Cited by 208Nanoparticle-Based Drug DeliveryAdvanced Drug Delivery SystemsPharmacology and Nanomedicine Research

Pharmaceutical nanotechnology: from the bench to the market

Open access
Mazayen, Zaed M., Ghoneim, Amira M., Elbatanony, Rasha S., Basalious, Emad B., Bendas, Ehab R.·2022·Future Journal of Pharmaceutical Sciences

Abstract

Background: Nanotechnology is considered a new and rapidly emerging area in the pharmaceutical and medicinal field. Nanoparticles, as drug delivery systems, impart several advantages concerning improved efficacy as well as reduced adverse drug reactions. Main body: Different types of nanosystems have been fabricated including carbon nanotubes, paramagnetic nanoparticles, dendrimers, nanoemulsions, etc. Physicochemical properties of the starting materials and the selected method of preparation play a significant aspect in determining the shape and characteristics of the developed nanoparticles. Dispersion of preformed polymers, coacervation, polymerization, nano-spray drying and supercritical fluid technology are among the most extensively used techniques for the preparation of nanocarriers. Particle size, surface charge, surface hydrophobicity and drug release are the main factors affecting nanoparticles physical stability and biological performance of the incorporated drug. In clinical practice, many nanodrugs have been used for both diagnostic and therapeutic applications and are being investigated for various indications in clinical trials. Nanoparticles are used for the cure of kidney diseases, tuberculosis, skin conditions, Alzheimer’s disease, different types of cancer as well as preparation of COVID-19 vaccines. Conclusion: In this review, we will confer the advantages, types, methods of preparation, characterization methods and some of the applications of nano-systems.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1186/s43094-022-00400-0

Cites

109 of 109 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Nanotechnology-based approaches enable engineering of nanoscale carriers capable of entrapping, encapsulating, dissolving, or binding APIs within their matrix.

    “Among these, nanotechnology‐based approaches have transformed the field by enabling the engineering of nanoscale carriers capable of entrapping, encapsulating, dissolving, or binding active pharmaceutical ingredients (APIs) within their matrix [26].”

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 2

  1. [4]Mohanraj V Chen Y Nanoparticles-a review Trop J Pharm Res 2006 5 1 561 573
  2. [70]Jahangiri A Barghi L Polymeric nanoparticles: review of synthesismethods and applications in drug delivery J Adv Chem Pharm Mater 2018 1 2 38 47

Cited by

Sorted by citations

Authors
Mazayen, Z. M., Ghoneim, A. M., Elbatanony, R. S., Basalious, E. B., & Bendas, E. R.
Affiliations
  • Future University in Egypt (EG)
  • Cairo University (EG)
Corresponding author
Ghoneim, Amira M.
Venue
Future Journal of Pharmaceutical Sciences
Published
2022-01-15
Volume
8
Issue
1
Pages
12-12
ISSN
  • 2314-7245 (ISSN-L)
  • 2314-7253
OpenAlex
W4205766471
Cited by
208
References
109
Citations by year
2026: 33 · 2025: 58 · 2024: 57 · 2023: 51 · 2022: 9
FWCI
3.01
Type
journal article
Language
en
Open access
Locations
  • Future Journal of Pharmaceutical Sciences (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • Greater South Information System
Topics
  • Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Drug Discovery › Pharmacology and Nanomedicine Research
Keywords
pharmaceutical nanotechnology, nanoparticles, drug delivery systems, nanocarriers, carbon nanotubes, paramagnetic nanoparticles, dendrimers, nanoemulsions, coacervation, nano spray drying, supercritical fluid technology, particle size, surface charge, drug release, physical stability, clinical trials, nanotherapeutics, COVID-19 vaccines, cancer therapy, Alzheimer's disease, tuberculosis, kidney disease

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review