Women’s reported experience of conversion to general anesthesia for cesarean delivery with inadequate neuraxial anesthesia: a qualitative prospective multicenter Danish study
Open accessAbstract
BACKGROUND: The recommended anesthesia for cesarean delivery (CD) is neuraxial anesthesia. Pressure and movement are normal sensations during CD, but women should not experience intraoperative pain. However, some women do. The aim of this study was to investigate how women experience inadequate neuraxial anesthesia during CD that requires conversion to general anesthesia. METHODS: Prospective, multicenter qualitative study. Women, who had experienced inadequate neuraxial anesthesia for CD and conversion to general anesthesia were interviewed three months after the CD and screened for posttraumatic stress. Interviews were transcribed and analyzed using manifest content analysis. RESULTS: During seven months, 23 women were included, and 21 interviewed. Three themes were identified, "The experience of inadequate neuraxial anesthesia in CD", "Not what I had expected" and "Living with the consequences". The women found the testing of the neuraxial block complicated, described the intraoperative pain explicitly, felt unprepared for general anesthesia, and felt that they missed out on their delivery, which often complicated their bonding with the baby. Unanswered questions regarding anesthesia were frequent. In total, four (19%) women screened positive for posttraumatic stress, and 11 (52%) for symptoms of it. CONCLUSION: Intraoperative pain during CD necessitating general anesthesia can severely affect women's delivery experience, their early bonding with the baby and might increase the risk of posttraumatic stress. Anesthesiologists might mitigate this by providing sufficient information, before, during and after the CD, acknowledge and react to intraoperative pain while not transferring responsibility for clinical decision onto the woman, and offer follow-up consultations.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Cites
Tong, A., Sainsbury, P., & Craig, J. (2007) · International Journal for Quality in Health Care · doi:10.1093/intqhc/mzm042 · Cited by 42,509 · see citing works
Graneheim, U. H., & Lundman, B. (2004) · Nurse Education Today · doi:10.1016/j.nedt.2003.10.001 · Cited by 20,772 · see citing works
The Mixed Methods Appraisal Tool (MMAT) version 2018 for information professionals and researchers
Hong, Q. N., Fàbregues, S., Bartlett, G., Boardman, F., Cargo, M., Dagenais, P., Gagnon, M.-P., Griffiths, F., Nicolau, B., O’Cathain, A., et al. (2018) · Education for Information · doi:10.3233/efi-180221 · Cited by 4,737 · see citing works
Trends and projections of caesarean section rates: global and regional estimates
Betran, A. P., Ye, J., Moller, A.-B., Souza, J. P., & Zhang, J. (2021) · BMJ Global Health · doi:10.1136/bmjgh-2021-005671 · Cited by 1,562 · see citing works
Kleinheksel, A. J., Rockich-Winston, N., Tawfik, H., & Wyatt, T. R. (2020) · American Journal of Pharmaceutical Education · doi:10.5688/ajpe7113 · Cited by 1,054 · see citing works
PTSD-8: A Short PTSD Inventory
Hansen, M., Andersen, T. E., Armour, C., Elklit, A., Palić, S., & Mackrill, T. (2010) · Clinical Practice and Epidemiology in Mental Health · doi:10.2174/1745017901006010101 · Cited by 238 · see citing works
Plaat, F., Stanford, S. E. R., Lucas, D. N., Andrade, J., Careless, J., Russell, R. I., Bishop, D. G., Lo, Q., & Bogod, D. G. (2022) · Anaesthesia · doi:10.1111/anae.15717 · Cited by 129 · see citing works
