Cited by 65Parasitic infections in humans and animalsHelminth infection and controlParasitic Infections and Diagnostics

Molecular epidemiology: A multidisciplinary approach to understanding parasitic zoonoses

Traub, R.J., Monis, P.T., Robertson, I.D.·2005·International Journal for Parasitology

Abstract

Sound application of molecular epidemiological principles requires working knowledge of both molecular biological and epidemiological methods. Molecular tools have become an increasingly important part of studying the epidemiology of infectious agents. Molecular tools have allowed the aetiological agent within a population to be diagnosed with a greater degree of efficiency and accuracy than conventional diagnostic tools. They have increased the understanding of the pathogenicity, virulence, and host-parasite relationships of the aetiological agent, provided information on the genetic structure and taxonomy of the parasite and allowed the zoonotic potential of previously unidentified agents to be determined. This review describes the concept of epidemiology and proper study design, describes the array of currently available molecular biological tools and provides examples of studies that have integrated both disciplines to successfully unravel zoonotic relationships that would otherwise be impossible utilising conventional diagnostic tools. The current limitations of applying these tools, including cautions that need to be addressed during their application are also discussed.

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Crossref · 10.1016/j.ijpara.2005.06.008

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Authors
Traub, R. J., Monis, P. T., & Robertson, I. D.
Affiliations
  • Murdoch University (AU)
  • South Australian Water Corporation (AU)
Corresponding author
Traub, R.J.
Venue
International Journal for Parasitology
Publisher
Elsevier BV
Published
2005-10
Volume
35
Issue
11-12
Pages
1295-1307
ISSN
0020-7519 (ISSN-L)
OpenAlex
W2171201230
Cited by
65
References
132
Citations by year
2026: 1 · 2025: 3 · 2024: 2 · 2023: 1 · 2021: 10 · 2019: 4 · 2018: 1 · 2017: 4 · 2016: 3 · 2015: 1 · 2014: 2 · 2013: 4 · 2012: 6
FWCI
0.82
Type
journal article
Language
en
Open access
closed
Locations
  • International Journal for Parasitology (publishedVersion)
  • PubMed (publishedVersion)
  • Murdoch University Research Portal (submittedVersion)
Topics
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Parasitic infections in humans and animals
  • Health Sciences › Veterinary › Small Animals › Helminth infection and control
  • Life Sciences › Immunology and Microbiology › Parasitology › Parasitic Infections and Diagnostics
Keywords
molecular epidemiology, parasitic zoonoses, zoonotic parasites, research design, host-parasite interactions, parasite taxonomy, zoonotic potential, etiological diagnosis
MeSH terms
Animals, Disease Vectors, Host-Parasite Interactions, Humans, Parasites, Parasitic Diseases, Zoonoses, Epidemiologic Studies, Molecular Epidemiology

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