Harrison, David G.

Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress

Cai, H., & Harrison, D. G. (2000) · Circulation Research

Nitric Oxide and Endothelin EffectsCardiovascular Health and Disease Prevention

Cited by 3,839

Hypercholesterolemia increases endothelial superoxide anion production.

Ohara, Y., Peterson, T. E., & Harrison, D. G. (1993) · Journal of Clinical Investigation

Nitric Oxide and Endothelin EffectsNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 1,765

Role of the T cell in the genesis of angiotensin II–induced hypertension and vascular dysfunction

Guzik, T. J., Hoch, N. E., Brown, K. A., McCann, L. A., Rahman, A., Dikalov, S., Goronzy, J., Weyand, C., & Harrison, D. G. (2007) · The Journal of Experimental Medicine

Renin-Angiotensin System StudiesAtherosclerosis and Cardiovascular Diseases

Cited by 1,736

Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension

Landmesser, U., Dikalov, S., Price, S. R., McCann, L., Fukai, T., Holland, S. M., Mitch, W. E., & Harrison, D. G. (2003) · Journal of Clinical Investigation

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 1,660

Role of oxidative stress in atherosclerosis

Harrison, D., Griendling, K. K., Landmesser, U., Hornig, B., & Drexler, H. (2003) · The American Journal of Cardiology

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 1,275

Endothelial Regulation of Vasomotion in ApoE-Deficient Mice: Implications for Interactions Between Peroxynitrite and Tetrahydrobiopterin

Laursen, J. B., Somers, M., Kurz, S., McCann, L., Warnholtz, A., Freeman, B. A., Tarpey, M., Fukai, T., & Harrison, D. G. (2001) · Circulation

Nitric Oxide and Endothelin EffectsCardiovascular Health and Disease Prevention

Cited by 721

Molecular Mechanisms of Angiotensin II–Mediated Mitochondrial Dysfunction: Linking Mitochondrial Oxidative Damage and Vascular Endothelial Dysfunction

Doughan, A. K., Harrison, D. G., & Dikalov, S. I. (2008) · Circulation Research

Nitric Oxide and Endothelin EffectsMitochondrial Function and Pathology

Cited by 710

Inflammation, Immunity, and Hypertensive End-Organ Damage

McMaster, W. G., Kirabo, A., Madhur, M. S., & Harrison, D. G. (2015) · Circulation Research

Renin-Angiotensin System StudiesAtherosclerosis and Cardiovascular Diseases

Cited by 708

Interactions of Peroxynitrite, Tetrahydrobiopterin, Ascorbic Acid, and Thiols

Kuzkaya, N., Weissmann, N., Harrison, D. G., & Dikalov, S. (2003) · Journal of Biological Chemistry

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 692

The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases

Cai, H., Griendling, K. K., & Harrison, D. G. (2003) · Trends in Pharmacological Sciences

Nitric Oxide and Endothelin EffectsNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 687

p22phox mRNA Expression and NADPH Oxidase Activity Are Increased in Aortas From Hypertensive Rats

Fukui, T., Ishizaka, N., Rajagopalan, S., Laursen, J. B., Capers, Q., Taylor, W. R., Harrison, D. G., de Leon, H., Wilcox, J. N., & Griendling, K. K. (1997) · Circulation Research

Nitric Oxide and Endothelin EffectsRenin-Angiotensin System Studies

Cited by 553

Measurement of Reactive Oxygen Species in Cardiovascular Studies

Dikalov, S., Griendling, K. K., & Harrison, D. G. (2007) · Hypertension

Nitric Oxide and Endothelin EffectsAntioxidant Activity and Oxidative Stress

Cited by 532

Inflammatory Markers and Incident Heart Failure Risk in Older Adults

Kalogeropoulos, A., Georgiopoulou, V., Psaty, B. M., Rodondi, N., Smith, A. L., Harrison, D. G., Liu, Y., Hoffmann, U., Bauer, D. C., Newman, A. B., et al. (2010) · Journal of the American College of Cardiology

Heart Failure Treatment and ManagementCardiac Fibrosis and Remodeling

Cited by 478

Transcriptional and Posttranscriptional Regulation of Endothelial Nitric Oxide Synthase Expression by Hydrogen Peroxide

