Endogenous Naive CD8+ T Cell Precursor Frequency Regulates Primary and Memory Responses to Infection
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- Stochastic Expansions Maintain the Clonal Stability of CD8+ T Cell Populations Undergoing Memory Inflation Driven by Murine CytomegalovirusCorinne J. Smith, Vanessa Venturi, Máire F. Quigley, Holly Turula, Emma Gostick D, Kristin Ladell, Brenna J. Hill, Danielle Himelfarb, Kylie M. Quinn, Hui Yee Greenaway et al. · 2019 · The Journal of Immunology
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- Lack of Original Antigenic Sin in Recall CD8+ T Cell ResponsesDietmar Zehn, Michael J. Turner, Leo Lefrançois, Michael J. Bevan · 2010 · The Journal of Immunology
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- Mycobacterium tuberculosis Directs Immunofocusing of CD8+ T Cell Responses Despite VaccinationJoshua S. Woodworth, Daniel Sanghoon Shin, Mattijs Volman, Cláudio Nunes-Alves, Sarah M. Fortune, Samuel M. Behar · 2010 · The Journal of Immunology
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- Peptide:MHC Tetramer-based Enrichment of Epitope-specific T cellsFrancois P. Legoux, James J. Moon · 2012 · Journal of Visualized Experiments
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- The Fate Choice Between Effector and Memory T Cell Lineages: Asymmetry, Signal Integration, and Feedback to Create BistabilityRonald A. Backer, Pleun Hombrink, Christina Helbig, Derk Amsen · 2018 · Advances in immunology
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- Understanding CD8+ T‐cell responses toward the native and alternate HLA‐A∗02:01‐restricted WT1 epitopeThi H. O. Nguyen, Amabel C. L. Tan, Sue Dong Xiang, Anne Goubier, Kim L. Harland, E. Bridie Clemens, Magdalena Plebanski, Katherine Kedzierska · 2017 · Clinical & Translational Immunology
- Attrition of T Cell Zone Fibroblastic Reticular Cell Number and Function in Aged SpleensApril R. Masters, Evan R. Jellison, Lynn Puddington, Kamal Mohan Khanna, Laura Haynes · 2018 · ImmunoHorizons
- Vaccine-Induced Boosting of Influenza Virus-Specific CD4 T Cells in Younger and Aged HumansDolfi, Douglas V., Mansfield, Kathleen D., Kurupati, Raj K., Kannan, Senthil, Doyle, Susan A., Ertl, Hildegund C. J., Schmader, Kenneth E., Wherry, E. John · 2013 · PLoS ONE
- The Breadth of Synthetic Long Peptide Vaccine-Induced CD8+ T Cell Responses Determines the Efficacy against Mouse Cytomegalovirus InfectionEleni Panagioti, Anke Redeker, Suzanne van Duikeren, Kees L. M. C. Franken, Jan Wouter Drijfhout, Sjoerd H. van der Burg, Ramon Arens · 2016 · PLoS Pathogens
- Vaccination reshapes the virus-specific T cell repertoire in unexposed adultsYi‐Gen Pan, Benjamas Aiamkitsumrit, Laurent Bartolo, Yifeng Wang, Criswell L. M. Lavery, Adam Marc, Patrick V. Holec, C. Garrett Rappazzo, Theresa Eilola, Phyllis A. Gimotty et al. · 2021 · Immunity
- Divergent Clonal Differentiation Trajectories Establish CD8 + Memory T Cell Heterogeneity During Acute Viral Infections in HumansJeff Eron Mold, Laurent Modolo, Joanna Hård, Margherita Zamboni, Anton J. M. Larsson, Moa Stenudd, Carl‐Johan Eriksson, Ghislain Durif, Patrik L. Ståhl, Erik Borgström et al. · 2020 · Cell Reports