Patel, R., Kua, J., Sharawi, N., Bauer, M. E. B., Blake, L., Moonesinghe, R., & Sultan, P. (2022) · Anaesthesia · doi:10.1111/anae.15657 · Cited by 89 · see citing works
Furuta, M., Sandall, J., & Bick, D. (2013) · Midwifery · doi:10.1016/j.midw.2013.09.001 · Cited by 86 · see citing works
Lopez, U., Meyer, M., Loures, V., Iselin-Chaves, I. A., Epiney, M., Kern, C., & Haller, G. (2017) · Health and Quality of Life Outcomes · doi:10.1186/s12955-017-0692-y · Cited by 83 · see citing works
Failure of communication: a patient’s story
Stanford, S. E. R., & Bogod, D. G. (2016) · International Journal of Obstetric Anesthesia · doi:10.1016/j.ijoa.2016.08.001 · Cited by 57 · see citing works
Intraoperative pain during caesarean delivery: Incidence, risk factors and physician perception
Keltz, A., Heesen, P., Katz, D., Neuman, I., Morgenshtein, A., Azem, K., Binyamin, Y., Hadar, E., Eidelman, L. A., & Orbach‐Zinger, S. (2021) · European Journal of Pain · doi:10.1002/ejp.1856 · Cited by 49 · see citing works
Charles, E., Carter, H., Stanford, S., Blake, L., Eley, V. A., Carvalho, B., Sultan, P., Kua, J., & O’Carroll, J. (2025) · Obstetric Anesthesia Digest · doi:10.1097/01.aoa.0001192372.90104.14 · Cited by 44 · see citing works
Charles, E. A., Carter, H., Stanford, S., Blake, L., Eley, V., Carvalho, B., Sultan, P., Kua, J., & O’Carroll, J. E. (2025) · Anesthesiology · doi:10.1097/aln.0000000000005486 · Cited by 44
Antepartum and intrapartum risk factors and the impact of PTSD on mother and child
Vogel, T. M., & Homitsky, S. C. (2020) · BJA Education · doi:10.1016/j.bjae.2019.11.005 · Cited by 31 · see citing works
Neuraxial anesthesia and pain management for cesarean delivery
Landau, R., & Sultan, P. (2025) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2025.05.018 · Cited by 27 · see citing works
Wilson, R. D., Monks, D. T., Sharawi, N., Bamber, J., Panelli, D. M., Sauro, K. M., Shah, P. S., Muraca, G. M., Metcalfe, A., Wood, S. L., et al. (2026) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2025.01.014 · Cited by 22 · see citing works
Surgical sensation during caesarean section: a qualitative analysis
Jiang, A., Perry, T. B., Walker, K. F., Burfoot, A., & Patterson, L. (2023) · International Journal of Obstetric Anesthesia · doi:10.1016/j.ijoa.2023.103935 · Cited by 14 · see citing works
Intraoperative pain during cesarean delivery: a qualitative concept elicitation study
Callihan, P., Bekemeyer, Z. J. C., Pedreira, R. A., Michel, G., Sukhdeo, H., O’Carroll, J., Carvalho, B., Martinez, E., & Sultan, P. (2025) · International Journal of Obstetric Anesthesia · doi:10.1016/j.ijoa.2025.104748 · Cited by 10 · see citing works
Harkins, S., Thomas, C. D., Hulchafo, I. I., Topaz, M., Landau, R., & Barcelona, V. (2025) · International Journal of Obstetric Anesthesia · doi:10.1016/j.ijoa.2025.104824 · Cited by 2 · see citing works
Inadequate neuraxial anaesthesia during caesarean delivery: a survey of practitioners
Patel, R., Russell, R., Plaat, F., Bogod, D., & Lucas, N. (2023) · International Journal of Obstetric Anesthesia · doi:10.1016/j.ijoa.2023.103905
Sanchez, J., Prabhu, R., Guglielminotti, J., & Landau, R. (2024) · Anaesthesia Critical Care & Pain Medicine · doi:10.1016/j.accpm.2023.101310
O’Carroll, J. E., Conti, D., Gao, N., Carvalho, B., & Sultan, P. (2025) · Anesthesiology · doi:10.1097/aln.0000000000005868
Nedergaard, H. K., Weitling, E. E., Jensen, H. I., & Brøchner, A. C. (2025) · International Journal of Obstetric Anesthesia · doi:10.1016/j.ijoa.2025.104693
