Triggering of Symptomatic Atrial Fibrillation by Negative Emotion
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Acute instances of distress can lead to immediate changes and even dramatic elevations in catecholamines.
“Acute instances of distress can lead to immediate changes and even dramatic elevations in catecholamines. 102-107”
From Psychological Health, Well-Being, and the Mind-Heart-Body Connection: A Scientific Statement From the American Heart Association (2021) · cites this paper as [103]
The Results passages report that stress and other negative emotions preceded symptomatic atrial fibrillation, not that distress changed catecholamine levels. A search of the indexed paper for catecholamines and related sympathetic-response terms found no passage addressing immediate or dramatic catecholamine elevations (page numbers unavailable). (LLM, conf=0.75)
Experimental — accuracy not yet measuredAnxiety and psychological stress are highly prevalent among people with AF, affecting 25% to 45% of patients, and are associated with greater symptom burden, higher rates of health care utilization, and worse quality of life.
“Anxiety and psychological stress are also highly prevalent among people with AF, affecting 25% to 45% of patients, 11 , 12 , 13 and are associated with greater symptom burden, higher rates of health care utilization, and worse quality of life.”
From Wearable Devices, Health Care Use, and Psychological Well-Being in Patients With Atrial Fibrillation (2024) · cites this paper as [11]
The citation is attached to the estimate that anxiety and stress affect 25% to 45% of patients with AF. The paper’s Results report that anxiety and stress preceded symptomatic AF episodes, but do not give a prevalence estimate among patients with AF; searches for the percentage and prevalence found none. (LLM, conf=0.76)
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“Previous studies suggested that negative emotion including sadness, depression, anger and stress could increase the likelihood of symptomatic AF (Lampert et al., 2014).”
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“To date, only one study (25) has investigated negative emotions as a trigger of episodes of AF in a crossover study design.”
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“Additional studies have implicated roles for stress, anxiety, sadness, and post-traumatic stress disorder as examples of emotional distress that increase the initiation, propagation, and recurrence of AF [26, 31–35].”
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“Similarly, negative emotions (e.g., anger, anxiety) can trigger cardiovascular events (e.g., ventricular arrhythmias, myocardial infarction, atrial fibrillation; Lampert et al. 2002, 2014; Mittleman et al. 1995).”
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“Previous studies have systematically and prospectively revealed that negative emotions such as stress, sadness, anger, and anxiety can induce AF, while happiness has a protective effect on AF (28).”
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Large Language Modeling–Enabled Analysis of Atrial Fibrillation on Social Media
Parsa, S., Somani, S. S., Rogers, A. J., Hernandez‐Boussard, T., Jain, S. S., & Rodríguez, F. (2025) · Journal of the American Heart Association · doi:10.1161/jaha.125.043999 · Cited by 1 · see citing works
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“Integrating life course epidemiologic models and causal mediation analysis may offer insights into disease pathways and provide opportunities for early intervention.”
A New Predisposing Factor for Postoperative Atrial Fibrillation: Tube Insertion Site
Apaydın, Z., Timur, B., Yazıcı, B., Karakoç, K. G., Akbaş, A., Aksu, T., & İyigün, T. (2024) · The Thoracic and Cardiovascular Surgeon · doi:10.1055/a-2474-2827 · Cited by 1 · see citing works
Emotions & Heart:Exploring the Impact of Negative Emotions on Cardiovascular Health
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Weitere wichtige Krankheitsbilder und Interventionen in der Kardiologie
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Psychosomatische Aspekte bei Vorhofflimmern
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Exposure-based cognitive behavior therapy for atrial fibrillation : a novel treatment paradigm
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Other Important Clinical Pictures and Interventions in Cardiology
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“Negative emotions have been shown in studies to be risk factors for the recurrence of atrial fibrillation and to be extremely detrimen - tal to patients' postoperative recovery [26].”
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Glyphosate poisoning causing atrial fibrillation: Rarely seen, rarely heard
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“This aligns with research suggesting that personalization and contextualization of health goals can motivate lifestyle changes (Antonoplis & Chen, 2021; Arnold et al., 2012; Kim et al., 2019; Lampert et al., 2014; Schaefer et al., 2013).”
Elamir, A. A. K. M., Adam, Y. A. M., Abdel-Rahman, I. M., Elnosh, H. A. A., Mohammad, M. A. A., Ahmed, O., Ahmed, R. A. O., Ahmed, A. A., Ahmed, R. A. A., & Farah, A. F. A. (2026) · Sport Sciences for Health · doi:10.1007/s11332-025-01641-1
“Depression and anxiety usually co-exist in AF, contributing to increased psychological stress and decreased quality of life, which might also exacerbate autonomic dysregulation and increase AF episodes [9, 31, 32].”
Influential
- Authors
- Lampert, R., Jamner, L., Burg, M., Dziura, J., Brandt, C., Liu, H., Li, F., Donovan, T., & Soufer, R.
- Affiliations
- Yale University (US)
- Corresponding author
- Lampert, Rachel
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 2014-10
- Volume
- 64
- Issue
- 14
- Pages
- 1533-1534
- ISSN
- 0735-1097 (ISSN-L)
- OpenAlex
- W1994562580
- Cited by
- 90
- References
- 5
- Citations by year
- 2026: 3 · 2025: 11 · 2024: 9 · 2023: 6 · 2022: 19 · 2021: 7 · 2020: 6 · 2019: 10 · 2018: 7 · 2017: 7 · 2016: 2 · 2015: 3
- FWCI
- 2.75
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of the American College of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- U.S. Public Health Service
- National Heart, Lung, and Blood Institute (R01HL073285)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Keywords
- atrial fibrillation, negative emotions, emotional stress, autonomic nervous system, ventricular arrhythmias, myocardial infarction
- MeSH terms
- Anger, Anxiety, Atrial Fibrillation, Emotions, Humans, Prospective Studies, Stress, Psychological, Electrocardiography, Ambulatory, Self Report
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