CDK8 Kinase Phosphorylates Transcription Factor STAT1 to Selectively Regulate the Interferon Response

Bancerek, Joanna, Poss, Zachary C., Steinparzer, Iris, Sedlyarov, Vitaly, Pfaffenwimmer, Thaddäus, Mikulic, Ivana, Dölken, Lars, Strobl, Birgit +3 more·2013·Immunity

Cited by (311)

Items 301–311 of 311

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  3. BindingDB Entry 50022813: Design and synthesis of 7-azaindole derivatives as potent CDK8 inhibitors for the treatment of acute myeloid leukemia.
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  4. BindingDB Entry 50021065: Discovery of a Novel and Potent Cyclin-Dependent Kinase 8/19 (CDK8/19) Inhibitor for the Treatment of Cancer.
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  5. BindingDB Entry 50047467: Development of a Potent, Specific CDK8 Kinase Inhibitor Which Phenocopies CDK8/19 Knockout Cells.
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  6. BindingDB Entry 50007322: Shape-based virtual screen for the discovery of novel CDK8 inhibitor chemotypes.
    BindingDB · 2021 · UC San Diego
  7. BindingDB Entry 50013361: Pyrido[2,3-b][1,5]benzoxazepin-5(6H)-one derivatives as CDK8 inhibitors.
    BindingDB · 2022 · UC San Diego
  8. BindingDB Entry 50000384: Design and synthesis of selective CDK8/19 dual inhibitors: Discovery of 4,5-dihydrothieno[3',4':3,4]benzo[1,2-d]isothiazole derivatives.
    BindingDB · 2019 · UC San Diego
  9. BindingDB Entry 50000167: Studies of CDK 8/19 inhibitors: Discovery of novel and selective CDK8/19 dual inhibitors and elimination of their CYP3A4 time-dependent inhibition potential.
    BindingDB · 2019 · UC San Diego
  10. BindingDB Entry 50018624: Angel or Devil ? - CDK8 as the new drug target.
    BindingDB · 2024 · UC San Diego
  11. BindingDB Entry 50009833: Design and Development of a Series of Potent and Selective Type II Inhibitors of CDK8.
    BindingDB · 2021 · UC San Diego