Calcium-Dependent NOX5 Nicotinamide Adenine Dinucleotide Phosphate Oxidase Contributes to Vascular Oxidative Stress in Human Coronary Artery Disease

Guzik, Tomasz J., Chen, Wei, Gongora, Maria C., Guzik, Bartlomiej, Lob, Heinrich E., Mangalat, Deepa, Hoch, Nyssa, Dikalov, Sergey, Rudzinski, Pawel, Kapelak, Boguslaw, Sadowski, Jerzy, Harrison, David G.·2008·Journal of the American College of Cardiology

Cited by (280)

Items 201–280 of 280

  1. Cloning, Characteristics, and Functional Analysis of Rabbit NADPH Oxidase 5
    Feng Chen, Caiyong Yin, Christiana Dimitropoulou, David J. Fulton · 2016 · Frontiers in Physiology
  2. Targeting Reactive Oxygen Species in Atherosclerosis via Chinese Herbal Medicines
    Leyi Zhang, Jiaqin Huang, Danli Zhang, Xiaojing Lei, Yan Ma, Yun Cao, Jingling Chang · 2022 · Oxidative Medicine and Cellular Longevity
  3. Reactive Oxygen Species and the Cardiovascular System
    Augusto C. I. Montezano, Rhian M. Touyz · 2012 · Colloquium Series on Integrated Systems Physiology From Molecule to Function
  4. Exploring the protective mechanism of baicalin in treatment of atherosclerosis using endothelial cells deregulation model and network pharmacology
    Mingshuang Li, Conglin Ren · 2022 · BMC Complementary Medicine and Therapies
  5. The Molecular Regulation and Functional Roles of NOX5
    David J. Fulton · 2019 · Methods in molecular biology
  6. Impairment by Hypoxia or Hypoxia/Reoxygenation of Nitric Oxide–Mediated Relaxation in Isolated Monkey Coronary Artery: the Role of Intracellular Superoxide
    Masashi Tawa, Kohei Yamamizu, Ayman Geddawy, Takashi Shimosato, Takeshi Imamura, Kazuhide Ayajiki, Tomio Okamura · 2011 · Journal of Pharmacological Sciences
  7. Expression and Distribution of NADPH Oxidase Isoforms in Human Myometrium—Role in Angiotensin II-induced Hypertrophy1
    Xiao-Lan Cui, Baojun Chang, Leslie Myatt · 2009 · Biology of Reproduction
  8. Good Stress, Bad Stress
    Kirstin Wingler, Harald H.H.W. Schmidt · 2009 · Deutsches Ärzteblatt international
  9. Calcineurin suppresses rat H9c2 cardiomyocyteprotective autophagy under chronic intermittent hypoxia by downregulating the AMPK pathway
    Changjiang Ke, Yongjun Huang, Zhenyu Mao, Zhenghua Ke, Zeng Wang, Ruyou Li, Shenghua Long, Yuping Guo, Fei Wang, Meng Qian et al. · 2023 · Experimental Cell Research
  10. Binding of Nox5's EF-Hand domain to the peptides corresponding to the phosphorylatable region and regulatory inhibitory loop in its dehydrogenase domain
    Chin‐Chuan Wei, Evan Hay, Dustin D. Smith, Laura Lloyd, Ganesh Acharya, Rebecca Ngo · 2020 · Biophysical Chemistry
  11. Taurine Attenuates Calpain‐2 Induction and a Series of Cell Damage via Suppression of NOX‐Derived ROS in ARPE‐19 Cells
    Yuanyuan Zhang, Shu Ren, Yanting Gu, Jiahong Wang, Zheng Liu, Zhou Zhang · 2018 · Oxidative Medicine and Cellular Longevity
  12. NADP+/NADPH in Metabolism and its Relation to Cardiovascular Pathologies
    Yuanyuan Sun, Dan Wu, Qingxun Hu · 2024 · Current Medicinal Chemistry
  13. Nutritional L-Citrulline and Tetrahydrobiopterin in Peripheral Artery Disease
