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Cited by 438

The DOI matches its Crossref record; 49 of the 49 references it cites were found in a registry or an index.

Cardiac Troponin for Assessment of Myocardial Injury in COVID-19

Open access
Sandoval, Yader, Januzzi, James L., Jaffe, Allan S.·2020·Journal of the American College of Cardiology

Abstract

Increases in cardiac troponin indicative of myocardial injury are common in patients with coronavirus disease-2019 (COVID-19) and are associated with adverse outcomes such as arrhythmias and death. These increases are more likely to occur in those with chronic cardiovascular conditions and in those with severe COVID-19 presentations. The increased inflammatory, prothrombotic, and procoagulant responses following severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection increase the risk for acute nonischemic myocardial injury and acute myocardial infarction, particularly type 2 myocardial infarction, because of respiratory failure with hypoxia and hemodynamic instability in critically ill patients. Myocarditis, stress cardiomyopathy, acute heart failure, and direct injury from SARS-CoV-2 are important etiologies, but primary noncardiac conditions, such as pulmonary embolism, critical illness, and sepsis, probably cause more of the myocardial injury. The structured use of serial cardiac troponin has the potential to facilitate risk stratification, help make decisions about when to use imaging, and inform stage categorization and disease phenotyping among hospitalized COVID-19 patients.

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Metadata

Authors
Sandoval, Y., Januzzi, J. L., & Jaffe, A. S.
Venue
Journal of the American College of Cardiology
Publisher
Elsevier BV
Published
2020-09
Volume
76
Issue
10
Pages
1244-1258
ISSN
0735-1097 (ISSN-L)
OpenAlex
W3082810171
Cited by
438
References
49
FWCI
10.68
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Cardiac Troponin for Assessment of Myocardial Injury in COVID-19. https://app.cochat.ai/papers/10.1016/j.jacc.2020.06.068
The paper
Sandoval, Y., Januzzi, J. L., & Jaffe, A. S. (2020). Cardiac Troponin for Assessment of Myocardial Injury in COVID-19. Journal of the American College of Cardiology. https://doi.org/10.1016/j.jacc.2020.06.068

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.