Molecular and cellular basis of rheumatoid joint destruction

Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis

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Infliximab (chimeric anti-tumour necrosis factor α monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial

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Tissue inhibitors of metalloproteinases: evolution, structure and function

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Regulation of matrix metalloproteinases: An overview

Chakraborti, S., Mandal, M., Das, S. K., Mandal, A., & Chakraborti, T. (2003) · Molecular and Cellular Biochemistry · doi:10.1023/a:1026028303196 · Cited by 1,123 · see citing works

mRNA is an endogenous ligand for toll-like receptor 3

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Microscopic polyangiitis: Clinical and laboratory findings in eighty-five patients

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Outcomes of total hip and knee replacement: Preoperative functional status predicts outcomes at six months after surgery

Fortin, P. R., Clarke, A. E., Joseph, L., Liang, M. H., Tänzer, M., Ferland, D., Phillips, C., Partridge, A. J., B�lisle, P., Fossel, A. H., et al. (1999) · Arthritis & Rheumatism · doi:10.1002/1529-0131(199908)42:8 · Cited by 708 · see citing works

Lymphoid Neogenesis in Rheumatoid Synovitis

Takemura, S., Braun, A. B., Crowson, C. S., Kurtin, P. J., Cofield, R. H., O’Fallon, W. M., Goronzy, J. J., & Weyand, C. M. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.167.2.1072 · Cited by 659 · see citing works

Synovial fibroblasts of patients with rheumatoid arthritis attach to and invade normal human cartilage when engrafted into SCID mice.

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Heat-shock proteins induce T-cell regulation of chronic inflammation

van Eden, W., van der Zee, R., & Prakken, B. J. (2005) · Nature reviews. Immunology · doi:10.1038/nri1593 · Cited by 534 · see citing works

IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis synovial fibroblasts via NF-κB- and PI3-kinase/Akt-dependent pathways

Hwang, S., Kim, J., Kim, K., Park, M., Moon, Y., Kim, W., & Kim, H. (2004) · Arthritis Research & Therapy · doi:10.1186/ar1038 · Cited by 405 · see citing works

Analysis of 16 different matrix metalloproteinases (MMP-1 to MMP-20) in the synovial membrane: different profiles in trauma and rheumatoid arthritis

Konttinen, Y. T., Ainola, M., Valleala, H., Ma, J., Ida, H., Mandelin, J., Kinne, R. W., Santavirta, S. S., Sorsa, T. A., López-Otı́n, C., et al. (1999) · Annals of the Rheumatic Diseases · doi:10.1136/ard.58.11.691 · Cited by 405 · see citing works

RNA released from necrotic synovial fluid cells activates rheumatoid arthritis synovial fibroblasts via toll‐like receptor 3

Brentano, F., Schorr, O., Gay, R. E., Gay, S., & Kyburz, D. (2005) · Arthritis & Rheumatism · doi:10.1002/art.21273 · Cited by 377 · see citing works

The induction of matrix metalloproteinase and cytokine expression in synovial fibroblasts stimulated with immune cell microparticles

Distler, J. H. W., Jüngel, A., Huber, L. C., Seemayer, C. A., Reich, C. F., Gay, R. E., Michel, B. A., Fontana, A., Gay, S., Pisetsky, D. S., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409781102 · Cited by 328 · see citing works

Magnetic resonance imaging-determined synovial membrane volume as a marker of disease activity and a predictor of progressive joint destruction in the wrists of patients with rheumatoid arthritis

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Galectin 3 and its binding protein in rheumatoid arthritis

Ohshima, S., Kuchen, S., Seemayer, C. A., Kyburz, D., Hirt, A., Klinzing, S., Michel, B. A., Gay, R. E., Liu, F., Gay, S., et al. (2003) · Arthritis & Rheumatism · doi:10.1002/art.11287 · Cited by 302 · see citing works

Intra-articularly localized bacterial DNA containing CpG motifs induces arthritis

Deng, G., Nilsson, I.-M., Verdrengh, M., Collins, L. V., & Tarkowski, A. (1999) · Nature Medicine · doi:10.1038/9554 · Cited by 295 · see citing works

Nuclear factor–kB in rheumatoid synovium. Localization of P50 and P65

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Lymphoid Chemokine B Cell-Attracting Chemokine-1 (CXCL13) Is Expressed in Germinal Center of Ectopic Lymphoid Follicles Within the Synovium of Chronic Arthritis Patients

