Pregnancy complications in women with heart disease conceiving with fertility therapy
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Fertility therapy may confer unintended health risks to women.
“Although fertility therapy represents a safe and feasible option for many couples with infertility, these treatments may confer unintended health risks to women.”
From Cardiovascular Risk Following Fertility Therapy (2017) · cites this paper as [18]
Recent observational data indicate double the risk of severe maternal morbidity in fertility-treated pregnancy when compared with naturally conceived pregnancy.
“For example, recent observational data indicate double the risk of severe maternal morbidity (13,18,19) in fertility-treated pregnancy when compared with naturally conceived pregnancy.”
From Cardiovascular Risk Following Fertility Therapy (2017) · cites this paper as [18]
Fertility therapy is widely used to achieve pregnancy among older women.
“This question is increasingly relevant because fertility therapy is widely used to achieve pregnancy among older women, is associated with short-term maternal complications (13,18,19), and its long-term CV safety is unknown.”
From Cardiovascular Risk Following Fertility Therapy (2017) · cites this paper as [18]
Fertility therapy is associated with short-term maternal complications.
“This question is increasingly relevant because fertility therapy is widely used to achieve pregnancy among older women, is associated with short-term maternal complications (13,18,19), and its long-term CV safety is unknown.”
From Cardiovascular Risk Following Fertility Therapy (2017) · cites this paper as [18]
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Cites
Prospective Multicenter Study of Pregnancy Outcomes in Women With Heart Disease
Siu, S. C., Sermer, M., Colman, J. M., Alvarez, A. N., Mercier, L., Morton, B. C., Kells, C. M., Bergin, M. L., Kiess, M. C., Marcotte, F., et al. (2001) · Circulation · doi:10.1161/hc3001.093437 · Cited by 1,401 · see citing works
Self-citationPredictors of pregnancy complications in women with congenital heart disease
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RETIRED: Pregnancy Outcomes After Assisted Reproductive Technology
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Long term cardiovascular risk in women prescribed fertility therapy
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Self-citationPregnancy in women with congenital heart disease
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Pregnancy in women with congenital heart disease.
Greutmann, M., & Pieper, P. (2015) · European Heart Journal · doi:10.1093/eurheartj/ehv288 · Cited by 57 · see citing works
Cardiovascular Risk Following Fertility Therapy
Dayan, N., Filion, K. B., Okano, M., Kilmartin, C., Reinblatt, S., Landry, T., Basso, O., & Udell, J. A. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.07.753 · Cited by 94 · see citing works
Self-citationFailure of fertility therapy and subsequent adverse cardiovascular events
Udell, J. A., Lu, H., & Redelmeier, D. A. (2017) · Canadian Medical Association Journal · doi:10.1503/cmaj.160744 · Cited by 63 · see citing works
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Niwa, K. (2018) · Korean Circulation Journal · doi:10.4070/kcj.2018.0070 · Cited by 41 · see citing works
Dayan, N., Lanes, A., WALKER, M. C., Spitzer, K. A., & Laskin, C. A. (2015) · Fertility and Sterility · doi:10.1016/j.fertnstert.2015.11.039 · Cited by 39 · see citing works
Self-citationCongenital Heart Disease and Women’s Health Across the Life Span: Focus on Reproductive Issues
Haberer, K., & Silversides, C. K. (2019) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2019.10.009 · Cited by 39 · see citing works
Self-citationInfertility, Infertility Treatment, and Cardiovascular Disease: An Overview
Smith, J., Vélez, M. P., & Dayan, N. (2021) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2021.09.002 · Cited by 32 · see citing works
Self-citationRossberg, N., Stangl, K., & Stangl, V. (2016) · European Journal of Preventive Cardiology · doi:10.1177/2047487316673143 · Cited by 31 · see citing works
