Cited by 855Aging, Health, and DisabilityMental Health Treatment and AccessHealth and Well-being Studies

Age- and gender-specific prevalence of depression in latest-life - Systematic review and meta-analysis

Luppa, M., Sikorski, C., Luck, T., Ehreke, L., Konnopka, A., Wiese, B., Weyerer, S., König, H.-H. +1 more·2012·Journal of Affective Disorders

Abstract

Objective The objective of the study is to systematically analyze the prevalence of depression in latest life (75+), particularly focusing on age- and gender-specific rates across the latest-life age groups.Design Relevant articles were identified by systematically searching the databases MEDLINE, Web of Science, Cochrane Library and Psycinfo and relevant literature from 1999 onwards was reviewed. Studies based on the community-based elderly population aged 75 years and older were included. Quality of studies was assessed. Meta-analysis was performed using random effects model.Results 24 studies reporting age- and gender-specific prevalence of depression were found. 13 studies had a high to moderate methodical quality. The prevalence of major depression ranged from 4.6% to 9.3%, and that of depressive disorders from 4.5% to 37.4%. Pooled prevalence was 7.2% (95% CI 4.4-10.6%) for major depression and 17.1% (95% CI 9.7-26.1%) for depressive disorders. Potential sources of high heterogeneity of prevalence were study design, sampling strategy, study quality and applied diagnostics of latest life depression.Conclusions Despite the wide variation in estimates, it is evident that latest life depression is common. To reduce variability of study results, particularly sampling strategies (inclusion of nursing home residents and severe cognitively impaired individuals) for the old age study populations should be addressed more thoroughly in future research.

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Crossref · 10.1016/j.jad.2010.11.033

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  • Evidence from other countries suggests that the prevalence of depression tends to increase as age increases.

    “Evidence from other countries (Arias-de la Torre et al., 2018;Luppa et al., 2012;Maske et al., 2016), suggests that the prevalence of depression tends to increase as the age increases.”

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Authors
Luppa, M., Sikorski, C., Luck, T., Ehreke, L., Konnopka, A., Wiese, B., Weyerer, S., König, H.-H., & Riedel-Heller, S. G.
Affiliations
  • Leipzig University (DE)
  • University Medical Center Hamburg-Eppendorf (DE)
  • Medizinische Hochschule Hannover (DE)
  • Central Institute of Mental Health (DE)
Corresponding author
Luppa, M.
Venue
Journal of Affective Disorders
Publisher
Elsevier BV
Published
2012-02
Volume
136
Issue
3
Pages
212-221
ISSN
0165-0327 (ISSN-L)
OpenAlex
W2060854717
Cited by
855
References
53
Citations by year
2026: 44 · 2025: 61 · 2024: 78 · 2023: 70 · 2022: 72 · 2021: 86 · 2020: 70 · 2019: 75 · 2018: 53 · 2017: 55 · 2016: 53 · 2015: 53 · 2014: 38 · 2013: 26 · 2012: 17
FWCI
2.12
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Affective Disorders (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Aging, Health, and Disability
  • Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
  • Social Sciences › Psychology › Clinical Psychology › Health and Well-being Studies
Keywords
depression, oldest old, age-specific prevalence, gender differences, major depressive disorder, depressive disorders, community-dwelling older adults, nursing home residents, cognitive impairment
MeSH terms
Age Factors, Aged, Aged, 80 and over, Depression, Depressive Disorder, Female, Humans, Male, Sex Factors, United States, Prevalence

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