Molecular epidemiology: A multidisciplinary approach to understanding parasitic zoonoses
Abstract
Sound application of molecular epidemiological principles requires working knowledge of both molecular biological and epidemiological methods. Molecular tools have become an increasingly important part of studying the epidemiology of infectious agents. Molecular tools have allowed the aetiological agent within a population to be diagnosed with a greater degree of efficiency and accuracy than conventional diagnostic tools. They have increased the understanding of the pathogenicity, virulence, and host-parasite relationships of the aetiological agent, provided information on the genetic structure and taxonomy of the parasite and allowed the zoonotic potential of previously unidentified agents to be determined. This review describes the concept of epidemiology and proper study design, describes the array of currently available molecular biological tools and provides examples of studies that have integrated both disciplines to successfully unravel zoonotic relationships that would otherwise be impossible utilising conventional diagnostic tools. The current limitations of applying these tools, including cautions that need to be addressed during their application are also discussed.
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Asymptomatic and symptomatic dogs present the same level of zoonotic risk.
“Therefore, these categories present the same level of zoonotic risk, which may not be fully appreciated by pet owners [59,193-195].”
From Pet roundworms and hookworms: A continuing need for global worming (2012) · cites this paper as [195]
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Detection of Fasciola hepatica in Infected Intermediate Hosts Using RT-PCR
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Genotyping of Cryptosporidium parvum With Microsatellite Markers
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A New Approach for the Identification and the Diagnosis ofEimeria mediaParasite of the Rabbit
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Genotyping and detection of multiple infections of Toxoplasma gondii using Pyrosequencing
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Pet roundworms and hookworms: A continuing need for global worming
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- Authors
- Traub, R. J., Monis, P. T., & Robertson, I. D.
- Affiliations
- Murdoch University (AU)
- South Australian Water Corporation (AU)
- Corresponding author
- Traub, R.J.
- Venue
- International Journal for Parasitology
- Publisher
- Elsevier BV
- Published
- 2005-10
- Volume
- 35
- Issue
- 11-12
- Pages
- 1295-1307
- ISSN
- 0020-7519 (ISSN-L)
- OpenAlex
- W2171201230
- Cited by
- 65
- References
- 132
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 2 · 2023: 1 · 2021: 10 · 2019: 4 · 2018: 1 · 2017: 4 · 2016: 3 · 2015: 1 · 2014: 2 · 2013: 4 · 2012: 6
- FWCI
- 0.82
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal for Parasitology (publishedVersion)
- PubMed (publishedVersion)
- Murdoch University Research Portal (submittedVersion)
- Topics
- Health Sciences › Medicine › Pathology and Forensic Medicine › Parasitic infections in humans and animals
- Health Sciences › Veterinary › Small Animals › Helminth infection and control
- Life Sciences › Immunology and Microbiology › Parasitology › Parasitic Infections and Diagnostics
- Keywords
- molecular epidemiology, parasitic zoonoses, zoonotic parasites, research design, host-parasite interactions, parasite taxonomy, zoonotic potential, etiological diagnosis
- MeSH terms
- Animals, Disease Vectors, Host-Parasite Interactions, Humans, Parasites, Parasitic Diseases, Zoonoses, Epidemiologic Studies, Molecular Epidemiology
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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