Cited by 43Cardiac Arrhythmias and TreatmentsCardiac electrophysiology and arrhythmiasAtrial Fibrillation Management and Outcomes

Long-term outcome of patients with atrioventricular node reentrant tachycardia

D’Este, Daniele, Zoppo, Franco, Bertaglia, Emanuele, Zerbo, Francesca, Picciolo, Amedeo, Scarabeo, Virginia, Pascotto, Andrea, Pascotto, Pietro·2007·International Journal of Cardiology

Abstract

Background Little information is available on the natural history of patients with AVNRT. The purpose of this study was to compare the outcome of patients with Atrioventricular node reentrant tachycardia (AVNRT) who underwent ablation with those on antiarrhythmic therapy and those not receiving drugs.Methods 93 consecutive patients (mean age=33.5+/-18.1 years) with AVNRT referred to our institution from 1988 to 1993 were prospectively followed-up for a mean of 13.2+/-2.0 years (range=11.4-16.1 years).Results 18 patients underwent ablation (group 1), 24 received antiarrhythmic therapy (group 2), 38 received no drugs or remained on drug therapy for only few months (group 3), 3 died and 10 were lost to follow-up. The frequency of symptoms at the baseline was higher in group 1 than in groups 2 and 3 (7.8+/-3.7, 3.5+/-2.3, 2.3+/-1.9 episodes/month, respectively; p<0.02 in group 1 vs. group 3). At the end of the follow-up 18/18 (100%) of group 1, 14/23 (61%) of group 2 and 17/38 of group 3 (44.7%) reported being asymptomatic for the previous 3 years. Group 3 patients who became asymptomatic had a shorter duration of symptoms before enrolment (3.7+/-1.5 vs. 7.1+/-3.6 years, p<0.05) and a shorter mean length of the tachycardia episodes (3.8+/-2.4 vs. 42.6+/-17.8 min, p<0.02) than patients from the same group who remained symptomatic.Conclusions The main result of this study is that during a long-term follow-up a considerable number of untreated patients with AVNRT become asymptomatic. This finding should be considered for choosing treatment modality and for calculating healthcare costs of ablation vs. medical therapy.

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Crossref · 10.1016/j.ijcard.2006.04.035

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Authors
D’Este, D., Zoppo, F., Bertaglia, E., Zerbo, F., Picciolo, A., Scarabeo, V., Pascotto, A., & Pascotto, P.
Affiliations
Ospedale di Mirano (IT)
Venue
International Journal of Cardiology
Publisher
Elsevier BV
Published
2007-02
Volume
115
Issue
3
Pages
350-353
ISSN
0167-5273 (ISSN-L)
OpenAlex
W1992293632
Cited by
43
References
20
Citations by year
2025: 3 · 2024: 1 · 2023: 1 · 2022: 2 · 2021: 1 · 2020: 3 · 2019: 3 · 2018: 4 · 2017: 3 · 2016: 5 · 2015: 8 · 2014: 3 · 2013: 2
FWCI
0.24
Type
journal article
Language
en
Open access
closed
Locations
  • International Journal of Cardiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
Keywords
atrioventricular nodal reentrant tachycardia, long-term outcomes, catheter ablation, antiarrhythmic therapy, natural history (disease), health care costs
MeSH terms
Adolescent, Adult, Age Factors, Analysis of Variance, Anti-Arrhythmia Agents, Female, Follow-Up Studies, Humans, Male, Middle Aged, Probability, Prospective Studies, Recurrence, Severity of Illness Index, Sex Factors, Tachycardia, Atrioventricular Nodal Reentry, Time Factors, Cohort Studies, Survival Rate, Treatment Outcome, Catheter Ablation, Echocardiography, Transesophageal, Risk Assessment

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