Catecholamine modulators: lessons from nonhuman primates
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The optimal dose of atomoxetine varied widely, which may explain variability of drug response in patients.
“Interestingly, the optimal dose varied widely, which may explain variability of drug response in patients (Castellanos and Kelly, 2010).”
From Catecholamine influences on prefrontal cortical function: Relevance to treatment of attention deficit/hyperactivity disorder and related disorders (2011) · cites this paper as Castellanos and Kelly, 2010
Cites
The relation of strength of stimulus to rapidity of habit formation
Yerkes, R. M., & Dodson, J. D. (1908) · Journal of Comparative Neurology and Psychology · doi:10.1002/cne.920180503 · Cited by 6,911 · see citing works
Neuroscience of attention-deficit/hyperactivity disorder: the search for endophenotypes
Castellanos, F. X., & Tannock, R. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn896 · Cited by 1,827 · see citing works
Self-citationTHE BEHAVIOR OF CHILDREN RECEIVING BENZEDRINE
Bradley, C. (1937) · American Journal of Psychiatry · doi:10.1176/ajp.94.3.577 · Cited by 1,035 · see citing works
Inverted-U dopamine D1 receptor actions on prefrontal neurons engaged in working memory
Vijayraghavan, S., Wang, M., Birnbaum, S. G., Williams, G. V., & Arnsten, A. F. T. (2007) · Nature Neuroscience · doi:10.1038/nn1846 · Cited by 1,013 · see citing works
Sonuga-Barke, E. J. S., & Castellanos, F. X. (2007) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2007.02.005 · Cited by 890 · see citing works
Self-citationKey role of coupling, delay, and noise in resting brain fluctuations
Deco, G., Jirsa, V., McIntosh, A. R., Sporns, O., & Kötter, R. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0901831106 · Cited by 756 · see citing works
Stochastic dynamics as a principle of brain function
Deco, G., Rolls, E. T., & Romo, R. (2009) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2009.01.006 · Cited by 382 · see citing works
Gamo, N. J., Wang, M., & Arnsten, A. F. T. (2010) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2010.06.015 · Cited by 232 · see citing works
Stimulant drugs and ADHD : basic and clinical neuroscience
Solanto, M. V., Arnsten, A. F. T., & Castellanos, F. X. (2001) · Cited by 223 · see citing works
Self-citationFrom the Inverted-U to the Extended-U: The Evolution of a Law of Psychology
Hancock, P. A., & Ganey, H. C. N. (2003) · Human performance in extreme environments · doi:10.7771/2327-2937.1023 · Cited by 89 · see citing works
The Loss of Serendipity in Psychopharmacology
Klein, D. F. (2008) · JAMA · doi:10.1001/jama.299.9.1063 · Cited by 82 · see citing works
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Sharma, A., & Couture, J. (2014) · Annals of Pharmacotherapy · doi:10.1177/1060028013510699 · Cited by 516 · see citing works
Arnsten, A. F. T., & Pliszka, S. R. (2011) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2011.01.020 · Cited by 383 · see citing works
- Authors
- Castellanos, F. X., & Kelly, C.
- Affiliations
- Nathan Kline Institute for Psychiatric Research (US)
- NYU Langone Health (US)
- Corresponding author
- Castellanos, F. Xavier
- Venue
- Journal of the American Academy of Child & Adolescent Psychiatry
- Publisher
- Elsevier BV
- Published
- 2010-10
- Volume
- 49
- Issue
- 10
- Pages
- 977-979
- ISSN
- 0890-8567 (ISSN-L)
- OpenAlex
- W2025872919
- Cited by
- 2
- References
- 11
- Citations by year
- 2013: 1
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the American Academy of Child & Adolescent Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Keywords
- attention deficit hyperactivity disorder, methylphenidate, atomoxetine, alpha2-adrenoceptors, dopamine D1 receptor, prefrontal function, non-human primates, translational research, psychopharmacology, fragile X syndrome, autism spectrum disorder
- MeSH terms
- Central Nervous System Stimulants, Animals, Attention Deficit Disorder with Hyperactivity, Catecholamines, Disease Models, Animal, Humans, Prefrontal Cortex, Adrenergic Uptake Inhibitors
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