- Signatures of recent activation identify a circulating T cell compartment containing tumor-specific antigen receptors with high avidityAnna Purcarea, Sebastian Jarosch, Jack Barton, Simon A. Grassmann, Ludwig O. Pachmayr, Elvira D’Ippolito, Monika Hammel, Anna Hochholzer, Karolin I. Wagner, Joost H. van den Berg et al. · 2022 · Science Immunology
- A tessellated lymphoid network provides whole-body T cell surveillance in zebrafishTanner Ford Robertson, Yiran Hou, Jonathan H. Schrope, Simone Shen, Julie Rindy, John‐Demian Sauer, Huy Q. Dinh, Anna Huttenlocher A · 2023 · Proceedings of the National Academy of Sciences
- Visualizing T Cell Migration in situAlexandre P. Benechet, Manisha Menon, K. Khanna · 2014 · Frontiers in Immunology
- Antigen‐specific and cross‐reactive T cells in protection and diseaseNing Jenny Jiang, Michael D. Malone, Shahab Chizari · 2023 · Immunological Reviews
- Division of labor between subsets of lymph node dendritic cells determines the specificity of the CD8 + T‐cell recall response to influenza infectionJenny E Suarez-Ramirez, Tao Wu, Young‐Tae Lee, Carolina C. Aguila, Keith R. Bouchard, Linda S. Cauley · 2011 · European Journal of Immunology
- Cross‐presentation of peptides from intracellular pathogens by MHC class I moleculesNicolas Blanchard, Nilabh Shastri · 2010 · Annals of the New York Academy of Sciences
- The Longevity of Memory CD8 T Cell Responses after Repetitive Antigen StimulationsDeepa Rai, Matthew David Martin, Vladimir P. Badovinac · 2014 · The Journal of Immunology
- Immunological Synapses Within Context: Patterns of Cell–Cell Communication and Their Application in T–T InteractionsJunsang Doh, Matthew F. Krummel · 2009 · Current topics in microbiology and immunology
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- Increasing Viral Dose Causes a Reversal in CD8+ T Cell Immunodominance during Primary Influenza Infection due to Differences in Antigen Presentation, T Cell Avidity, and Precursor NumbersFabio Luciani, Megan T. Sanders, Sara Oveissi, Ken C. Pang, Weisan Chen · 2012 · The Journal of Immunology
- Effect of MHC Class I Diversification on Influenza Epitope-Specific CD8+ T Cell Precursor Frequency and Subsequent Effector FunctionE. Bridie Clemens, Kim L. Harland, Nicole L. La Gruta, Peter C. Doherty, Stephen J Turner · 2011 · The Journal of Immunology
- A Numerically Subdominant CD8 T Cell Response to Matrix Protein of Respiratory Syncytial Virus Controls Infection with Limited ImmunopathologyJie Liu, Elias K. Haddad, Joshua Marceau, Kaitlyn M. Morabito, Srinivas S. Rao, Ali Filali‐Mouhim, Rafick‐Pierre Sékaly, Barney S. Graham · 2016 · PLoS Pathogens
- Type I IFN ineffectively activates neonatal dendritic cells limiting respiratory antiviral T-cell responsesAnnie W. Lau-Kilby, Mathilde Turfkruyer, Margaret Kehl, Lijuan Yang, Ursula J. Buchholz, Kimberly W. Hickey, Allison M. W. Malloy · 2019 · Mucosal Immunology
- Analysis of Relationships between Peptide/MHC Structural Features and Naive T Cell Frequency in HumansJean‐Baptiste Reiser, Francois P. Legoux, Stéphanie Gras, Eric Trudel, Anne Chouquet, Alexandra Léger, Madalen Le Gorrec, Paul Machillot, Marc Bonneville, Xavier Saulquin et al. · 2014 · The Journal of Immunology
