The DOI matches its Crossref record; 56 of the 56 references it cites were found in a registry or an index.
Recent advances in leishmaniasis treatment
Open accessAbstract
About 1.5 million new cases of cutaneous leishmaniasis and 500,000 new cases of visceral leishmaniasis occur each year around the world. For over half a century, the clinical forms of the disease have been treated almost exclusively with pentavalent antimonial compounds. In this review, we describe the arsenal available for treating Leishmania infections, as well as recent advances from research on plants and synthetic compounds as source drugs for treating the disease. We also review some new drug-delivery systems for the development of novel chemotherapeutics. We observe that the pharmaceutical industry should employ its modern technologies, which could lead to better use of plants and their extracts, as well as to the development of synthetic and semi-synthetic compounds. New studies have highlighted some biopharmaceutical technologies in the design of the delivery strategy, such as nanoparticles, liposomes, cochleates, and non-specific lipid transfer proteins. These observations serve as a basis to indicate novel routes for the development and design of effective anti-Leishmania drugs.
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Cites
Biodegradable polymeric nanoparticles based drug delivery systems
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Drug Resistance in Leishmaniasis
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Magnetic nanoparticles for drug delivery
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Metadata
- Authors
- Tiuman, T. S., Santos, A. O., Ueda-Nakamura, T., Filho, B. P. D., & Nakamura, C. V.
- Venue
- International Journal of Infectious Diseases
- Publisher
- Elsevier BV
- Published
- 2011-08
- Volume
- 15
- Issue
- 8
- Pages
- e525-e532
- ISSN
- 1201-9712 (ISSN-L)
- OpenAlex
- W2047581463
- Cited by
- 345
- References
- 56
- FWCI
- 19.70
- Type
- journal article
- Language
- en
- Open access
- gold
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- Tiuman, T. S., Santos, A. O., Ueda-Nakamura, T., Filho, B. P. D., & Nakamura, C. V. (2011). Recent advances in leishmaniasis treatment. International Journal of Infectious Diseases. https://doi.org/10.1016/j.ijid.2011.03.021
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
