says LAM transplant can have better post-transplant survival than other advanced lung diseases and that bilateral transplant may be favored when organs are available.

    “Lung transplant for LAM is relatively rare; however, it is associated with better post-transplant survival compared to other advanced lung diseases.(1, 303–307)”

    From Consensus document for the selection of lung transplant candidates: An update from the International Society for Heart and Lung Transplantation. (2021) · cites this paper as [1]

    The Lung transplantation section (page unavailable) reports that lymphangioleiomyomatosis as an indication for transplantation is favorably associated with survival in a multivariable model. It does not establish that LAM transplantation is relatively rare or recommend bilateral transplantation when organs are available; its favorable association for bilateral transplantation is reported separately, not specifically for LAM. (LLM, conf=0.87)

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  • Lung transplant for lymphangioleiomyomatosis is relatively rare but is associated with better post-transplant survival than other advanced lung diseases.

    “Lung transplant for LAM is relatively rare; however, it is associated with better post-transplant survival compared to other advanced lung diseases.(1, 303–307)”

    From Consensus document for the selection of lung transplant candidates: An update from the International Society for Heart and Lung Transplantation. (2021) · cites this paper as [1]

    The Lung transplantation survival section (page not provided) says that lymphangioleiomyomatosis as an indication for transplantation is favorably associated with survival in a multivariable model. The Indications section gives frequencies for other diagnoses but does not establish how often transplantation is performed for lymphangioleiomyomatosis, so the claim that it is relatively rare is not supported by this copy. (LLM, conf=0.85)

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  • The paper says thoracic malignancy is an uncommon transplant indication and that outcomes data are lacking because many centers abandoned the practice.

    “Thoracic malignancy is a rare indication for lung transplant, accounting for only 0.1% of all lung transplants performed between 1995– 2018.(1) Notably, there is an absence of current data describing outcomes of patients transplanted for thoracic malignancy, likely reflecting the abandonment of this practice in many lung transplant centers.”

    From Consensus document for the selection of lung transplant candidates: An update from the International Society for Heart and Lung Transplantation. (2021) · cites this paper as [1]

    The Lung transplantation—Indications section (page unavailable) points to a table of transplant indications but does not state a thoracic-malignancy count or the claimed 0.1% for 1995–2018. Searches for thoracic malignancy and that percentage also found no passage about a lack of outcomes data or centers abandoning the practice. The citation is attached to the first sentence; the latter explanation appears to be the citing authors’ own statement. (LLM, conf=0.70)

    Experimental — accuracy not yet measured
  • The paper says bronchiolitis obliterans syndrome is not mentioned here; ignore.

    “Non-CF bronchiectasis represents 2.7% of all lung transplants reported to the ISHLT Registry between 1995–2018.”

    From Consensus document for the selection of lung transplant candidates: An update from the International Society for Heart and Lung Transplantation. (2021) · cites this paper as [1]

    The Lung transplantation—Indications section says Table 1 covers transplant indications since January 1995, but the passages available from our copy do not give a figure for non-CF bronchiectasis. Searches for “non-CF bronchiectasis,” “bronchiectasis,” and “2.7%” did not find the claimed proportion; the quoted passages instead discuss other indications and bronchiolitis obliterans syndrome. (LLM, conf=0.70)

    Experimental — accuracy not yet measured
  • Non-cystic fibrosis bronchiectasis accounted for 2.7% of all lung transplants reported to the ISHLT Registry between 1995 and 2018.

    “Non-CF bronchiectasis represents 2.7% of all lung transplants reported to the ISHLT Registry between 1995–2018.(1)”

    From Consensus document for the selection of lung transplant candidates: An update from the International Society for Heart and Lung Transplantation. (2021) · cites this paper as [1]

    The Lung transplantation—Indications section says Table 1 covers transplant indications since January 1995, but the passages available from our copy do not give a figure for non-CF bronchiectasis. Searches for bronchiectasis and 2.7% found no passage establishing the claimed proportion for 1995–2018. (LLM, conf=0.72)

    Experimental — accuracy not yet measured

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Authors
Chambers, D. C., Cherikh, W. S., Harhay, M. O., Hayes, D., Hsich, E., Khush, K. K., Meiser, B., Potena, L., Rossano, J. W., Toll, A. E., Singh, T. P., Sadavarte, A., Zuckermann, A., & Stehlik, J.
Affiliations
International Society for Heart and Lung Transplantation (US)
Corresponding author
Stehlik, Josef
Venue
The Journal of Heart and Lung Transplantation
Publisher
Elsevier BV
Published
2019-10
Volume
38
Issue
10
Pages
1042-1055
ISSN
1053-2498 (ISSN-L)
OpenAlex
W2967129829
Cited by
1,269
References
49
Citations by year
2026: 63 · 2025: 140 · 2024: 189 · 2023: 235 · 2022: 239 · 2021: 256 · 2020: 138 · 2019: 4 · 2018: 3 · 2014: 1
FWCI
152.22
Type
journal article
Language
en
Open access
Locations
  • The Journal of Heart and Lung Transplantation (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Heart, Lung, and Blood Institute (R01HL141892)
Topics
  • Health Sciences › Medicine › Surgery › Transplantation: Methods and Outcomes
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Organ Donation and Transplantation
  • Health Sciences › Medicine › Surgery › Organ Transplantation Techniques and Outcomes
Keywords
lung transplantation, heart-lung transplantation, donor-recipient size matching, post-transplant survival, transplant outcomes, adult transplant recipients
MeSH terms
Adult, Aged, Annual Reports as Topic, Female, Heart, Humans, International Cooperation, Lung, Male, Middle Aged, Organ Size, Postoperative Complications, Registries, Societies, Medical, Lung Transplantation, Heart-Lung Transplantation, Treatment Outcome, Patient Selection, Donor Selection

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