Shi, K., Hayashida, K., Kaneko, M., Hashi­moto, J., Tomita, T., Lipsky, P. E., Yoshikawa, H., & Ochi, T. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.1.650 · Cited by 280 · see citing works

CONTRIBUTION OF INTERLEUKIN 17 TO SYNOVIUM MATRIX DESTRUCTION IN RHEUMATOID ARTHRITIS

Chabaud, M., Garnero, P., Dayer, J., Guerne, P., Fossiez, F., & Miossec, P. (2000) · Cytokine · doi:10.1006/cyto.2000.0681 · Cited by 277 · see citing works

Chemokine Secretion of Rheumatoid Arthritis Synovial Fibroblasts Stimulated by Toll-Like Receptor 2 Ligands

Pierer, M., Rethage, J., Seibl, R., Lauener, R. P., Brentano, F., Wagner, U. G., Häntzschel, H., Michel, B. A., Gay, R. E., Gay, S., et al. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.2.1256 · Cited by 273 · see citing works

Synoviolin/Hrd1, an E3 ubiquitin ligase, as a novel pathogenic factor for arthropathyPreprint

Amano, T., Yamasaki, S., Yagishita, N., Tsuchimochi, K., Shin, H., Kawahara, K., Aratani, S., Fujita, H., Zhang, L., Ikeda, R., et al. (2003) · Genes & Development · doi:10.1101/gad.1096603 · Cited by 270 · see citing works

Molecular and cellular mechanisms of joint destruction in rheumatoid arthritis: two cellular mechanisms explain joint destruction?

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Rapid onset synovial inflammation and hyperplasia induced by transforming growth factor beta.

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The synovial expression and serum levels of interleukin-6, interleukin-11, leukemia inhibitory factor, and oncostatin M in rheumatoid arthritis.

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Nuclear factor kappaB/p50 activates an element in the distal matrix metalloproteinase 1 promoter in interleukin-1beta-stimulated synovial fibroblasts.

Vincenti, M., Coon, C. I., & Brinckerhoff, C. (1998) · Arthritis & Rheumatism · doi:10.1002/1529-0131(199811)41:11 · Cited by 239 · see citing works

Microparticles as regulators of inflammation: Novel players of cellular crosstalk in the rheumatic diseases

Distler, J. H. W., Pisetsky, D. S., Huber, L., Kalden, J. R., Gay, S., & Distler, O. (2005) · Arthritis & Rheumatism · doi:10.1002/art.21350 · Cited by 231 · see citing works

Regulation of IL-6 and IL-8 Expression in Rheumatoid Arthritis Synovial Fibroblasts: the Dominant Role for NF-κB But Not C/EBPβ or c-Jun

Georganas, C., Liu, H., Perlman, H., Hoffmann, A., Thimmapaya, B., & Pope, R. M. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.165.12.7199 · Cited by 220 · see citing works

Regional analysis of <i>p53</i> mutations in rheumatoid arthritis synovium

Yamanishi, Y., Boyle, D. L., Rosengren, S., Green, D. R., Zvaifler, N. J., & Firestein, G. S. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.152333199 · Cited by 214 · see citing works

Long-term outcome and prognosis in oligoarticular-onset juvenile idiopathic arthritis

Guillaume, S., Prieur, A., Coste, J., & Job-Deslandre, C. (2000) · Arthritis & Rheumatism · doi:10.1002/1529-0131(200008)43:8 · Cited by 213 · see citing works

Apoptosis in rheumatoid arthritis

Baier, A., Meineckel, I., Gay, S., & Pap, T. (2003) · Current Opinion in Rheumatology · doi:10.1097/00002281-200305000-00015 · Cited by 208 · see citing works

LINE-1 retrotransposons: Modulators of quantity and quality of mammalian gene expression?

Han, J. S., & Boeke, J. D. (2005) · BioEssays · doi:10.1002/bies.20257 · Cited by 206 · see citing works

Intraarticular injection of hyaluronan as treatment for knee osteoarthritis: What is the evidence?

