Cited by 80Artificial Intelligence in Healthcare and EducationArtificial Intelligence in EducationArtificial Intelligence in Healthcare

A rapid review on current and potential uses of large language models in nursing

Open access
Hobensack, Mollie, von Gerich, Hanna, Vyas, Pankaj, Withall, Jennifer, Peltonen, Laura-Maria, Block, Lorraine J., Davies, Shauna, Chan, Ryan +6 more·2024·International Journal of Nursing Studies

Abstract

Background The application of large language models across commercial and consumer contexts has grown exponentially in recent years. However, a gap exists in the literature on how large language models can support nursing practice, education, and research. This study aimed to synthesize the existing literature on current and potential uses of large language models across the nursing profession.Methods A rapid review of the literature, guided by Cochrane rapid review methodology and PRISMA reporting standards, was conducted. An expert health librarian assisted in developing broad inclusion criteria to account for the emerging nature of literature related to large language models. Three electronic databases (i.e., PubMed, CINAHL, and Embase) were searched to identify relevant literature in August 2023. Articles that discussed the development, use, and application of large language models within nursing were included for analysis.Results The literature search identified a total of 2028 articles that met the inclusion criteria. After systematically reviewing abstracts, titles, and full texts, 30 articles were included in the final analysis. Nearly all (93 %; n = 28) of the included articles used ChatGPT as an example, and subsequently discussed the use and value of large language models in nursing education (47 %; n = 14), clinical practice (40 %; n = 12), and research (10 %; n = 3). While the most common assessment of large language models was conducted by human evaluation (26.7 %; n = 8), this analysis also identified common limitations of large language models in nursing, including lack of systematic evaluation, as well as other ethical and legal considerations.Discussion This is the first review to summarize contemporary literature on current and potential uses of large language models in nursing practice, education, and research. Although there are significant opportunities to apply large language models, the use and adoption of these models within nursing have elicited a series of challenges, such as ethical issues related to bias, misuse, and plagiarism.Conclusion Given the relative novelty of large language models, ongoing efforts to develop and implement meaningful assessments, evaluations, standards, and guidelines for applying large language models in nursing are recommended to ensure appropriate, accurate, and safe use. Future research along with clinical and educational partnerships is needed to enhance understanding and application of large language models in nursing and healthcare.

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Crossref · 10.1016/j.ijnurstu.2024.104753

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  • Hobensack et al. (2024) focused on bibliometric trends rather than synthesising implementation strategies.

    “Hobensack et al. (2024) focused on bibliometric trends rather than synthesising implementation strategies.”

    From Patterns, advances, and gaps in using ChatGPT and similar technologies in nursing education: A PAGER scoping review (2025) · cites this paper as Hobensack et al., 2024

    The Introduction and Study criteria and synthesis sections describe a rapid review that synthesizes literature on current and potential uses of large language models in nursing, not a study focused on bibliometric trends. The Study characteristics section reports publication patterns, but those are only one part of the review. The paper does not present itself as a synthesis specifically of implementation strategies either. (LLM, conf=0.88)

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  • Most existing reviews of GenAI in nursing education lack structured analytical frameworks for systematically mapping evidence into actionable insights.

    “A few reviews have begun to examine GenAI in nursing education, but most lack structured analytical frameworks for systematically mapping evidence into actionable insights.”

    From Patterns, advances, and gaps in using ChatGPT and similar technologies in nursing education: A PAGER scoping review (2025) · cites this paper as Hobensack et al., 2024

    The Introduction (page unavailable) says few earlier reviews synthesized the literature and that they focused mainly on healthcare broadly; it also says no prior study had summarized overarching themes across nursing practice, education, and research. This supports a gap in nursing-focused synthesis, but the paper does not assess whether most reviews of GenAI in nursing education lack structured analytical frameworks or actionable insights. (LLM, conf=0.82)

    Experimental — accuracy not yet measured
  • The 18 included studies collectively explored diverse applications of AI in nursing across research, practice, and education.

    “The 18 included studies in this umbrella review collectively explored the diverse applications of AI in nursing across research, practice, and education [32-49].”
  • This finding aligns with a previous review of ChatGPT in pharmacy practice, which highlighted a lack of standardized evaluation methods, and with broader healthcare reviews calling for standardized LLM evaluation approaches.

    “This finding aligns with a previous review of ChatGPT in pharmacy practice, which highlighted a lack of standardized evaluation methods, 20 and with broader healthcare reviews calling for standardized LLM evaluation approaches.14,15”
  • A coherent synthesis of emerging evidence on GenAI in nursing education is lacking.

    “However, a coherent synthesis of this emerging evidence is lacking.”

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References 52 · Cited by 80

Research works printed but not linked: 3

  1. Cochrane Rapid Review (RR) Definition.
  2. Li T, Higgins JP, Deeks JJ. Chapter 5: Collecting data . In: Cochrane Handbook for Systematic Reviews of Interventions. Vol 6. 4th ed. ; 2023. Accessed December 28, 2023. https://training.cochrane.org/handbook/current/chapter-05
  3. McAdoo T. How to cite ChatGPT. APA Style. doi:10.1037/0000165-000 · DOI

Authors
Hobensack, M., von Gerich, H., Vyas, P., Withall, J., Peltonen, L.-M., Block, L. J., Davies, S., Chan, R., Van Bulck, L., Cho, H., Paquin, R., Mitchell, J., Topaz, M., & Song, J.
Affiliations
  • Icahn School of Medicine at Mount Sinai (US)
  • University of Arizona (US)
  • Columbia University (US)
  • University of Turku (FI)
  • University of British Columbia (CA)
  • University of Regina (CA)
  • Western University (CA)
  • University of Florida (US)
  • King's College London (GB)
  • University of Colorado Anschutz (US)
  • VNS Health (US)
  • University of Pennsylvania (US)
Corresponding author
Hobensack, Mollie
Venue
International Journal of Nursing Studies
Publisher
Elsevier BV
Published
2024-06
Volume
154
Pages
104753
ISSN
0020-7489 (ISSN-L)
OpenAlex
W4392755271
Cited by
80
References
52
Citations by year
2026: 29 · 2025: 35 · 2024: 16
FWCI
1.82
Type
journal article
Language
en
Open access
Locations
  • International Journal of Nursing Studies (publishedVersion)
  • PubMed (publishedVersion)
  • UTUPub (University of Turku) (submittedVersion)
  • Lirias (KU Leuven) (submittedVersion)
Topics
  • Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
  • Physical Sciences › Computer Science › Information Systems › Artificial Intelligence in Education
  • Health Sciences › Health Professions › Health Information Management › Artificial Intelligence in Healthcare
Keywords
large language models, ChatGPT, nursing education, clinical practice, nursing research, ethical considerations, bias, plagiarism, AI adoption in healthcare
MeSH terms
Education, Nursing, Humans, Language

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