Acute mesenteric thrombosis in two patients with COVID-19. Two cases report and literature review
Open accessAbstract
Introduction: The coronavirus disease 2019 (COVID-19) affects mainly the respiratory system, other organs may be involved, usually due to coagulation disturbances that lead to a high rate of thrombotic complications. Case presentation: The first patient is 45 years-old who has been exposed to SARS CoV-2. Upon admission due to acute abdomen evidence surgery is performed in which an intestinal resection with an adequate post-surgical evolution takes place so the patient is discharged after 4 days with a prescription for oral anticoagulants. The second one is 42 years-old and has comorbidities. The patient is admitted upon evidence of COVID-19, after showing signs of vein mesenteric ischemia in a CT scan surgery is performed, however the patient dies 24 h after the intervention. Discussion: Within severe cases of patients with COVID-19 the incidence of a symptomatology or gastrointestinal complications is high (39–73.8%). Thromboprophylaxis is recommended to all patients admitted for COVID-19, starting with heparin of low molecular weight as prophylaxis, as well as continuing with oral anticoagulants after being discharged. Conclusion: Despite the fact that knowledge of the disease is rapidly advancing, all available treatments are still nonspecific to SARS-CoV-2 and the optimal management of COVID-19 remains unclear. An unexplained clinical picture should raise the suspicion for rare conditions such as mesenteric thrombosis. Adequate prophylactic measures should be implemented both during hospitalization and after discharge. Highlights:
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30 case reports or case series presented 34 cases of acute bowel ischemia in patients positive for SARS-CoV-2 infection in different clinical settings.
“We also identified 30 case reports or case series [22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51] presenting 34 cases of acute bowel ischemia in patients positive for SARS-CoV-2 infection in different clinical settings.”
From Acute mesenteric ischemia in COVID-19 patients (2021) · cites this paper as [27]
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- Authors
- Rodriguez-Nakamura, R. M., Gonzalez-Calatayud, M., & Martinez Martinez, A. R.
- Affiliations
- Hospital General de México (MX)
- Corresponding author
- Rodriguez-Nakamura, Reiko M.
- Venue
- International Journal of Surgery Case Reports
- Published
- 2020-01
- Volume
- 76
- Issue
- C
- Pages
- 409-414
- ISSN
- 2210-2612 (ISSN-L)
- PMC
- PMC7560267
- OpenAlex
- W3092892540
- Cited by
- 42
- References
- 21
- Citations by year
- 2025: 3 · 2024: 2 · 2023: 6 · 2022: 12 · 2021: 19
- FWCI
- 1.21
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- International Journal of Surgery Case Reports (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Health Sciences › Medicine › Surgery › Abdominal vascular conditions and treatments
- Health Sciences › Medicine › Internal Medicine › Venous Thromboembolism Diagnosis and Management
- Keywords
- COVID-19 pandemic, SARS-CoV-2, mesenteric thrombosis, mesenteric ischemia, acute abdomen, gastrointestinal complications, thromboprophylaxis, low molecular weight heparin, oral anticoagulants, bowel resection, coagulopathy
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