Birth weight in pregnancies complicated by maternal heart disease
Cauldwell, M., Steer, P. J., Sterrenburg, M. D., Wallace, S., Malin, G. L., Ulivi, G., Everett, T. R., Jakes, A. D., Head, C., Mohan, A. R., et al. (2018) · Heart · doi:10.1136/heartjnl-2018-313551 · Cited by 29 · see citing works
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Self-citationPregnancy in women with congenital heart disease
D'Souza, R. D., Sermer, M., & Silversides, C. (2015) · Obstetric Medicine · doi:10.1177/1753495x14568055 · Cited by 24 · see citing works
Self-citationFamily Planning and Pregnancy Management in Adults with Congenital Heart Disease
Shum, K. K., Gupta, T., Canobbio, M. M., Durst, J. K., & Shah, S. B. (2018) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2018.08.001 · Cited by 15 · see citing works
Assisted Reproductive Technology Outcomes in Women With Heart Disease
Quien, M. M., Hausvater, A., Maxwell, S. M., & Weinberg, C. R. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.842556 · Cited by 13 · see citing works
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Cauldwell, M., Patel, R., Steer, P. J., Swan, L., Norman‐Taylor, J., Gatzoulis, M. Α., & Johnson, M. R. (2017) · American Heart Journal · doi:10.1016/j.ahj.2017.02.007 · Cited by 12 · see citing works
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English, K. M., Frise, C., Trinder, J., Cauldwell, M., Simpson, M., Adamson, D. L., Elton, C., Burns, G., Choudhary, M. K., Nathanson, M. H., et al. (2024) · Human Fertility · doi:10.1080/14647273.2023.2278295 · Cited by 7 · see citing works
van der Zande, J. A., Wander, G., Ramlakhan, K. P., Roos‐Hesselink, J. W., & Johnson, M. R. (2023) · Expert Review of Cardiovascular Therapy · doi:10.1080/14779072.2023.2223979 · Cited by 5 · see citing works
Special considerations in assisted reproductive technology for patients with cardiovascular disease
Cromack, S. C., Kalinowska, V., Boots, C. E., & Mendelson, M. A. (2025) · Fertility and Sterility · doi:10.1016/j.fertnstert.2025.03.021 · Cited by 3 · see citing works
Liu, W., & Yang, G. (2024) · BMC Cardiovascular Disorders · doi:10.1186/s12872-024-04180-8 · Cited by 3 · see citing works
Effect of Assisted Reproductive Technologies in Women With Cardiovascular Disease
Ardehali, A., Williams, C., Monagle, S. R., Cheung, A., Graham, A., Rychel, V., Oakes, J. K., Chau, A. M. T., Kiess, M. C., & Grewal, J. (2026) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2026.03.048 · Cited by 1 · see citing works
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Silversides, C. K., Colman, J. M., & Siu, S. C. (2019) · doi:10.1002/9781119409861.ch5
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Self-citation
- Authors
- Dayan, N., Laskin, C. A., Spitzer, K., Mason, J., Udell, J. A., Wald, R. M., Siu, S. C., Iten-Scott, T., & Silversides, C. K.
- Affiliations
- Mount Sinai Hospital (CA)
- Western University (CA)
- Corresponding author
- Silversides, Candice K.
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 2014-10
- Volume
- 64
- Issue
- 17
- Pages
- 1862-1864
- ISSN
- 0735-1097 (ISSN-L)
- OpenAlex
- W2071107071
- Cited by
- 34
- References
- 6
- Citations by year
- 2026: 7 · 2025: 3 · 2024: 3 · 2023: 4 · 2022: 2 · 2021: 2 · 2019: 3 · 2018: 3 · 2017: 3 · 2016: 1 · 2015: 3
- FWCI
- 1.61
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of the American College of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Scholarship@Western (Western University) (submittedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Issues in Pregnancy
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
- Health Sciences › Medicine › Obstetrics and Gynecology › COVID-19 Impact on Reproduction
- Keywords
- pregnancy complications, heart disease, infertility treatment, assisted reproduction, in vitro fertilization, intrauterine insemination, ovulation induction
- MeSH terms
- Adult, Female, Heart Diseases, Humans, Infant, Newborn, Infertility, Pregnancy, Pregnancy Complications, Cardiovascular, Pregnancy Outcome, Retrospective Studies, Treatment Outcome, Reproductive Techniques, Assisted
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