High Dose per Fraction, Hypofractionated Treatment Effects in the Clinic (HyTEC): an overview
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A seminal paper by Emami et al. summarized normal-tissue tolerances to external photon irradiation as they were known in 1991, and these data have been gradually updated and expanded through QUANTEC and HyTEC.
“A seminal paper by Emami et al. ( 6 ) summarized normal-tissue tolerances to external photon irradiation as they were known in 1991, and these data have been gradually updated and expanded through other initiatives such as Quantitative Analysis of Normal Tissue Effects in the Clinic (QUANTEC) and Hypofractionated Treatment Effects in the Clinic (HyTEC) ( 25 , 26 ).”
From Normal-Tissue Tolerance to Radiopharmaceutical Therapies, the Knowns and the Unknowns (2021) · cites this paper as [26]
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Cited by
Sorted by citations
Normal-Tissue Tolerance to Radiopharmaceutical Therapies, the Knowns and the Unknowns
Wahl, R. L., Sgouros, G., Iravani, A., Jacene, H., Pryma, D., Saboury, B., Capala, J., & Graves, S. A. (2021) · Journal of Nuclear Medicine · doi:10.2967/jnumed.121.262751 · Cited by 95 · see citing works
- Authors
- Grimm, J., Marks, L. B., Jackson, A., Kavanagh, B. D., Xue, J., & Yorke, E.
- Affiliations
- Geisinger Medical Center (US)
- University of North Carolina at Chapel Hill (US)
- Memorial Sloan Kettering Cancer Center (US)
- University of Colorado Anschutz (US)
- NYU Langone Health (US)
- Corresponding author
- Grimm, Jimm
- Venue
- International Journal of Radiation Oncology*Biology*Physics
- Publisher
- Elsevier BV
- Published
- 2021-05
- Volume
- 110
- Issue
- 1
- Pages
- 1-10
- ISSN
- 0360-3016 (ISSN-L)
- PMC
- PMC9447432
- OpenAlex
- W3155614206
- Cited by
- 153
- References
- 46
- Citations by year
- 2026: 28 · 2025: 28 · 2024: 42 · 2023: 24 · 2022: 21 · 2021: 10
- FWCI
- 17.69
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- International Journal of Radiation Oncology*Biology*Physics (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Cancer Institute
- National Institutes of Health (P30 CA008748)
- Topics
- Physical Sciences › Physics and Astronomy › Radiation › Advanced Radiotherapy Techniques
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Radiation Therapy and Dosimetry
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Effects of Radiation Exposure
- Keywords
- hypofractionated radiotherapy, high-dose per fraction, stereotactic radiosurgery, stereotactic body radiotherapy, normal tissue complication probability, QUANTEC, HYTEC, normal tissue effects
- MeSH terms
- Radiation Dose Hypofractionation, Systematic Reviews as Topic, Age Factors, Dose-Response Relationship, Radiation, Humans, Neoplasms, Organ Specificity, Radiotherapy Planning, Computer-Assisted, Radiosurgery, Practice Guidelines as Topic, Organs at Risk
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