The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.
Cryopreservation and its clinical applications
Open accessAbstract
Cryopreservation is a process that preserves organelles, cells, tissues, or any other biological constructs by cooling the samples to very low temperatures. The responses of living cells to ice formation are of theoretical interest and practical relevance. Stem cells and other viable tissues, which have great potential for use in basic research as well as for many medical applications, cannot be stored with simple cooling or freezing for a long time because ice crystal formation, osmotic shock, and membrane damage during freezing and thawing will cause cell death. The successful cryopreservation of cells and tissues has been gradually increasing in recent years, with the use of cryoprotective agents and temperature control equipment. Continuous understanding of the physical and chemical properties that occur in the freezing and thawing cycle will be necessary for the successful cryopreservation of cells or tissues and their clinical applications. In this review, we briefly address representative cryopreservation processes, such as slow freezing and vitrification, and the available cryoprotective agents. In addition, some adverse effects of cryopreservation are mentioned.
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Citations
Cites
Revival of Spermatozoa after Vitrification and Dehydration at Low Temperatures
POLGE, C., SMITH, A. U., & PARKES, A. S. (1949) · Nature · doi:10.1038/164666a0 · Cited by 2,081
Ice-free cryopreservation of mouse embryos at −196 °C by vitrification
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Mazur, P. (1970) · Science · doi:10.1126/science.168.3934.939 · Cited by 1,402
A two-factor hypothesis of freezing injury
Mazur, P., Leibo, S. P., & Chu, E. H. Y. (1972) · Experimental Cell Research · doi:10.1016/0014-4827(72)90303-5 · Cited by 969
Prevention of Freezing Damage to Living Cells by Dimethyl Sulphoxide
LOVELOCK, J. E., & BISHOP, M. W. H. (1959) · Nature · doi:10.1038/1831394a0 · Cited by 966
Protectants used in the cryopreservation of microorganisms
Hubálek, Z. (2003) · Cryobiology · doi:10.1016/s0011-2240(03)00046-4 · Cited by 790
Long-term storage of tissues by cryopreservation: critical issues
Karlsson, J. O. M., & Toner, M. (1996) · Biomaterials · doi:10.1016/0142-9612(96)85562-1 · Cited by 619
Principles of Cryopreservation
Pegg, D. E. (2007) · Methods in Molecular Biology · doi:10.1007/978-1-59745-362-2_3 · Cited by 604
Mechanisms of Cryoinjury in Living Cells
Gao, D., & Critser, J. K. (2000) · ILAR Journal · doi:10.1093/ilar.41.4.187 · Cited by 533
Cryoprotectant Toxicity: Facts, Issues, and Questions
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Cited by
Ice Inhibition for Cryopreservation: Materials, Strategies, and Challenges
Chang, T., & Zhao, G. (2021) · Advanced Science · doi:10.1002/advs.202002425 · Cited by 419
Cryopreservation: An Overview of Principles and Cell-Specific Considerations
Whaley, D., Damyar, K., Witek, R. P., Mendoza, A., Alexander, M., & Lakey, J. R. (2021) · Cell Transplantation · doi:10.1177/0963689721999617 · Cited by 403
Messner, F., Guo, Y., Etra, J. W., & Brandacher, G. (2019) · Transplant International · doi:10.1111/tri.13432 · Cited by 29
Metadata
- Authors
- Jang, T. H., Park, S. C., Yang, J. H., Kim, J. Y., Seok, J. H., Park, U. S., Choi, C. W., Lee, S. R., & Han, J.
- Venue
- Integrative Medicine Research
- Publisher
- Elsevier BV
- Published
- 2017-03
- Volume
- 6
- Issue
- 1
- Pages
- 12-18
- ISSN
- 2213-4220 (ISSN-L)
- OpenAlex
- W2571352594
- Cited by
- 485
- References
- 39
- FWCI
- 22.86
- Type
- journal article
- Language
- en
- Open access
- gold
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- Jang, T. H., Park, S. C., Yang, J. H., Kim, J. Y., Seok, J. H., Park, U. S., Choi, C. W., Lee, S. R., & Han, J. (2017). Cryopreservation and its clinical applications. Integrative Medicine Research. https://doi.org/10.1016/j.imr.2016.12.001
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