    Daniel Sedding, Tim M. Schmidt, Heike Bähre, Udo Bavendiek, Ana Isabel Casas, Suzi S. Chen, Vu Thao-Vi Dao, Mahmoud H. Elbatreek, Frank M. Gutzki, Andreas Hahn et al. · 2025 · JACC Advances
  14. Calmodulin binding to the dehydrogenase domain of NADPH oxidase 5 alters its oligomeric state
    Dustin D. Smith, Laura Lloyd, Elaine Wei, Paria Radmanesh, Chin‐Chuan Wei · 2022 · Biochemistry and Biophysics Reports
  15. Oxidative Stress and Hypertension
    Jing Wu, David Glenn Harrison · 2014 · Springer eBooks
  16. A novel monoclonal antibody reveals the enrichment of NADPH oxidase 5 in human splenic endothelial cells
    Zsolt Szeles, Gábor L. Petheö, Bence Szikora, Imre Kacskovıcs, Miklós Geiszt · 2023 · Scientific Reports
  17. Extracellular Redox Balance as a Determinant of Immune Regulation and Tissue Inflammation
    Rebecca Seitz, Martina A. Müller, Karsten Gülow · 2026 · Antioxidants
  18. Identification of an inhibitor for atherosclerotic enzyme NOX-1 to inhibit ROS production
    Rik Ganguly, Angneh Ngoruh, Prosperwell Ingty, Shashi Kumar Yadav, Atanu Bhattacharjee · 2023 · Future Journal of Pharmaceutical Sciences
  19. Angiotensin II and Superoxide Generation
    Sergey Dikalov, David Glenn Harrison · 2014 · Springer eBooks
  20. Diagnosis and individual treatment of cardiovascular diseases: targeting vascular oxidative stress
    Melanie E. Armitage, Mylinh La, Harald H.H.W. Schmidt, Kirstin Wingler · 2010 · Expert Review of Clinical Pharmacology
  21. The Role of NADPH Oxidases in Cardiovascular Disease
    Wen Zhang · 2016 · Journal of Vascular Medicine & Surgery
  22. Metal binding and conformational studies of the calcium binding domain of NADPH oxidase 5 reveal its similarity and difference to calmodulin
    Chin‐Chuan Wei, Emily Fabry, Evan Hay, Laura Lloyd, Nichole E. M. Kaufman, Yaping Yang, Dennis J. Stuehr · 2019 · Journal of Biomolecular Structure and Dynamics
  23. Oxidative stress in carotid arteries of patients submitted to carotid endarterectomy. The role of aging process
    Márcio Luı́s Lucas, Cristina Campos Carraro, Adriane Belló‐Klein, Antônio Nocchi Kalil, Newton Roech Aerts · 2016 · Acta Cirúrgica Brasileira
  24. Vascular NADPH Oxidases and Atherothrombotic Stroke
    Javier Marqués, Guillermo Zalba · 2024 · Stresses
  25. Oxidative Stress in Cardiovascular Diseases: Mechanisms and Exploring Advanced Therapies
    Dushyant, Balram Balram, Gurvirender Singh, Nitish Kumar, Smita Narwal, Ashwani K. Dhingra · 2025 · Cardiovascular & Hematological Agents in Medicinal Chemistry
  26. Isoform-Selective Nox Inhibitors: Advances and Future Perspectives
    Christopher M. Dustin, Eugenia Cifuentes-Pagano, Patrick J. Pagano · 2023 · Springer eBooks
  27. Delineating the NOX-Mediated Promising Therapeutic Strategies for the Management of Various Cardiovascular Disorders: A Comprehensive Review
    Rohit Kumar Upadhyay, Kuldeep Kumar, Vishal Kumar Vishwakarma, Nirmal Singh, Rajiv Narang, Neeraj Parakh, Mayank Yadav, Sangeeta Yadav, Sachin Kumar, Ahsas Goyal et al. · 2024 · Current Vascular Pharmacology
  28. NAD(P)H oxidase isoforms as therapeutic targets for diabetic complications
    Stephen P. Gray, Jay C. Jha, Elyse Di Marco, Karin Agnes Maria Jandeleit-Dahm · 2014 · Expert Review of Endocrinology & Metabolism