Brandt, K. D., Smith, G. N., & Simon, L. S. (2000) · Arthritis & Rheumatism · doi:10.1002/1529-0131(200006)43:6 · Cited by 204 · see citing works

Local Proliferation of Fibroblast‐Like Synoviocytes Contributes to Synovial Hyperplasia

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Apoptosis in rheumatoid arthritis

Tak, P. P., & Firestein, G. S. (1999) · Birkhäuser Basel eBooks · doi:10.1007/978-3-0348-8741-0_9 · Cited by 198 · see citing works

Bacterial peptidoglycans but not CpG oligodeoxynucleotides activate synovial fibroblasts by toll‐like receptor signaling

Kyburz, D., Rethage, J., Seibl, R., Lauener, R. P., Gay, R. E., Carson, D. A., & Gay, S. (2003) · Arthritis & Rheumatism · doi:10.1002/art.10848 · Cited by 195 · see citing works

Histomorphological Basis of Articular Cartilage Destruction in Rheumatoid Arthritis

Fassbender, H. G. (1983) · Collagen and Related Research · doi:10.1016/s0174-173x(83)80040-5 · Cited by 195 · see citing works

The Human Endoplasmic Reticulum Molecular Chaperone BiP Is an Autoantigen for Rheumatoid Arthritis and Prevents the Induction of Experimental Arthritis

Corrigall, V., Bodman‐Smith, M. D., Fife, M. S., Cañas, B., Myers, L. K., Wooley, P. H., Soh, C., Staines, N. A., Pappin, D., Berlo, S. E., et al. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.3.1492 · Cited by 193 · see citing works

Activation of synovial fibroblasts in rheumatoid arthritis: lack of expression of the tumour suppressor PTEN at sites of invasive growth and destruction

Pap, T., Franz, J. K., Hummel, K. M., Jeisy, E., Gay, R., & Gay, S. (1999) · Arthritis Research & Therapy · doi:10.1186/ar69 · Cited by 183 · see citing works

Involvement of APO2 ligand/TRAIL in activation-induced death of Jurkat and human peripheral blood T cells

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Diverse Transcriptional Response of CD4+ T Cells to Stromal Cell-Derived Factor (SDF)-1: Cell Survival Promotion and Priming Effects of SDF-1 on CD4+ T Cells

Suzuki, Y., Rahman, M., & Mitsuya, H. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.167.6.3064 · Cited by 179 · see citing works

Nuclear Factor κB Activity Is Essential for Matrix Metalloproteinase-1 and -3 Upregulation in Rabbit Dermal Fibroblasts

Bond, M., Baker, A. H., & Newby, A. C. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.1551 · Cited by 173 · see citing works

Human IL-1Ra gene transfer into human synovial fibroblasts is chondroprotective

Müller‐Ladner, U., Roberts, C. R., Franklin, B. N., Gay, R. E., Robbins, P. D., Evans, C. H., & Gay, S. (1997) · The Journal of Immunology · doi:10.4049/jimmunol.158.7.3492 · Cited by 167 · see citing works

Macrophage Migration Inhibitory Factor Up-regulates Matrix Metalloproteinase-9 and -13 in Rat Osteoblasts

Onodera, S., Nishihira, J., Iwabuchi, K., Koyama, Y., Yoshida, K., Tanaka, S., & Minami, A. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m106020200 · Cited by 165 · see citing works

Integration of the NF-κB and mitogen-activated protein kinase/AP-1 pathways at the Collagenase-1 promoter: Divergence of IL-1 and TNF-dependent signal transduction in rabbit primary synovial fibroblasts

Barchowsky, A., Frleta, D., & Vincenti, M. P. (2000) · Cytokine · doi:10.1006/cyto.2000.0743 · Cited by 158 · see citing works

Synovial biology and T cells in rheumatoid arthritis

Tran, C. N., Lundy, S. K., & Fox, D. A. (2005) · Pathophysiology · doi:10.1016/j.pathophys.2005.07.005 · Cited by 144 · see citing works

Effector Function of Resting T Cells: Activation of Synovial Fibroblasts

Yamamura, Y., Gupta, R., Morita, Y., He, X., Pai, R., Endres, J., Freiberg, A., Chung, K. C., & Fox, D. A. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.4.2270 · Cited by 120 · see citing works

Regulation of p53 by macrophage migration inhibitory factor in inflammatory arthritis

Leech, M. T., Lacey, D. C., Xue, J. R., Santos, L. L., Hutchinson, P. E., Wolvetang, E. J., David, J. R., Bucala, R., & Morand, E. F. (2003) · Arthritis & Rheumatism · doi:10.1002/art.11165 · Cited by 114 · see citing works

Direct evidence of high DNA binding activity of transcription factor AP‐1 in rheumatoid arthritis synovium

