A Death Notice for In-Vitro-Generated GM-CSF Dendritic Cells?
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Mouse bone marrow cells cultured with GM-CSF are often used to generate dendritic cells (DCs); in this issue of Immunity, Helft et al. (2015) show that this classical method produces heterogeneous populations of myeloid cells that are only distantly related to macrophages and DCs found in vivo.
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Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny
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Self-citationSingle-cell transcriptomics reveals bimodality in expression and splicing in immune cells
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Aran, D., Looney, A. P., Liu, L., Wu, E., Fong, V., Hsu, A., Chak, S., Naikawadi, R. P., Wolters, P. J., Abate, A. R., et al. (2019) · Nature Immunology · doi:10.1038/s41590-018-0276-y · Cited by 4,984 · see citing works
Cabeza-Cabrerizo, M., Cardoso, A., Minutti, C. M., Pereira da Costa, M., & Reis e Sousa, C. (2021) · Annual Review of Immunology · doi:10.1146/annurev-immunol-061020-053707 · Cited by 757 · see citing works
- Authors
- Guilliams, M., & Malissen, B.
- Affiliations
- VIB-UGent Center for Inflammation Research (BE)
- Centre National de la Recherche Scientifique (FR)
- Corresponding author
- Guilliams, Martin
- Malissen, Bernard
- Venue
- Immunity
- Publisher
- Elsevier BV
- Published
- 2015-06
- Volume
- 42
- Issue
- 6
- Pages
- 988-990
- ISSN
- 1074-7613 (ISSN-L)
- OpenAlex
- W1608557965
- Cited by
- 38
- References
- 10
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 1 · 2023: 1 · 2022: 1 · 2021: 5 · 2020: 6 · 2019: 8 · 2018: 1 · 2017: 3 · 2016: 5 · 2015: 2
- FWCI
- 1.81
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Immunity (publishedVersion)
- PubMed (publishedVersion)
- Ghent University Academic Bibliography (Ghent University) (submittedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Immunotherapy and Immune Responses
- Life Sciences › Immunology and Microbiology › Immunology › Immune responses and vaccinations
- Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
- Keywords
- dendritic cells, GM-CSF, bone marrow cells, myeloid heterogeneity, macrophages, dendritic cell differentiation
- MeSH terms
- Animals, Bone Marrow Cells, Dendritic Cells, Macrophages
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