Drummond, G. R., Cai, H., Davis, M. E., Ramasamy, S., & Harrison, D. G. (2000) · Circulation Research

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 430

Calcium-Dependent NOX5 Nicotinamide Adenine Dinucleotide Phosphate Oxidase Contributes to Vascular Oxidative Stress in Human Coronary Artery Disease

Guzik, T. J., Chen, W., Gongora, M. C., Guzik, B., Lob, H. E., Mangalat, D., Hoch, N., Dikalov, S., Rudzinski, P., Kapelak, B., et al. (2008) · Journal of the American College of Cardiology

Nitric Oxide and Endothelin EffectsNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 281

Coronary Artery Superoxide Production and Nox Isoform Expression in Human Coronary Artery Disease

Guzik, T. J., Sadowski, J., Guzik, B., Jopek, A., Kapelak, B., Przybyłowski, P., Wierzbicki, K., Korbut, R., Harrison, D. G., & Channon, K. M. (2006) · Arteriosclerosis, Thrombosis, and Vascular Biology

Nitric Oxide and Endothelin EffectsNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 278

Requirement of argininosuccinate lyase for systemic nitric oxide production

Erez, A., Nagamani, S. C. S., Shchelochkov, O. A., Premkumar, M. H., Campeau, P. M., Chen, Y., Garg, H. K., Li, L., Mian, A., Bertin, T. K., et al. (2011) · Nature Medicine

Nitric Oxide and Endothelin EffectsAmino Acid Enzymes and Metabolism

Cited by 233

Renal Denervation Prevents Immune Cell Activation and Renal Inflammation in Angiotensin II–Induced Hypertension

Xiao, L., Kirabo, A., Wu, J., Saleh, M. A., Zhu, L., Wang, F., Takahashi, T., Loperena, R., Foss, J. D., Mernaugh, R. L., et al. (2015) · Circulation Research

Renin-Angiotensin System StudiesBlood Pressure and Hypertension Studies

Cited by 233

Role of Extracellular Superoxide Dismutase in Hypertension

Gongora, M. C., Qin, Z., Laude, K., Kim, H. W., McCann, L., Folz, J. R., Dikalov, S., Fukai, T., & Harrison, D. G. (2006) · Hypertension

Nitric Oxide and Endothelin EffectsRenin-Angiotensin System Studies

Cited by 204

Validation of lucigenin as a chemiluminescent probe to monitor vascular superoxide as well as basal vascular nitric oxide production

Skatchkov, M. P., Sperling, D., Hink, U., Mülsch, A., Harrison, D. G., Sindermann, I., Meinertz, T., & Münzel, T. (1999) · Biochemical and Biophysical Research Communications

Nitric Oxide and Endothelin EffectsNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 188

Upregulation of nox1 in vascular smooth muscle leads to impaired endothelium-dependent relaxation via enos uncoupling

Dikalova, A. E., Góngora, M. C., Harrison, D. G., Lambeth, J. D., Dikalov, S., & Griendling, K. K. (2010) · American Journal of Physiology-Heart and Circulatory Physiology

Nitric Oxide and Endothelin EffectsEicosanoids and Hypertension Pharmacology

Cited by 179

Tyrosine metabolism during interferon-alpha administration: Association with fatigue and CSF dopamine concentrations

Felger, J. C., Li, L., Marvar, P. J., Woolwine, B. J., Harrison, D. G., Raison, C. L., & Miller, A. H. (2013) · Brain, Behavior, and Immunity

Tryptophan and brain disordersAmino Acid Enzymes and Metabolism

Cited by 176

Physiologic consequences of increased vascular oxidant stresses in hypercholesterolemia and atherosclerosis: Implications for impaired vasomotion

Harrison, D. G., & Ohara, Y. (1995) · The American Journal of Cardiology

Nitric Oxide and Endothelin EffectsCardiovascular Health and Disease Prevention

Cited by 163

Induction of Endothelial NO Synthase by Hydrogen Peroxide via a Ca 2+ /Calmodulin-Dependent Protein Kinase II/Janus Kinase 2–Dependent Pathway

Cai, H., Davis, M. E., Drummond, G. R., & Harrison, D. G. (2001) · Arteriosclerosis, Thrombosis, and Vascular Biology

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 160