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Stanford, S., Vogel, T. M., & Nixon, H. C. (2026) · Anaesthesia · doi:10.1111/anae.70281 · Cited by 3 · see citing works
Singh, S., Alrubaie, N., Smith, M., Kountanis, J. A., Pancaro, C., Yuan, Y., Vlisides, P. E., Clauw, D. J., & DeJonckheere, M. J. (2026) · International Journal of Obstetric Anesthesia · doi:10.1016/j.ijoa.2026.105264 · Cited by 1 · see citing works
When the neuraxial block fails: listening to women’s voices after pain during cesarean delivery
Sassi, K., & Callihan, P. (2026) · International Journal of Obstetric Anesthesia · doi:10.1016/j.ijoa.2026.105191 · Cited by 1 · see citing works
Gendered Pain: How Implicit Bias Shapes Clinical Assessment and Treatment Outcomes for Women
Shim, A. (2026) · American journal of student research. · doi:10.70251/hyjr2348.455360
Measuring What Matters: Advancing Research on Intraoperative Pain During Cesarean Birth
Marchesi, S., Asif, S., Wikkelsø, A. J., & Bjurström, M. F. (2026) · Acta Anaesthesiologica Scandinavica · doi:10.1111/aas.70335
Weiniger, C. F., George, R. B., & Landau, R. (2026) · International Journal of Obstetric Anesthesia · doi:10.1016/j.ijoa.2026.105288
Takenoshita, M., Sharpe, E. E., & O’Carroll, J. (2026) · International Journal of Obstetric Anesthesia · doi:10.1016/j.ijoa.2026.105295
Dempsey, A. G., Selcer, L., Klawetter, S., Starzyk, D., Villareal, R. I., Singhal, S., & Wood, C. (2026) · International Journal of Obstetric Anesthesia · doi:10.1016/j.ijoa.2026.105284
Pain That Falls Through the Gap: Recognition, Uncertainty, and Voice During Caesarean Delivery
Hayhoe, S. A. (2026) · Anesthesia & Analgesia · doi:10.1213/ane.0000000000008363
- Authors
- Nedergaard, H. K., Duch, P., Wikkelso, A. J., Abildgren, M. L., Lund-Olesen, J., Wildgaard, K., & Ekelund, K.
- Affiliations
- University of Southern Denmark (DK)
- Copenhagen University Hospital (DK)
- Aalborg University Hospital (DK)
- Regionshospitalet Viborg (DK)
- University of Copenhagen (DK)
- Corresponding author
- Nedergaard, Helene Korvenius
- Duch, Patricia
- Abildgren, Malene Lund
- Lund-Olesen, Janne
- Wildgaard, Kim
- Ekelund, Kim
- Venue
- International Journal of Obstetric Anesthesia
- Publisher
- Elsevier BV
- Published
- 2026-05
- Volume
- 66
- Pages
- 104882
- ISSN
- 0959-289X (ISSN-L)
- OpenAlex
- W7130819261
- Semantic Scholar
- bda4699527e9d05c8be0412bbf2a5378433d01e4
- Cited by
- 8
- References
- 13
- Citations by year
- 2026: 8
- FWCI
- 50.35
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- International Journal of Obstetric Anesthesia (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Research at the University of Copenhagen (University of Copenhagen) (publishedVersion, cc-by)
- VBN Forskningsportal (Aalborg Universitet) (submittedVersion, cc-by)
- University of Southern Denmark Research Portal (University of Southern Denmark) (submittedVersion, cc-by)
- Funders
- University of Southern Denmark
- Topics
- Health Sciences › Medicine › Surgery › Anesthesia and Pain Management
- Health Sciences › Medicine › Obstetrics and Gynecology › Maternal and Perinatal Health Interventions
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Anesthesia and Sedative Agents
- Keywords
- cesarean section, conversion to general anesthesia, intraoperative pain, patient experience, post-traumatic stress, maternal-fetal bonding, patient information, obstetric anesthesia
- MeSH terms
- Adult, Anesthesia, General, Anesthesia, Obstetrical, Cesarean Section, Denmark, Female, Humans, Pregnancy, Prospective Studies, Qualitative Research
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review