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Cited by 110Medicinal Plant ResearchPhytochemistry and biological activity of medicinal plantsPhytochemicals and Medicinal Plants

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Lawsonia inermis L. – A commercially important primaeval dying and medicinal plant with diverse pharmacological activity: A review

Singh, Dhananjay Kumar, Luqman, Suaib, Mathur, Ajay Kumar·2015·Industrial Crops and Products
DOI 10.1016/j.indcrop.2014.11.025
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Abstract

Lawsonia inermis, popularly known as Henna or Mehndi in the Oriental world, is an evergreen medium sized shrub of the Family Lythraceae. The leaf paste of this plant has been traditionally used for dying hair, skin and nails since antiquity. Besides cosmaceutical usages, the plant also harbours a well-documented folklore history for treating convulsion, jaundice and malignant ulcers. Phytochemical studies in henna plant have indicated the presence of several bioactive molecules like isoplumpagin, lupeol, 30-norlupan-3-ol-20-one, betuhennan, betuhennanic acid and n-tridecanoate phenolic glycosides, lawsoniaside, β-sitosterol and stigmasterol in leaves and roots. Lawsone (2-hydroxy-1,4-naphthoquinone), the red orange dye present in the henna leaf paste, is being used in modern pharmacopoeia as a starting molecule for the synthesis of clinically important anticancer drugs such as atovaquone, lapachol and dichloroallyl lawsone. Pharmacological prospection of L. inermis plant extracts in last two decades have indicated strong nootropic, CNS depressing, antimicrobial, antioxidant, wound healing, anti-inflammatory, antipyretic, analgesic, hepatoprotective, tuberculostatic, diuretic, hypoglycemic and antiparasitic actions. An attempt has been made in this review to accentuate a comprehensive literature up-date on pharmacological investigations carried out in L. inermis. To the best of our knowledge and belief this is the first compilation in this direction in Henna.

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Metadata

Authors
Singh, D. K., Luqman, S., & Mathur, A. K.
Affiliations
  • Central Institute of Medicinal and Aromatic Plants (IN)
  • Council of Scientific and Industrial Research (IN)
Corresponding author
Luqman, Suaib
ORCID
Luqman, Suaib
Venue
Industrial Crops and Products
Publisher
Elsevier BV
Published
2015-03
Volume
65
Pages
269-286
ISSN
0926-6690 (ISSN-L)
DOI
10.1016/j.indcrop.2014.11.025
OpenAlex
W2034734627
Cited by
110
References
1
Citations by year
2026: 7 · 2025: 12 · 2024: 7 · 2023: 20 · 2022: 9 · 2021: 17 · 2020: 4 · 2019: 9 · 2018: 12 · 2017: 5 · 2016: 6 · 2015: 1
FWCI
4.67
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
Industrial Crops and Products (publishedVersion)
Funders
  • CSIR
  • Council of Scientific and Industrial Research, New Delhi
Topics
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry and biological activity of medicinal plants
  • Health Sciences › Medicine › Complementary and alternative medicine › Phytochemicals and Medicinal Plants
Keywords
Lawsonia inermis, lawsone, Lythraceae, medicinal plants, phytochemistry, lupeol, β-sitosterol, stigmasterol, pharmacological activity, antimicrobial activity, antioxidant activity, wound healing, anti-inflammatory activity, hepatoprotection, antiparasitic activity, anticancer agents, hair dyeing, traditional medicine

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