RETRACTED: The protective role of microRNA-133b in restricting hippocampal neurons apoptosis and inflammatory injury in rats with depression by suppressing CTGF
Abstract
This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief. Concern was raised about the integrity of the images in Figures 5, 6A and 8A, which appear to contain suspected duplications, as detailed here: https://pubpeer.com/publications/773D824533241B2186D16AA3FFCB3F and here: https://docs.google.com/spreadsheets/d/1r0MyIYpagBc58BRF9c3luWNlCX8VUvUuPyYYXzxWvgY/edit#gid=262337249. Additional suspected image duplications were detected within Figure 7A. Our analysis suggested these image anomalies represent either direct duplications of the entire image, or contain several repeated features between or within an image. The journal requested the corresponding author comment on these concerns and provide the raw data. The authors did not respond to this request and therefore the Editor-in-Chief decided to retract the article.
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The retraction was requested by the journal's Editor-in-Chief after they unsuccessfully sought an explanation from the purported authors.
“The retraction was requested by the journal's Editor-in-Chief, after they had unsuccessfully sought the (purported) authors for an explanation 42 .”
From Fraudulent studies are undermining the reliability of systematic reviews: on the prevalence of problematic images in preclinical depression studies (2025) · cites this paper as [42]
Cites
Slavich, G. M., & Irwin, M. R. (2014) · Psychological Bulletin · doi:10.1037/a0035302 · Cited by 2,206 · see citing works
Exercise as a treatment for depression: a meta-analysis adjusting for publication bias
Schuch, F. B., Vancampfort, D., Richards, J., Rosenbaum, S., Ward, P. B., & Stubbs, B. (2016) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2016.02.023 · Cited by 1,529 · see citing works
Chronic Insomnia as a Risk Factor for Developing Anxiety and Depression
Neckelmann, D., Mykletun, A., & Dahl, A. A. (2007) · Sleep · doi:10.1093/sleep/30.7.873 · Cited by 665 · see citing works
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MicroRNAs as critical biomarkers of major depressive disorder: a comprehensive perspective
Ortega, M. A., Alvarez-Mon, M. A., García-Montero, C., Fraile-Martinez, O., Lahera, G., Monserrat, J., Muñoz-Merida, L., Mora, F., Rodríguez-Jiménez, R., Fernandez-Rojo, S., et al. (2021) · Biomedicines · doi:10.3390/biomedicines9111659 · Cited by 57 · see citing works
Wu, W., Cao, X., & Wang, Y. (2022) · Genes & Genomics · doi:10.1007/s13258-021-01171-3 · Cited by 4 · see citing works
Berrío, J. P., & Kalliokoski, O. (2025) · FEBS Letters · doi:10.1002/1873-3468.70077 · Cited by 7 · see citing works
- Authors
- Pei, G., Xu, L., Huang, W., & Yin, J.
- Affiliations
- Second Affiliated Hospital of Zhengzhou University (CN)
- Corresponding author
- Yin, Jianjun
- Venue
- International Immunopharmacology
- Publisher
- Elsevier BV
- Published
- 2020-01
- Volume
- 78
- Pages
- 106076
- ISSN
- 1567-5769 (ISSN-L)
- OpenAlex
- W2996741514
- Cited by
- 26
- References
- 3
- Citations by year
- 2024: 1 · 2023: 3 · 2022: 12 · 2021: 7 · 2020: 3
- FWCI
- 3.41
- Type
- journal article
- Language
- en
- Status
- Retracted
- Open access
- closed
- Locations
- International Immunopharmacology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › MicroRNA in disease regulation
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Keywords
- microRNA-133b, connective tissue growth factor, hippocampal neurons, neuronal apoptosis, neuroinflammation, depression, image duplication, retraction
- MeSH terms
- Animals, Depression, Disease Models, Animal, Hippocampus, Humans, Inflammation, Male, Neurons, Stress, Psychological, Apoptosis, MicroRNAs, Rats, Connective Tissue Growth Factor, Disease Resistance
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