The DOI matches its Crossref record; 114 of the 114 references it cites were found in a registry or an index.
A Meta-Analysis of Maternal Prenatal Depression and Anxiety on Child Socioemotional Development
Open accessAbstract
OBJECTIVE Observed associations between maternal prenatal stress and children's socioemotional development have varied widely in the literature. The objective of the current study was to provide a synthesis of studies examining maternal prenatal anxiety and depression and the socioemotional development of their children. METHOD Eligible studies through to February 2018 were identified using a comprehensive search strategy. Included studies examined the association between maternal prenatal depression or anxiety and the future development of their children's socioemotional development (eg, difficult temperament, behavioral dysregulation) up to 18 years later. Two independent coders extracted all relevant data. Random-effects meta-analyses were used to derive mean effect sizes and test for potential moderators. RESULTS A total of 71 studies met full inclusion criteria for data analysis. The weighted average effect size for the association between prenatal stress and child socioemotional problems was as follows: odds ratio (OR) = 1.66 (95% CI = 1.54-1.79). Effect sizes were stronger for depression (OR = 1.79; 95% CI = 1.61-1.99) compared to anxiety (OR = 1.50; 95% CI = 1.36-1.64). Moderator analyses indicated that effect sizes were stronger when depression was more severe and when socio-demographic risk was heightened. CONCLUSION Findings suggest that maternal prenatal stress is associated with offspring socioemotional development, with the effect size for prenatal depression being more robust than for anxiety. Mitigating stress and mental health difficulties in mothers during pregnancy may be an effective strategy for reducing offspring behavioral difficulties, especially in groups with social disadvantage and greater severity of mental health difficulties.
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“…brain additionally is particularly susceptible to harm from teratogenic factors such as toxins, infection, maternal stress including prenatal mental health problems, and other environmental exposures (Davis, Head, Buss, & Sandman 2017; Davis et al., 2019; Kim et al., 2017; Madigan et al., 2018).”
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Pharmacotherapy of Postpartum Depression: Current Approaches and Novel Drug Development
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Metadata
- Authors
- Madigan, S., Oatley, H., Racine, N., Fearon, R. M. P., Schumacher, L., Akbari, E., Cooke, J. E., & Tarabulsy, G. M.
- Venue
- Journal of the American Academy of Child & Adolescent Psychiatry
- Publisher
- Elsevier BV
- Published
- 2018-09
- Volume
- 57
- Issue
- 9
- Pages
- 645-657.e8
- ISSN
- 0890-8567 (ISSN-L)
- OpenAlex
- W2884445590
- Cited by
- 448
- References
- 114
- FWCI
- 8.77
- Type
- journal article
- Language
- en
- Open access
- green
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
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- Madigan, S., Oatley, H., Racine, N., Fearon, R. M. P., Schumacher, L., Akbari, E., Cooke, J. E., & Tarabulsy, G. M. (2018). A Meta-Analysis of Maternal Prenatal Depression and Anxiety on Child Socioemotional Development. Journal of the American Academy of Child & Adolescent Psychiatry. https://doi.org/10.1016/j.jaac.2018.06.012
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