  29. Role of Oxidative Stress in Hypertension
    Sophocles Chrissobolis, Quynh Nhu Dinh, Grant Raymond Drummond, Christopher Graeme Sobey · 2016 · Oxidative stress in applied basic research and clinical practice
  30. Relationship Between Carbohydrate Antigen 125 and Coronary Artery Calcification in Patients without Known Coronary Artery Disease
    Kun Fu, Huadong Liu, KuerBanJiang MaMuTi, Dongnan Hu, Peng Hao · 2018 · Medical Science Monitor
  31. Reactive oxygen species, oxidative stress, and cardiovascular diseases
    Fatemeh Sharifpanah, Heinrich Sauer · 2016 · Wiley eBooks
  32. Isoform-selective NADPH oxidase inhibitor panel for pharmacological target validation
    Vu Thao-Vi Dao, Mahmoud H. Elbatreek, Sebastian Altenhöfer, Ana Isabel Casas, Mayra Pacheco Pachado, Christopher T. Neullens, U. Knaus, Harald H.H.W. Schmidt · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  33. NADPH oxidase 5: Where are we now and which way to proceed?
    Gábor L. Petheö, Zsolt Szeles, Miklós Geiszt · 2024 · Redox Biochemistry and Chemistry
  34. Functional Implications of Reactive Oxygen Species (ROS) in Human Blood Vessels
    Tomasz Jan Guzik, Agata Schramm‐Luc, Marta Cześnikiewicz‐Guzik · 2014 · Springer eBooks
  35. NADPH Oxidases: Structure and Function
    Mark T. Quinn · 2013 · Wiley eBooks
  36. NADPH Oxidase 5 (NOX5) Upregulates MMP-10 Production and Cell Migration in Human Endothelial Cells
    Javier Marqués, Elena Ainzúa, Josune Orbe, María Martínez-Azcona, José Martínez‐González, Guillermo Zalba · 2024 · Antioxidants
  37. Oxidase Interactions in Cardiovascular Disease
    Ji Youn Youn, Kin Lung Siu, Qiang Li, David Glenn Harrison, Hua “Linda” Cai · 2014 · Springer eBooks
  38. Reactive Oxygen Species, Oxidative Stress, and Hypertension
    Rhian M. Touyz, Andréia Z. Chignalia, Mona H. Sedeek · 2010 · Humana Press eBooks
  39. From ST segments to endothelial pathophysiology: hypercholesterolemia and endothelial superoxide production
    David Glenn Harrison · 2014 · Journal of Clinical Investigation
  40. To activate NAD (P)H oxidase with a brief pulse of photodynamic action
    Xiao Bing Xie, Yu Shu, Zong Jie Cui · 2024 · The FASEB Journal
  41. Role of Oxidative Stress and Targeted Antioxidant Therapies in Experimental Models of Diabetic Complications
    Judy B. de Haan, Karin Agnes Maria Jandeleit-Dahm, Terri J. Allen · 2011 · Humana Press eBooks
  42. Vascular Biology of Reactive Oxygen Species and NADPH Oxidases: Role in Atherogenesis
    Adrian Manea · 2012 · InTech eBooks
  43. Lessons from Experimental-Induced Atherosclerosis: Valuable for the Precision Medicine of Tomorrow
    Manuela Călin, Elena Dragomir Butoi, Simona‐Adriana Manea, Maya Simionescu, Adrian Manea · 2016 · Springer eBooks
  44. Roles of Hydrogen Peroxide in the Regulation of Vascular Tone
    Christopher P. Stanley, Ghassan J. Maghzal, Roland Stocker · 2017 · CRC Press eBooks
  45. Oxidant-Dependent and Oxidant-Independent Proangiogenic and Vasomotor Signaling in Coronary Vascular Endothelium
    Sarah Aldosari, Maan A. Awad, May Z. Gao, Isabella G. McCormack, Frank William Sellke, Md. Ruhul Abid · 2019 · Springer eBooks
