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Obstructive sleep apnea is associated with nonsustained ventricular tachycardia in patients with hypertrophic obstructive cardiomyopathy

Wang, Shengwei, Cui, Hao, Song, Changpeng, Zhu, Changsheng, Wu, Rong, Meng, Liukun, Yu, Qinjun, Huang, Xiaohong, Wang, Shuiyun·2019·Heart Rhythm
DOI 10.1016/j.hrthm.2018.12.017
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Abstract

Background Hypertrophic cardiomyopathy (HCM) is associated with arrhythmias and cardiovascular death. Obstructive sleep apnea (OSA) is highly prevalent and independently associated with atrial fibrillation in patients with HCM. Objective The purpose of this study was to determine the relationship between nonsustained ventricular tachycardia (NSVT) and OSA in hypertrophic obstructive cardiomyopathy (HOCM). Methods One hundred thirty consecutive patients with a confirmed diagnosis of HOCM in Fuwai Hospital between September 2017 and May 2018 were included. Polysomnography and Holter electrocardiography were performed in all patients. Results Of 130 patients, 72 (55%) were diagnosed with OSA, including 38 with mild, 21 with moderate, and 13 with severe OSA, and 27 patients (21%) had NSVT. The prevalence of NSVT increased with the severity of OSA (none, mild, moderate, and severe: 12%, 16%, 33%, and 54%, respectively; P Conclusion The presence and severity of OSA in patients with HOCM is independently associated with NSVT, which is a risk factor for sudden cardiac death and cardiovascular death in this population.

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Research works printed but not linked: 28

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Metadata

Authors
Wang, S., Cui, H., Song, C., Zhu, C., Wu, R., Meng, L., Yu, Q., Huang, X., & Wang, S.
ORCID
Wang, Shuiyun
Venue
Heart Rhythm
Publisher
Elsevier BV
Published
2019-05
Volume
16
Issue
5
Pages
694-701
ISSN
1547-5271
DOI
10.1016/j.hrthm.2018.12.017
Cited by
33
References
1
Language
en
Licence
Funders
National Natural Science Foundation of China (81570276)

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