- IL4I1 Accelerates the Expansion of Effector CD8+ T Cells at the Expense of Memory Precursors by Increasing the Threshold of T-Cell ActivationMarie‐Line Puiffe, Aurélie Dupont, Nouhoum Sako, Jérôme Gatineau, José Laurent Cohen, Denis Mestivier, Agnès Le Bon, Armelle Prévost‐Blondel, Flavia Castellano, Valérie Molinier‐Frenkel · 2020 · Frontiers in Immunology
- RasGRP1 Regulates Antigen-Induced Developmental Programming by Naive CD8 T CellsJohn J. Priatel, Xiaoxi Chen, Yu‐Hsuan Huang, Michael Chow, Lauren A. Zenewicz, Jason J. Coughlin, Hao Shen, James C. Stone, Rusung Tan, Hung‐Sia Teh · 2009 · The Journal of Immunology
- Cis-Acting Pathways Selectively Enforce the Non-Immunogenicity of Shed Placental Antigen for Maternal CD8 T CellsChin-Siean Tay, Elisa Tagliani, Mary K. Collins, Adrian Erlebacher · 2013 · PLoS ONE
- Evaluation of cellular immune responses in cancer vaccine recipients: lessons from NY-ESO-1Jonathan Simon Cebon, Ashley J. Knights, Lisa M. Ebert, Heather M. Jackson, Weisan Chen · 2010 · Expert Review of Vaccines
- Antigen-specific T cells and autoimmunityManuel Rojas, Yeny Acosta‐Ampudia, Luke S. Heuer, Weici Zang, Diana M. Monsalve, Carolina Ramı́rez-Santana, Juan‐Manuel Anaya, William M. Ridgway, Aftab Ahmed Ansari, M. Eric Gershwin · 2024 · Journal of Autoimmunity
- Principles of Memory CD8 T-Cells Generation in Relation to Protective ImmunityMaurizio Zanetti, Paola Castiglioni, Elizabeth G. Ingulli · 2010 · Advances in experimental medicine and biology
- Efficiency of Dendritic Cell Vaccination against B16 Melanoma Depends on the Immunization RouteFanny Edele, Jan C. Dudda, Eva Bachtanian, Thilo Jakob, Hanspeter Pircher, Stefan F. Martin · 2014 · PLoS ONE
- What’s self got to do with it: Sources of heterogeneity among naive T cellsSébastien This, Dakota Rogers, Ève Mallet Gauthier, Judith N. Mandl, Heather J. Melichar · 2022 · Seminars in Immunology
- Time and Antigen-Stimulation History Influence Memory CD8 T Cell Bystander ResponsesMatthew David Martin, Qiang Shan, Hai‐Hui Xue, Vladimir P. Badovinac · 2017 · Frontiers in Immunology
- Increased Memory Conversion of Naïve CD8 T Cells Activated during Late Phases of Acute Virus Infection Due to Decreased Cumulative Antigen ExposureGeorgia Fousteri, Amy Dave, Amy E. Juedes, Therese Juntti, Bret Morin, Lisa M. Togher, Donna L. Färber, Matthias von Herrath · 2011 · PLoS ONE
- CD8+ T cell immunodominance shifts during the early stages of acute LCMV infection independently from functional avidity maturationHans-Peter Raué, Mark K. Slifka · 2009 · Virology
- Extrinsic and intrinsic drivers of natural killer cell clonalityTimo Rückert, Chiara Romagnani · 2024 · Immunological Reviews
- The endogenous antigen-specific CD8+ T cell repertoire is composed of unbiased and biased clonotypes with differential fate commitmentsLeena Abdullah, Francesco E. Emiliani, Chinmay Vaidya, Hannah Stuart, Shawn C. Musial, Fred Kolling, Joshua J. Obar, Pamela C. Rosato, Margaret E. Ackerman, Song Li et al. · 2025 · Immunity
- Zfp36l1 establishes the high‐affinity CD8 T‐cell response by directly linking TCR affinity to cytokine sensingGeorg Petkau, Twm J. Mitchell, Marian Jones Evans, Louise S. Matheson, Fiamma Salerno, Martin Turner · 2023 · European Journal of Immunology
