Cited by 535Cardiac Health and Mental HealthTreatment of Major DepressionHeart Failure Treatment and Management

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Safety and Efficacy of Sertraline for Depression in Patients With Heart Failure

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O'Connor, Christopher M., Jiang, Wei, Kuchibhatla, Maragatha, Silva, Susan G., Cuffe, Michael S., Callwood, Dwayne D., Zakhary, Bosh, Stough, Wendy Gattis, Arias, Rebekka M., Rivelli, Sarah K., Krishnan, Ranga·2010·Journal of the American College of Cardiology

DOI 10.1016/j.jacc.2010.03.068PMC PMC3663330

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Abstract

Objectives The objective was to test the hypothesis that heart failure (HF) patients treated with sertraline will have lower depression scores and fewer cardiovascular events compared with placebo.Background Depression is common among HF patients. It is associated with increased hospitalization and mortality.Methods The SADHART-CHF (Sertraline Against Depression and Heart Disease in Chronic Heart Failure) trial was a randomized, double-blind, placebo-controlled trial of sertraline 50 to 200 mg/day versus matching placebo for 12 weeks. All participants also received nurse-facilitated support. Eligible patients were age 45 years or older with HF (left ventricular ejection fraction < or =45%, New York Heart Association functional class II to IV) and clinical depression (Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition criteria for current major depressive disorder). Those with significant cognitive impairment, psychosis, recent alcohol or drug dependence, bipolar or severe personality disorder, active suicidal ideation, and current antipsychotic or antidepressant medications were excluded. Primary end points were change in depression severity (Hamilton Depression Rating Scale total score) and composite cardiovascular status at 12 weeks.Results A total of 469 patients were randomized (n = 234 sertraline, n = 235 placebo). The mean +/- SE change from baseline to 12 weeks in the Hamilton Depression Rating Scale total score was -7.1 +/- 0.5 (sertraline) and -6.8 +/- 0.5 (placebo) (p < 0.001 from baseline, p = 0.89 between groups, mean change between groups -0.4; 95% confidence interval: -1.7 to 0.92). The proportions whose composite cardiovascular score worsened, improved, or was unchanged were 29.9%, 40.6%, and 29.5%, respectively, in the sertraline group and 31.1%, 43.8%, and 25.1%, respectively, in the placebo group (p = 0.78).Conclusions Sertraline was safe in patients with significant HF. However, treatment with sertraline compared with placebo did not provide greater reduction in depression or improved cardiovascular status among patients with HF and depression. (Antidepressant Medication Treatment for Depression in Individuals With Chronic Heart Failure [SADHART-CHF]; NCT00078286).

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ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult
Hunt, S. A. (2005) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2005.08.022 · Cited by 4,135
Heart Disease and Stroke Statistics—2009 Update
WRITING GROUP MEMBERS, Lloyd‐Jones, D. M., Adams, R. J., Carnethon, M. R., SIMONE, G. D., Ferguson, T. B., Flegal, K. M., Ford, E. S., Furie, K. L., Go, A. S., et al. (2009) · Circulation · doi:10.1161/circulationaha.108.191259 · Cited by 3,914
ESC Guidelines for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2008
Dickstein, K., Authors Task Force Members, Solal, A. C., Filippatos, G. S., McMurray, J. J. V., Ponikowski, P. P., Poole-Wilson, P. A., Strömberg, A., van Veldhuisen, D. J., Atar, D., et al. (2008) · European Journal of Heart Failure · doi:10.1016/j.ejheart.2008.08.005 · Cited by 3,532
Heart Disease and Stroke Statistics—2009 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
WRITING GROUP MEMBERS, Lloyd-Jones, D., Adams, R., Carnethon, M., De Simone, G., Ferguson, T. B., Flegal, K., Ford, E., Furie, K., Go, A., et al. (2009) · Circulation · doi:10.1161/circulationaha.108.191261 · Cited by 3,140
ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association of the ESC (HFA) and endorsed by the European Society of Intensive Care Medicine (ESICM)
Authors Task Force Members, Dickstein, K., Solal, A. C., Filippatos, G., McMurray, J. J. V., Ponikowski, P. P., Poole-Wilson, P. A., Strömberg, A., van Veldhuisen, D. J., Atar, D., et al. (2008) · European Heart Journal · doi:10.1093/eurheartj/ehn309 · Cited by 2,705
ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure): Developed in Collaboration With the American College of Chest Physicians and the International Society for Heart and Lung Transplantation: Endorsed by the Heart Rhythm Society
WRITING COMMITTEE MEMBERS, Hunt, S. A., Abraham, W. T., Chin, M. H., Feldman, A. M., Francis, G. S., Ganiats, T. G., Jessup, M., Konstam, M. A., Mancini, D. M., et al. (2005) · Circulation · doi:10.1161/circulationaha.105.167586 · Cited by 2,251
The Seattle Heart Failure Model
Levy, W. C., Mozaffarian, D., Linker, D. T., Sutradhar, S., Anker, S. D., Cropp, A. B., Anand, I. S., Maggioni, A. P., Burton, P. B. J., Sullivan, M. D., et al. (2006) · Circulation · doi:10.1161/circulationaha.105.584102 · Cited by 2,024
Antidepressant Drug Effects and Depression Severity: A Patient-Level Meta-analysis
Fournier, J. C., DeRubeis, R. J., Hollon, S. D., Dimidjian, S., Amsterdam, J. D., Shelton, R. C., & Fawcett, J. (2010) · JAMA · doi:10.1001/jama.2009.1943 · Cited by 2,009
Effects of candesartan on mortality and morbidity in patients with chronic heart failure: the CHARM-Overall programme
Pfeffer, M. A., Swedberg, K. B., Granger, C. B., Held, P., McMurray, J. J. V., Michelson, E. L., Olofsson, B., Östergren, J., & Yusuf, S. (2003) · The Lancet · doi:10.1016/s0140-6736(03)14282-1 · Cited by 1,893
Depression in heart failure
Rutledge, T., Reis, V. A., Linke, S. E., Greenberg, B. H., & Mills, P. J. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.06.055 · Cited by 1,513