Asahara, H., Fujisawa, K., Kobata, T., Hasunuma, T., Maeda, T., Asanuma, M., Ogawa, N., Inoue, H., Sumida, T., & Nishioka, K. (1997) · Arthritis & Rheumatism · doi:10.1002/art.1780400520 · Cited by 114 · see citing works

Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of TIMP-1 and TIMP-3

van der Laan, W. H., Quax, P. H. A., Seemayer, C. A., Huisman, L. G. M., Pieterman, E., Grimbergen, J. M., Verheijen, J. H., Breedveld, F. C., Gay, R. E., Gay, S., et al. (2003) · Gene Therapy · doi:10.1038/sj.gt.3301871 · Cited by 113 · see citing works

Control of fibroblast‐like synoviocyte proliferation by macrophage migration inhibitory factor

Lacey, D. C., Sampey, A. V., Mitchell, R. A., Bucala, R., Santos, L., Leech, M. T., & Morand, E. F. (2003) · Arthritis & Rheumatism · doi:10.1002/art.10733 · Cited by 111 · see citing works

Fibroblast-Like Synoviocytes from Rheumatoid Arthritis Patients Express Functional IL-15 Receptor Complex: Endogenous IL-15 in Autocrine Fashion Enhances Cell Proliferation and Expression of Bcl-xL and Bcl-2

Kurowska, W., Rudnicka, W., Kontny, E., Janicka, I., Chorazy, M., Kowalczewski, J. B., Ziółkowska, M., Ferrari‐Lacraz, S., Strom, T. B., & Maśliński, W. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.169.4.1760 · Cited by 110 · see citing works

Inhibition of antigen‐presenting cell function and stimulation of human peripheral blood mononuclear cells to express an antiinflammatory cytokine profile by the stress protein BiP: Relevance to the treatment of inflammatory arthritis

Corrigall, V., Bodman‐Smith, M. D., Brunst, M., Cornell, H. R., & Panayi, G. S. (2004) · Arthritis & Rheumatism · doi:10.1002/art.20134 · Cited by 106 · see citing works

Total-body bone mineral content in non–corticosteroid-treated postpubertal females with juvenile rheumatoid arthritis: Frequency of osteopenia and contributing factors

Henderson, C. J., SPECKER, B. L., Sierra, R. I., Campaigne, B. N., & Lovell, D. J. (2000) · Arthritis & Rheumatism · doi:10.1002/1529-0131(200003)43:3 · Cited by 103 · see citing works

ONCOGENES IN RHEUMATOID ARTHRITIS

Müller‐Ladner, U., Kriegsmann, J., Gay, R. E., & Gay, S. (1995) · Rheumatic Disease Clinics of North America · doi:10.1016/s0889-857x(21)00462-2 · Cited by 103 · see citing works

Arthritogenic Properties of Double-Stranded (Viral) RNA

Zare, F., Bokarewa, M. I., Nenonen, N. P., Bergström, T. B., Alexopoulou, L., Flavell, R. A., & Tarkowski, A. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.9.5656 · Cited by 97 · see citing works

Synovial activation in rheumatoid arthritis

Ospelt, C. (2004) · Frontiers in bioscience · doi:10.2741/1399 · Cited by 97 · see citing works

Prostaglandin E2 is an enhancer of interleukin‐1β–induced expression of membrane‐associated prostaglandin E synthase in rheumatoid synovial fibroblasts

Kojima, F., Naraba, H., Sasaki, Y., Beppu, M., Aoki, H., & Kawai, S. (2003) · Arthritis & Rheumatism · doi:10.1002/art.11261 · Cited by 90 · see citing works

Trichostatin A sensitises rheumatoid arthritis synovial fibroblasts for TRAIL-induced apoptosis

Jüngel, A., Barešová, V., Ospelt, C., Simmen, B. R., Michel, B. A., Gay, R. E., Gay, S., Seemayer, C. A., & Neidhart, M. (2005) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2005.044065 · Cited by 89 · see citing works

FLICE‐inhibitory protein expression in synovial fibroblasts and at sites of cartilage and bone erosion in rheumatoid arthritis

Schedel, J., Gay, R. E., Kuenzler, P., Seemayer, C. A., Simmen, B. R., Michel, B. A., & Gay, S. (2002) · Arthritis & Rheumatism · doi:10.1002/art.10309 · Cited by 88 · see citing works

Galectin-3 is induced in rheumatoid arthritis synovial fibroblasts after adhesion to cartilage oligomeric matrix protein