  46. Knock, Knock: Who’s There?
    Hana A. Itani, Sergey Dikalov, David Glenn Harrison · 2013 · Circulation
  47. Pathogenesis of Macrovascular Complications in Diabetes
    Stephen P. Gray, Elyse Di Marco, Riccardo Candido, Mark Emmanuel Cooper, Karin Agnes Maria Jandeleit-Dahm · 2016 · Wiley eBooks
  48. Oxidative Stress and Antioxidant Strategies in Human Diseases
    Kefei Yuan, Yuanyuan Zhang · 2021 · Springer eBooks
  49. Highlights of the Year in JACC 2008
    Anthony Nicholas DeMaria, Ori Ben‐Yehuda, Jeroen Joost Bax, Gregory K. Feld, Barry Greenberg, Wilbur Y.W. Lew, João A.C. Lima, Alan S. Maisel, Sanjiv M. Narayan, David J. Sahn et al. · 2009 · Journal of the American College of Cardiology
  50. Oxidoreductase
    Mahmoud Ahmed Mansour · 2020 · IntechOpen eBooks
  51. A New Biomarker in The Distinction Between Stable Coronary Artery Disease and Acute Coronary Syndrome:Thiols
    Gökhan Ergün, Şaban Keleşoğlu, K Tekin, Bekir Çalapkorur, Fatih Balcı, Özcan Erel, Salim Neşeli̇oğlu, Deniz Elçik · 2022 · Journal of Contemporary Medicine
  52. Nox5: Molecular Regulation and Pathophysiology
    Lívia L. Camargo, Francisco J. O. Rios, Augusto C. I. Montezano, Rhian M. Touyz · 2023 · Springer eBooks
  53. Reactive Oxygen Species, Vascular Disease, and Hypertension
    Augusto C. I. Montezano, Rhian M. Touyz · 2014 · Springer eBooks
  54. Vascular pathophysiology of hypertension
    Tomasz Jan Guzik, Rhian M. Touyz · 2017 · Oxford University Press eBooks
  55. NADPH Oxidase and Atherosclerosis
    Jamie Y. Jeremy, Saima Muzaffar, Carina Mill, Nilima Shukla · 2010 · Atherosclerosis
  56. Pathogenesis of Macrovascular Complications in Diabetes
    Jakob Appel Østergaard, Tomasz J. Block, Sophia I. Dahm, Waheed Khan, Karin Agnes Maria Jandeleit-Dahm · 2024 · Wiley eBooks
  57. Functional Studies of NADPH Oxidases in Human Vasculature
    Tomasz Jan Guzik · 2010 · Humana Press eBooks
  58. Evaluation of pharmacological properties of Danshen compounds by computational and biochemical approaches
    Zhou, Zhiwei · 2016 · RMIT Research Repository (RMIT University Library)
  59. Estudio del nivel de estrés oxidativo y valoración de la expresión de genes relacionados en la Aterosclerosis Carotidea
    Nuria Zamora-González · 2015
  60. Metalloproteinases, Sialidases and NADPH Oxidases as Key Enzymes involved in Atherosclerosis Development
    Anastasia Vladimirovna Poznyak, Dmitry Alexandrovich Kashirskikh, Victoria Alexandrovna Khotina, Andrey V. Grechko, Alexander Nikolaevich Orekhov · 2019 · Archives of Clinical Microbiology
  61. Oral anticoagulants as double-edged swords
    van Gorp Rick Henricus Petrus · 2020 · Research Publications (Maastricht University)
  62. Role of Subcellular ROS in Providing Resilience to Vascular Endothelium
    Sarah Aldosari, Maan A. Awad, Frank William Sellke, Md. Ruhul Abid · 2020 · IntechOpen eBooks
  63. Role of vascular remodeling in atherosclerosis and aortic aneurysm
    Petsohonsakul Ploingarm · 2020
  64. p22phox y NADPH oxidasas en la hematopoyesis in vivo
    Rodrigo Bermejo · 2020 · Gredos (University of Salamanca)
  65. FAIR and bias-free network modules for mechanism-based disease redefinitions