- In vivo RNAi screens: concepts and applicationsShane Crotty, Matthew E. Pipkin · 2015 · Trends in Immunology
- Clonally Expanded Virus-Specific CD8 T Cells Acquire Diverse Transcriptional Phenotypes During Acute, Chronic, and Latent InfectionsRaphael Kuhn, Ioana Sandu, Andreas Agrafiotis, Kai‐Lin Hong, Danielle Shlesinger, Daniel Neimeier, Doron Merkler, Annette Oxenius, Sai T. Reddy, Alexander Yermanos · 2022 · Frontiers in Immunology
- Differential requirements of CD 4+ T ‐cell signals for effector cytotoxic T‐lymphocyte ( CTL ) priming and functional memory CTL development at higher CD 8+ T ‐cell precursor frequencyChannakeshava Sokke Umeshappa, Roopa Hebbandi Nanjundappa, Yufeng Xie, Andrew Freywald, Qingyong Xu, Jim Xiang · 2012 · Immunology
- A new mechanism shapes the naïve CD8+ T cell repertoire: the selection for full diversityPedro Gonçalves, Marco Ferrarini, Carmen Molina-Parı́s, Grant Lythe, Florence Vasseur, Annik Lim, Bénédita Rocha, Orly Azogui · 2017 · Molecular Immunology
- Co‐expression of HLA ‐ B 7 and HLA ‐ B 27 alleles is associated with B 7‐restricted immunodominant responses following influenza infectionAli Akram, Robert Davies Inman · 2013 · European Journal of Immunology
- Antecedent Administration of Glutamine Benefits the Homeostasis of CD4+ T Cells and Attenuates Lung Injury in Mice With Gut‐Derived Polymicrobial SepsisCing‐Syuan Lei, Jin‐Ming Wu, Po‐Chu Lee, Ting‐Chun Kuo, Po‐Da Chen, Yu‐Chen Hou, Sung‐Ling Yeh, Ming‐Tsan Lin · 2019 · Journal of Parenteral and Enteral Nutrition
- A novel T‐cell receptor mimic defines dendritic cells that present an immunodominant West Nile virus epitope in miceSojung Kim, Amelia K. Pinto, Nancy B. Myers, Oriana E. Hawkins, Krysten L. Doll, Saghar Kaabinejadian, Jason Netland, Michael J. Bevan, Jon A. Weidanz, William H. Hildebrand et al. · 2014 · European Journal of Immunology
- Shaping the T‐cell repertoire in the peripheryStacey M. Allen, Stephen J Turner, Dorothée Bourges, Paul A. Gleeson, Ian Richard van Driel · 2010 · Immunology and Cell Biology
- New approaches to design HIV-1 T-cell vaccinesHélène Perrin, Glenda Canderan, Rafick‐Pierre Sékaly, Lydie Trautmann · 2010 · Current Opinion in HIV and AIDS
- Respiratory Virus VaccinesAndrew Broadbent, Kobporn Boonnak, Kanta Subbarao · 2015 · Elsevier eBooks
- T Cell Receptor Diversity and Lineage Relationship between Virus-Specific CD8 T Cell Subsets during Chronic Lymphocytic Choriomeningitis Virus InfectionDaniel Y. Chang, Andreas Wieland, Zheng-Rong Tiger Li, Se Jin Im, Donald J. McGuire, Haydn Thomas Kissick, Rustom Antia, Rafi Ahmed · 2020 · Journal of Virology
- Influence of time and number of antigen encounters on memory CD8 T cell developmentMatthew David Martin, Vladimir P. Badovinac · 2014 · Immunologic Research
- Vaccination-induced T cell responses maintain polyclonality with high antigen receptor avidityKatharina Kocher, Felix Drost, Abel Mekonnen Tesfaye, Carolin Moosmann, Christine Schülein, Myriam Grotz, Elvira D’Ippolito, Frederik Graw, Bernd M. Spriewald, Dirk Hans Busch et al. · 2025 · Science Immunology
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- Modification of a Tumor Antigen Determinant To Improve Peptide/MHC Stability Is Associated with Increased Immunogenicity and Cross-Priming a Larger Fraction of CD8+ T CellsAlan M. Watson, Lawrence M. Mylin, Megan M Thompson, Todd D. Schell · 2012 · The Journal of Immunology