Neidhart, M., Zaucke, F., von Knoch, R., Jüngel, A., Michel, B. A., Gay, R. E., & Gay, S. (2004) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2004.023135 · Cited by 86 · see citing works

Interleukin-18 Induces Rheumatoid Arthritis Synovial Fibroblast CXC Chemokine Production through NFκB Activation

Morel, J., Park, C. C., Kumar, P., & Koch, A. E. (2001) · Laboratory Investigation · doi:10.1038/labinvest.3780351 · Cited by 84 · see citing works

Signal transduction pathways: new targets for treating rheumatoid arthritis

Morel, J., & Berenbaum, F. (2004) · Joint Bone Spine · doi:10.1016/j.jbspin.2004.03.004 · Cited by 79 · see citing works

Cooperation of Ras‐ and c‐Myc–dependent pathways in regulating the growth and invasiveness of synovial fibroblasts in rheumatoid arthritis

Pap, T., Nawrath, M., Heinrich, J., Bosse, M., Baier, A., Hummel, K. M., Petrow, P. K., Kuchen, S., Michel, B. A., Gay, R. E., et al. (2004) · Arthritis & Rheumatism · doi:10.1002/art.20461 · Cited by 78 · see citing works

Expression of Fas Antigen and Fas Ligand in the Rheumatoid Synovial Tissue

Asahara, H., Hasumuna, T., Kobata, T., Yagita∥, H., Okumura, K., Inoue, H., Gay, S., Sumida, T., & Nishioka, K. (1996) · Clinical Immunology and Immunopathology · doi:10.1006/clin.1996.0153 · Cited by 74 · see citing works

Cartilage Destruction Mediated by Synovial Fibroblasts Does Not Depend on Proliferation in Rheumatoid Arthritis

Seemayer, C. A., Kuchen, S., Kuenzler, P., Řihošková, V., Rethage, J., Aicher, W. K., Michel, B. A., Gay, R. E., Kyburz, D., Neidhart, M., et al. (2003) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)64289-7 · Cited by 74 · see citing works

Tumour necrosis factor activates the mitogen-activated protein kinases p38α and ERK in the synovial membrane in vivo

Görtz, B., Hayer, S., Tuerk, B., Zwerina, J., Smolen, J. S., & Schett, G. A. (2005) · Arthritis Research & Therapy · doi:10.1186/ar1797 · Cited by 72 · see citing works

Comparative expression of the LINE-1 p40 protein in human breast carcinomas and normal breast tissues.

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NF‐κB–regulated expression of cellular FLIP protects rheumatoid arthritis synovial fibroblasts from tumor necrosis factor α–mediated apoptosis

Bai, S., Liu, H., Chen, K., Eksarko, P., Perlman, H., Moore, T. L., & Pope, R. M. (2004) · Arthritis & Rheumatism · doi:10.1002/art.20680 · Cited by 63 · see citing works

Stress cytokines: pivotal proteins in immune regulatory networks

Panayi, G. S., Corrigall, V., & Henderson, B. E. (2004) · Current Opinion in Immunology · doi:10.1016/j.coi.2004.05.017 · Cited by 62 · see citing works

NF-κB as a target for anti-inflammatory gene therapy: suppression of inflammatory responses in monocytic and stromal cells by stable gene transfer of IκBα cDNA

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The L1 Retroelement-related p40 Protein Induces p38δ MAP Kinase

Kuchen, S., Seemayer, C. A., Rethage, J., von Knoch, R., Kuenzler, P., Michel, B. A., Gay, R. E., Gay, S., & Neidhart, M. (2003) · Autoimmunity · doi:10.1080/08916930310001637977 · Cited by 57 · see citing works

Synoviocytes synthesize, bind, and respond to basic fibroblast growth factor

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Importance of NF-κB in rheumatoid synovial tissues: in situ NF-κB expression and in vitro study using cultured synovial cells

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Alternatively spliced CS-1 fibronectin isoform and its receptor VLA-4 in rheumatoid arthritis synovium.

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Stimulation of human synovial fibroblast DNA synthesis by platelet-derived growth factor and fibroblast growth factor. Differences to the activation by IL-1.

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p53 in rheumatoid arthritis synovial fibroblasts at sites of invasion

Seemayer, C. A., Kuchen, S., Neidhart, M., Kuenzler, P., Řihošková, V., Neumann, E., Pruschy, M. N., Aicher, W. K., Müller-Ladner, U., Gay, R. E., et al. (2003) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2003.007401 · Cited by 45 · see citing works

Nuclear antigen histone H1 is primarily involved in lupus erythematosus cell formation

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Galectin-3 and L1 retrotransposons in human breast carcinomas

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Rheumatoid synovial fibroblasts are stimulated by the cellular adhesion to T cells through lymphocyte function associated antigen-1/intercellular adhesion molecule-1.