    Ahmed Hassan · 2021 · Research Publications (Maastricht University)
  66. c-Src regulatory role of NOX5 activation and hypertension: a new piece of the puzzle
    Stephanie M. Cicalese, Satoru Eguchi · 2021 · Cardiovascular Research
  67. Biological activity of anthocyanins and their phenolic degradation products and metabolites in human vascular endothelial cells
    Michael Edwards · 2013 · UEA Digital Repository (University of East Anglia)
  68. Erratum
    2012 · Annals of Medicine
  69. Vascular Reactive Oxygen Species Biology – Insights from Transgenic and Knockout Mouse Models
    Sih Min Tan, Judy B. de Haan · 2014 · Springer eBooks
  70. Exploring the protective mechanism of baicalin in treatment of atherosclerosis using endothelial cells degranulation model and network pharmacology
    Conglin Ren, Mingshuang Li · 2022 · Research Square
  71. A study of the contaminant mixture of lead, cadmium and methylmercury for their effects on endothelial function under conditions typifying specific diets and lifestyles for northern populations
    Saad Ulhaq · 2013
  72. NADPH oxidase 5 is a novel gene for type 2 diabetes susceptibility determined by gene-body mass index and gene-environment interactions
    Iuliia E. Azarova, Elena Yu. Klyosova, Valentina Azarova, Alexey Polonikov · 2023 · Research Square
  73. Molecular mechanisms of reactive oxygen species and regulation of gene expression in cardiometabolic syndrome
    Martyna Fronczek, Maciej Banach, Marcin Goławski, Tadeusz Osadnik · 2025 · Elsevier eBooks
  74. NADPH oxidase, obesity, and metabolic syndrome: Therapeutic opportunity
    Irina V. Tikhonova, Valentina G. Safronova · 2025 · Elsevier eBooks
  75. Nε-(carboxymethyl)lysine-modified albumin exacerbates doxorubicin-induced NOX5-dependent oxidative stress in endothelial cells
    Zhu Jiang, Ingeborg S. E. Waas, Suat Şimşek, Casper G. Schalkwijk, Joris J. T. H. Roelofs, Hans W.M. Niessen, Paul A.J. Krijnen · 2025 · Biochemical and Biophysical Research Communications
  76. Additional file 1 of Identification of an inhibitor for atherosclerotic enzyme NOX-1 to inhibit ROS production
    Rik Ganguly, Angneh Ngoruh, Prosperwell Ingty, Shashi Kumar Yadav, Bhattacharjee, Atanu · 2023 · Figshare
  77. The changing epidemiology of human type 2 diabetes–associated atherosclerosis: Pathophysiological mechanisms and emerging treatment possibilities
    Dania Al-Sharify, Jiangming Sun, Andreas Edsfeldt · 2026 · Journal of Internal Medicine
  78. Renalase and Total Antioxidant Status in Relation to CCTA-Assessed Coronary Artery Disease Severity in Suspected Obstructive Sleep Apnea
    Paweł Gać, Michał Fułek, Monika Michałek-Zrąbkowska, Piotr Macek, Małgorzata Poręba, Helena Martynowicz, Rafał Poręba · 2026 · Antioxidants
  79. NADPH oxidases in immunometabolism and disease pathology: mechanistic networks, pollutant triggers, and therapeutic frontiers
    M. Thakur, D Mutyala, AA Amoliga, M. Contin Ortega, S. Batra · 2026 · Cellular and Molecular Immunology
  80. The Reactive Carbonyl Methylglyoxal Suppresses Vascular KATP Channels by MRNA Destabilization
    Anuhya S. Konduru · 2022 · Digital Archive @ GSU