The DOI matches its Crossref record; 82 of the 82 references it cites were found in a registry or an index.
Nano spray drying for encapsulation of pharmaceuticals
Abstract
Graphical abstract Process parameters and formulation variables for a nano spray dryer. Figure. No Caption available. &NA; Many pharmaceuticals such as pills, capsules, or tablets are prepared in a dried and powdered form. In this field, spray drying plays a critical role to convert liquid pharmaceutical formulations into powders. In addition, in many cases it is necessary to encapsulate bioactive drugs into wall materials to protect them against harsh process and environmental conditions, as well as to deliver the drug to the right place and at the correct time within the body. Thus, spray drying is a common process used for encapsulation of pharmaceuticals. In view of the rapid progress of nanoencapsulation techniques in pharmaceutics, nano spray drying is used to improve drug formulation and delivery. The nano spray dryer developed in the recent years provides ultrafine powders at nanoscale and high product yields. In this paper, after explaining the concept of nano spray drying and understanding the key elements of the equipment, the influence of the process parameters on the final powders properties, like particle size, morphology, encapsulation efficiency, drug loading and release, will be discussed. Then, numerous application examples are reviewed for nano spray drying and encapsulation of various drugs in the early stages of product development along with a brief overview of the obtained results and characterization techniques.
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Cites
Applications of spray-drying in microencapsulation of food ingredients: An overview
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Self-citationNanoencapsulation Techniques for Food Bioactive Components: A Review
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Preparation of nanoparticles via spray route
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Chitosan nanoparticles: Preparation, size evolution and stability
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Biopolymer nano-particles and natural nano-carriers for nano-encapsulation of phenolic compounds
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Self-citation
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Alehosseini, E., & Jafari, S. M. (2019) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2019.07.003 · Cited by 242
Self-citationPharmaceutical nanotechnology: from the bench to the market
Mazayen, Z. M., Ghoneim, A. M., Elbatanony, R. S., Basalious, E. B., & Bendas, E. R. (2022) · Future Journal of Pharmaceutical Sciences · doi:10.1186/s43094-022-00400-0 · Cited by 208
Maillard conjugates from spent brewer’s yeast by-product as an innovative encapsulating material
Marson, G. V., Saturno, R. P., Comunian, T. A., Consoli, L., Machado, M. T. D. C., & Hubinger, M. D. (2020) · Food Research International · doi:10.1016/j.foodres.2020.109365 · Cited by 48
Metadata
- Authors
- Arpagaus, C., Collenberg, A., Rütti, D., Assadpour, E., & Jafari, S. M.
- Venue
- International Journal of Pharmaceutics
- Publisher
- Elsevier BV
- Published
- 2018-07
- Volume
- 546
- Issue
- 1-2
- Pages
- 194-214
- ISSN
- 0378-5173 (ISSN-L)
- OpenAlex
- W2804569223
- Cited by
- 389
- References
- 82
- FWCI
- 40.75
- Type
- journal article
- Language
- en
- Open access
- closed
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- Arpagaus, C., Collenberg, A., Rütti, D., Assadpour, E., & Jafari, S. M. (2018). Nano spray drying for encapsulation of pharmaceuticals. International Journal of Pharmaceutics. https://doi.org/10.1016/j.ijpharm.2018.05.037
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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