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Coronary Heart Disease Mortality Among Young Adults in the U.S. From 1980 Through 2002
Open accessAbstract
Objectives The objective of our study was to examine age-specific mortality rates from coronary heart disease (CHD), particularly those among younger adults.Background Trends for obesity, diabetes, blood pressure, and metabolic syndrome among young adults raise concerns about the mortality rates from CHD in this group.Methods We used mortality data from 1980 to 2002 to calculate age-specific mortality rates from CHD for U.S. adults age > or =35 years.Results Overall, the age-adjusted mortality rate decreased by 52% in men and 49% in women. Among women age 35 to 54 years, the estimated annual percentage change (EAPC) in mortality was -5.4% (95% confidence interval [CI] -5.8 to -4.9) from 1980 until 1989, -1.2% (95% CI -1.6 to -0.8) from 1989 until 2000, and 1.5% (95% CI -3.4 to 6.6) from 2000 until 2002. Among men age 35 to 54 years, the EAPC in mortality was -6.2% (95% CI -6.4 to -5.9) from 1980 until 1989, -2.3% (95% CI -2.6 to -2.1) from 1989 until 2000, and -0.5% (95% CI -3.7 to 2.9) from 2000 until 2002. Among women and men age > or =55 years, the estimated annual percentage decrease in mortality from CHD accelerated in more recent years compared with earlier periods.Conclusions The mortality rates for CHD among younger adults may serve as a sentinel event. Unfavorable trends in several risk factors for CHD provide a likely explanation for the observed mortality rates.
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“This pattern may have changed, and results from recent reports do suggest that mortality and morbidity from CHD is levelling, especially in younger adults.17,18”
From European Guidelines on cardiovascular disease prevention in clinical practice (version 2012) (2012) · cites this paper as [17]
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Metadata
- Authors
- Ford, E. S., & Capewell, S.
- Affiliations
- Centers for Disease Control and Prevention (US)
- University of Liverpool (GB)
- Corresponding author
- Ford, Earl S.
- ORCID
- Capewell, Simon
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 2007-11
- Volume
- 50
- Issue
- 22
- Pages
- 2128-2132
- ISSN
- 0735-1097 (ISSN-L)
- OpenAlex
- W2099693424
- Cited by
- 589
- References
- 31
- Citations by year
- 2026: 5 · 2025: 7 · 2024: 13 · 2023: 17 · 2022: 23 · 2021: 24 · 2020: 29 · 2019: 18 · 2018: 24 · 2017: 21 · 2016: 45 · 2015: 45 · 2014: 46 · 2013: 49 · 2012: 53
- FWCI
- 26.25
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of the American College of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Healthcare Systems and Public Health
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- coronary heart disease mortality, young adults, age-specific mortality, mortality trends, sex differences in mortality, cardiovascular risk factors, obesity, diabetes mellitus, blood pressure, metabolic syndrome, sentinel events
- MeSH terms
- Adult, Age Factors, Cause of Death, Coronary Disease, Female, Humans, Male, Middle Aged, Risk Factors, United States
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