Prevalence of depression in older people with hip fracture: A systematic review and meta-analysis
Abstract
Introduction Hip fracture disrupts general health and is one of the most common physical injuries in the elderly. Depression is the most common mood disorder in older people and one of the main complications of hip fractures.Aim and methods We conducted a meta-analysis to estimate the prevalence of depression in older people with hip fractures. Relevant literature published until July 2019 was obtained and screened according to established inclusion criteria. Two researchers independently carried out quality assessment and data extraction before the meta-analysis. We calculated proportions with 95% confidence intervals (CI). To investigate the sources of heterogeneity, we performed subgroup analyses based on study design, follow-up duration, type of fracture, and gender.Results Twenty-seven studies with a combined sample size of 11958 were included. The overall prevalence of depression in older people with hip fracture was 23% (95% CI: 0.18 to 0.29). The lowest and highest prevalence of depression was in Asia (0.19) and America (0.27) respectively.Conclusion In this systematic review and meta-analysis the estimated prevalence of depression among older hip fracture patients was 23%. Further research is needed to identify strategies for preventing and treating mood disorders in this population.
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MDD is associated with poor bone health.
“A growing body of evidence shows that MDD is associated with poor bone health106-109.”
From Comorbidity between major depressive disorder and physical diseases: a comprehensive review of epidemiology, mechanisms and management (2023) · cites this paper as [109]
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- Authors
- Heidari, M. E., Naghibi Irvani, S. S., Dalvand, P., Khadem, M., Eskandari, F., Torabi, F., & Shahsavari, H.
- Affiliations
- Tehran University of Medical Sciences (IR)
- University of Shahrood (IR)
- Venue
- International Journal of Orthopaedic and Trauma Nursing
- Publisher
- Elsevier BV
- Published
- 2021-02
- Volume
- 40
- Pages
- 100813
- ISSN
- 1878-1241 (ISSN-L)
- OpenAlex
- W3047808026
- Cited by
- 42
- References
- 46
- Citations by year
- 2026: 7 · 2025: 6 · 2024: 11 · 2023: 6 · 2022: 3 · 2021: 8 · 2020: 1
- FWCI
- 1.02
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Orthopaedic and Trauma Nursing (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Hip and Femur Fractures
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Aging, Health, and Disability
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
- Keywords
- depression, hip fracture, older adults, prevalence, mood disorders, fracture complications, gender differences, fracture type
- MeSH terms
- Aged, Depression, Hip Fractures, Humans, Prevalence
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