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Cited by 130

The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.

Molecular Basis and Genetic Modifiers of Thalassemia

Mettananda, Sachith, Higgs, Douglas R.·2018·Hematology/Oncology Clinics of North America
DOI 10.1016/j.hoc.2017.11.003
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Crossref · 10.1016/j.hoc.2017.11.003

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  • HBA2 is located closer to the primary regulatory element HS-40 and has promoter variants that enhance transcription, and HBA2 mRNA is generally more stable, contributing to its higher expression levels.

    “This is partly because HBA2 is located closer to the primary regulatory element HS-40 and has promoter variants that enhance transcription. Additionally, HBA2 mRNA is generally more stable, contributing to its higher expression levels [15–17].”

    From Importance of the 3′UTR region in globin synthesis: identification of two novel HBA1 mutations causing α-Thalassemia (2025) · cites this paper as [15]

  • The relatively low number of 3′UTR variants reported in HBA1 (only two) compared to HBA2 (eleven) may be due to higher transcriptional activity of HBA2, which is expressed 2-3 times more than HBA1.

    “The relatively low number of 3′UTR variants reported in HBA1 (only two) compared to HBA2 (eleven) may be due to higher transcriptional activity of HBA2, which is expressed 2–3 times more than HBA1.”

    From Importance of the 3′UTR region in globin synthesis: identification of two novel HBA1 mutations causing α-Thalassemia (2025) · cites this paper as [15]

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Research works printed but not linked: 54

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Metadata

Authors
Mettananda, S., & Higgs, D. R.
Venue
Hematology/Oncology Clinics of North America
Publisher
Elsevier BV
Published
2018-04
Volume
32
Issue
2
Pages
177-191
ISSN
0889-8588
DOI
10.1016/j.hoc.2017.11.003
Cited by
130
References
9
Language
en
Licence

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