The DOI matches its Crossref record; 82 of the 82 references it cites were found in a registry or an index.
The Myth of the “Vulnerable Plaque”
Open accessAbstract
The cardiovascular science community has pursued the quest to identify vulnerable atherosclerotic plaque in patients for decades, hoping to prevent acute coronary events. However, despite major advancements in imaging technology that allow visualization of rupture-prone plaques, clinical studies have not demonstrated improved risk prediction compared to traditional approaches. Considering the complex relationship between plaque rupture and acute coronary event risk suggested by pathology studies and confirmed by clinical investigations, these results are not surprising. This review summarizes the evidence supporting a multifaceted hypothesis of the natural history of atherosclerotic plaque rupture. Managing patients at risk of suffering acute coronary events mandates a greater focus on the atherosclerotic disease burden, rather than on features of individual plaques.
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1 retracted
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RetractedPrediction of coronary heart disease using risk factor categories
Wilson, P. W. F., D’Agostino, R. B., Levy, D., Belanger, A. M., Silbershatz, H., & Kannel, W. B. (1998) · Circulation · doi:10.1161/01.cir.97.18.1837 · Cited by 9,581
Heart Disease and Stroke Statistics—2014 Update: A Report From the American Heart Association
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Intensive versus Moderate Lipid Lowering with Statins after Acute Coronary Syndromes
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Fractional Flow Reserve versus Angiography for Guiding Percutaneous Coronary Intervention
Tonino, P. A. L., De Bruyne, B., Pijls, N. H. J., Siebert, U., Ikeno, F., van `t Veer, M., Klauss, V., Manoharan, G., Engstrøm, T., Oldroyd, K. G., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0807611 · Cited by 4,260
A Prospective Natural-History Study of Coronary Atherosclerosis
Stone, G. W., Maehara, A., Lansky, A. J., de Bruyne, B., Cristea, E., Mintz, G. S., Mehran, R., McPherson, J., Farhat, N., Marso, S. P., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1002358 · Cited by 3,276
Coronary Calcium as a Predictor of Coronary Events in Four Racial or Ethnic Groups
Detrano, R., Guerci, A. D., Carr, J. J., Bild, D. E., Burke, G., Folsom, A. R., Liu, K., Shea, S., Szklo, M., Bluemke, D. A., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa072100 · Cited by 2,989
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Mechanisms of plaque formation and rupture
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Pathology of the Vulnerable Plaque
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Cited by
The changing landscape of atherosclerosis
Libby, P. (2021) · Nature · doi:10.1038/s41586-021-03392-8 · Cited by 2,873
Motwani, M., Dey, D., Berman, D. S., Germano, G., Achenbach, S., Al-Mallah, M. H., Andreini, D., Budoff, M. J., Cademartiri, F., Callister, T. Q., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw188 · Cited by 692
Testosterone Treatment and Coronary Artery Plaque Volume in Older Men With Low Testosterone
Budoff, M. J., Ellenberg, S. S., Lewis, C. E., Mohler, E. R., Wenger, N. K., Bhasin, S., Barrett-Connor, E., Swerdloff, R. S., Stephens-Shields, A., Cauley, J. A., et al. (2017) · JAMA · doi:10.1001/jama.2016.21043 · Cited by 376
Coronary Artery Calcium Scoring
Blaha, M. J., Mortensen, M. B., Kianoush, S., Tota-Maharaj, R., & Cainzos-Achirica, M. (2017) · JACC: Cardiovascular Imaging · doi:10.1016/j.jcmg.2017.05.007 · Cited by 276
Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques
Langley, S. R., Willeit, K., Didangelos, A., Matic, L. P., Skroblin, P., Barallobre-Barreiro, J., Lengquist, M., Rungger, G., Kapustin, A., Kedenko, L., et al. (2017) · Journal of Clinical Investigation · doi:10.1172/jci86924 · Cited by 174
Metadata
- Authors
- Arbab-Zadeh, A., & Fuster, V.
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 2015-03
- Volume
- 65
- Issue
- 8
- Pages
- 846-855
- ISSN
- 0735-1097 (ISSN-L)
- OpenAlex
- W1565401187
- Cited by
- 434
- References
- 82
- FWCI
- 49.08
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