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Nair, 1999, Depression, coronary events, platelet inhibition, and serotonin reuptake inhibitors, Am J Cardiol, 84, 321

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Psychosomatik der Herzinsuffizienz
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Anjum, S., & Bathla, M. (2020) · Indian Journal of Pharmacology · doi:10.4103/ijp.ijp_618_18 · Cited by 11
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Kewcharoen, J., Tachorueangwiwat, C., Kanitsoraphan, C., Saowapa, S., Nitinai, N., Vutthikraivit, W., Rattanawong, P., & Banerjee, D. (2021) · Minerva Cardiology and Angiology · doi:10.23736/s2724-5683.20.05346-3 · Cited by 10
Geriatric Domains in Patients with Heart Failure with Preserved Ejection Fraction
Goyal, P., Zainul, O., Marshall, D., & Kitzman, D. W. (2022) · Cardiology Clinics · doi:10.1016/j.ccl.2022.06.006 · Cited by 10

Authors: O'Connor, C. M., Jiang, W., Kuchibhatla, M., Silva, S. G., Cuffe, M. S., Callwood, D. D., Zakhary, B., Stough, W. G., Arias, R. M., Rivelli, S. K., & Krishnan, R.
Affiliations: Duke Medical Center (US)
Duke University (US)
University of North Carolina at Chapel Hill (US)
Virginia Research Institute (US)
Campbell University (US)
ORCID: Jiang, Wei
Kuchibhatla, Maragatha
Silva, Susan G.
Stough, Wendy Gattis
Arias, Rebekka M.
Krishnan, Ranga
Venue: Journal of the American College of Cardiology
Publisher: Elsevier BV
Published: 2010-08
Volume: 56
Issue: 9
Pages: 692-699
ISSN: 0735-1097 (ISSN-L)
DOI: 10.1016/j.jacc.2010.03.068
PMC: PMC3663330
OpenAlex: W1608367062
Cited by: 535
References: 36
Citations by year: 2026: 29 · 2025: 23 · 2024: 21 · 2023: 28 · 2022: 35 · 2021: 27 · 2020: 40 · 2019: 49 · 2018: 35 · 2017: 39 · 2016: 42 · 2015: 36 · 2014: 23 · 2013: 38 · 2012: 37
FWCI: 23.49
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 1080 d)
Locations: Journal of the American College of Cardiology (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute of Mental Health
Pfizer, Inc.
NIMH
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
Keywords: sertraline, heart failure, depression, major depressive disorder, antidepressants, cardiovascular events, drug safety, depression severity
MeSH terms: Aged, Antidepressive Agents, Chronic Disease, Depression, Female, Heart Failure, Humans, Male, Middle Aged, Sertraline

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Safety and Efficacy of Sertraline for Depression in Patients With Heart Failure

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