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Succinate induces synovial angiogenesis in rheumatoid arthritis through metabolic remodeling and HIF-1α/VEGF axis

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Identification of intra-group, inter-individual, and gene-specific variances in mRNA expression profiles in the rheumatoid arthritis synovial membrane

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MicroRNAs in Rheumatoid Arthritis

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MLN3897 plus methotrexate in patients with rheumatoid arthritis: Safety, efficacy, pharmacokinetics, and pharmacodynamics of an oral CCR1 antagonist in a phase IIa, double‐blind, placebo‐controlled, randomized, proof‐of‐concept study

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Phospholipases of Mineralization Competent Cells and Matrix Vesicles: Roles in Physiological and Pathological Mineralizations

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Stimulatory Role of Lysophosphatidic Acid in Cyclooxygenase-2 Induction by Synovial Fluid of Patients with Rheumatoid Arthritis in Fibroblast-Like Synovial Cells

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Successful tumour necrosis factor (TNF) blocking therapy suppresses oxidative stress and hypoxia-induced mitochondrial mutagenesis in inflammatory arthritis

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Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration

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Defective T-Cell Apoptosis and T-Regulatory Cell Dysfunction in Rheumatoid Arthritis

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Epigenome Analysis Reveals TBX5 as a Novel Transcription Factor Involved in the Activation of Rheumatoid Arthritis Synovial Fibroblasts

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Phosphatidylserine-containing liposomes suppress inflammatory bone loss by ameliorating the cytokine imbalance provoked by infiltrated macrophages

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Serum Matrix Metalloproteinase-3 in Comparison with Acute Phase Proteins as a Marker of Disease Activity and Radiographic Damage in Early Rheumatoid Arthritis

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Redox‐Mediated Angiogenesis in the Hypoxic Joint of Inflammatory Arthritis

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Sulforaphane has opposing effects on TNF-alpha stimulated and unstimulated synoviocytes

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Effects of berberine on human rheumatoid arthritis fibroblast-like synoviocytes

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Contribution of Serum Inflammatory Markers to Changes in Bone Mineral Content and Density in Postmenopausal Women: A 1-Year Investigation

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Bone morphogenetic proteins in destructive and remodeling arthritis

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Cartilage Repair In Vivo: The Role of Migratory Progenitor Cells

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The Mal/TIRAP S180L and TLR4 G299D polymorphisms are not associated with susceptibility to, or severity of, rheumatoid arthritis

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Dietary Vitamin E and Quercetin Modulate Inflammatory Responses of Collagen-Induced Arthritis in Mice

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The CO-releasing molecule CORM-3 protects against articular degradation in the K/BxN serum transfer arthritis model

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Therapeutic Effect of Emodin on Collagen-Induced Arthritis in Mice

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Galectins in the Pathogenesis of Rheumatoid Arthritis

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Differential effect of IL-1β and TNF-α on the production of IL-6, IL-8 and PGE2 in fibroblast-like synoviocytes and THP-1 macrophages

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Ozone induces autophagy in rat chondrocytes stimulated with IL-1β through the AMPK/mTOR signaling pathway

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Expression of Osteoarthritis Marker YKL-39 is Stimulated by Transforming Growth Factor Beta (TGF-beta) and IL-4 in Differentiating Macrophages

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7,3′-dimethoxy hesperetin inhibits inflammation by inducing synovial apoptosis in rats with adjuvant-induced arthritis

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Nrf2 activation improves experimental rheumatoid arthritis

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Expression of Osteoarthritis Marker YKL-39 is Stimulated by Transforming Growth Factor Beta (TGF-beta) and IL-4 in Differentiating Macrophages.

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Neo-Epitopes—Fragments of Cartilage and Connective Tissue Degradation in Early Rheumatoid Arthritis and Unclassified Arthritis

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Gender-Specific Effects of Genetic Variants within Th1 and Th17 Cell-Mediated Immune Response Genes on the Risk of Developing Rheumatoid Arthritis

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Lack of association of TLR4 polymorphisms with susceptibility to rheumatoid arthritis and ankylosing spondylitis: A meta-analysis

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