The DOI matches its Crossref record; 171 of the 171 references it cites were found in a registry or an index.
The immunology of sepsis
Open accessAbstract
Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to an infection. This recently implemented definition does not capture the heterogeneity or the underlying pathophysiology of the syndrome, which is characterized by concurrent unbalanced hyperinflammation and immune suppression. Here, we review current knowledge of aberrant immune responses during sepsis and recent initiatives to stratify patients with sepsis into subgroups that are more alike from a clinical and/or pathobiological perspective, which could be key for identification of patients who are more likely to benefit from specific immune interventions.
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Cites
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Cited by
GPX4, ferroptosis, and diseases
Zhang, W., Liu, Y., Liao, Y., Zhu, C., & Zou, Z. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116512 · Cited by 426
Immunopathophysiology of human sepsis
Wiersinga, W. J., & van der Poll, T. (2022) · eBioMedicine · doi:10.1016/j.ebiom.2022.104363 · Cited by 322
Self-citationCytokine Storm—Definition, Causes, and Implications
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Jin, N., Nan, C., Li, W., Lin, P., Xin, Y., Wang, J., Chen, Y., Wang, Y., Yu, K., Wang, C., et al. (2024) · Briefings in Bioinformatics · doi:10.1093/bib/bbae661 · Cited by 9
Metadata
- Authors
- van der Poll, T., Shankar-Hari, M., & Wiersinga, W. J.
- Venue
- Immunity
- Publisher
- Elsevier BV
- Published
- 2021-11
- Volume
- 54
- Issue
- 11
- Pages
- 2450-2464
- ISSN
- 1074-7613 (ISSN-L)
- OpenAlex
- W3214720083
- Cited by
- 1,010
- References
- 171
- FWCI
- 76.44
- Type
- journal article
- Language
- en
- Open access
- bronze
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- van der Poll, T., Shankar-Hari, M., & Wiersinga, W. J. (2021). The immunology of sepsis. Immunity. https://doi.org/10.1016/j.immuni.2021.10.012
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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