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Cited by 353

The DOI matches its Crossref record; 50 of the 50 references it cites were found in a registry or an index.

COVID-19 and healthcare workers: A systematic review and meta-analysis

Open access
Gholami, Mandana, Fawad, Iman, Shadan, Sidra, Rowaiee, Rashed, Ghanem, HedaietAllah, Hassan Khamis, Amar, Ho, Samuel B.·2021·International Journal of Infectious Diseases

Abstract

BACKGROUND: The COVID-19 pandemic has focused attention on the challenges and risks faced by frontline healthcare workers (HCW). This study aimed to describe the clinical outcomes and risk factors for SARS-CoV-2 infection in HCW. METHODS: Three databases were surveyed and 328 articles were identified. Of these, 225 articles did not meet inclusion criteria; therefore, 97 full-text article were reviewed. Finally, after further revision, 30 articles were included in the systematic review and 28 were used for meta-analysis. RESULTS: Twenty-eight studies were identified involving 119,883 patients. The mean age of the patients was 38.37 years (95% CI 36.72-40.03) and males comprised 21.4% (95% CI 12.4-34.2) of the population of HCW. The percentage of HCW who tested positive for COVID-19 was 51.7% (95% CI 34.7-68.2). The total prevalence of comorbidities in seven studies was 18.4% (95% CI 15.5-21.7). The most prevalent symptoms were fever 27.5% (95% CI 17.6-40.3) and cough 26.1% (95% CI 18.1-36). The prevalence of hospitalisation was 15.1% (95% CI 5.6-35) in 13 studies and of death was 1.5% (95% CI 0.5-3.9) in 12 studies. Comparisons of HCW with and without infection showed an increased relative risk for COVID-19 related to personal protective equipment, workplace setting, profession, exposure, contacts, and testing. CONCLUSION: A significant number of HCW were reported to be infected with COVID-19 during the first 6 months of the COVID-19 pandemic, with a prevalence of hospitalisation of 15.1% and mortality of 1.5%. Further data are needed to track the continued risks in HCW as the pandemic evolves and health systems adapt.

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Metadata

Authors
Gholami, M., Fawad, I., Shadan, S., Rowaiee, R., Ghanem, H., Hassan Khamis, A., & Ho, S. B.
Venue
International Journal of Infectious Diseases
Publisher
Elsevier BV
Published
2021-03
Volume
104
Pages
335-346
ISSN
1201-9712 (ISSN-L)
OpenAlex
W3120253194
Cited by
353
References
50
FWCI
10.55
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: COVID-19 and healthcare workers: A systematic review and meta-analysis. https://app.cochat.ai/papers/10.1016/j.ijid.2021.01.013
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Gholami, M., Fawad, I., Shadan, S., Rowaiee, R., Ghanem, H., Hassan Khamis, A., & Ho, S. B. (2021). COVID-19 and healthcare workers: A systematic review and meta-analysis. International Journal of Infectious Diseases. https://doi.org/10.1016/j.ijid.2021.01.013

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