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- CD40 ligand‐expressing recombinant vaccinia virus promotes the generation of CD8+ central memory T cellsEmanuele Trella, Nermin Raafat, Chantal Mengus, Emmanuel Traunecker, Valeria Governa, Swantje Heidtmann, Michael Heberer, Daniel Oertli, Giulio C. Spagnoli, Paul Zajac · 2015 · European Journal of Immunology
- CD8+ T cell self-tolerance permits responsiveness but limits tissue damageEmily Nestor Truckenbrod, Kristina S. Burrack, Todd Philip Knutson, Henrique Borges da Silva, Katharine E. Block, Stephen D. O’Flanagan, Katie R Stagliano, Arthur A. Hurwitz, Ross Bane Fulton, Kristin R. Renkema et al. · 2021 · eLife
- Altered decamer and nonamer from an HLA-A0201-restricted epitope of Survivin differentially stimulate T-cell responses in different individualsChantale Bernatchez, Kuichun Zhu, Yufeng Li, H. Andersson, Constantin Ionnides, Marcelo Fernández-Viña, Pedro Cano, Laurence J.N. Cooper, James L. Abbruzzese, Patrick Hwu et al. · 2011 · Vaccine
- High initial frequency of TCR-transgenic CD8 T cells alters inflammation and pathogen clearance without affecting memory T cell functionThomas Christian Wirth, Nhat-Long L. Pham, John T. Harty, Vladimir P. Badovinac · 2009 · Molecular Immunology
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- Epitope Specificity and Relative Clonal Abundance Do Not Affect CD8 Differentiation Patterns during Lymphocytic Choriomeningitis Virus InfectionIvana Munitić, Hélène Decaluwe, César Evaristo, Sara Lemos, Myriam F. Wlodarczyk, Andrew T. Worth, Agnès Le Bon, Liisa Kaarina Selin, Yves Rivière, James P. Di Santo et al. · 2009 · Journal of Virology
- Extent of Systemic Spread Determines CD8+ T Cell Immunodominance for Laboratory Strains, Smallpox Vaccines, and Zoonotic Isolates of Vaccinia VirusInge E. A. Flesch, Natasha A. Hollett, Yik Chun Wong, Bárbara Resende Quinan, Debbie R. Howard, Flávio Guimarães da Fonseca, David C. Tscharke · 2015 · The Journal of Immunology
- Drug and Chemical Allergy: A Role for a Specific Naive T-Cell Repertoire?Rami Bechara, Alexia Feray, Marc J. Pallardy · 2021 · Frontiers in Immunology
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- Elevated Tumor-Associated Antigen Expression Suppresses Variant Peptide Vaccine ResponsesCharles B. Kemmler, Eric T. Clambey, Ross M. Kedl, Jill E. Slansky · 2011 · The Journal of Immunology
- Immunodominance of HLA-B27-restricted HIV KK10-specific CD8+ T-cells is not related to naïve precursor frequencyMaría Candela Iglesias, Olivia Briceño, Emma Gostick D, Arnaud Moris, Céline Meaudre, David A. Price, Marie‐Noëlle Ungeheuer, Asier Sáez‐Cirión, Roberto Mallone, Victor Appay · 2012 · Immunology Letters
- Effector Function-Deficient Memory CD8+ T Cells Clonally Expand in the Liver and Give Rise to Peripheral Memory CD8+ T CellsYu‐Chia Su, Chen-Cheng Lee, John T. Kung · 2010 · The Journal of Immunology
- To Remember or to Forget: The Role of Good and Bad Memories in Adoptive T Cell Therapy for TumorsAnna Mondino, Teresa Manzo · 2020 · Frontiers in Immunology
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