Moving Beyond the Model
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AI implementation for real-world impact depends not only on algorithm accuracy but also on designing, testing, monitoring and adapting systems to ensure proper reporting, follow-up and outcomes.
“AI implementation for real-world impact depends not only on algorithm accuracy but also on designing, testing, monitoring and adapting systems to ensure proper reporting, follow-up and outcomes.17”
From Prognostication and clinical opportunities with AI for coronary artery calcium: a scoping review (2026) · cites this paper as [17]
Using established frameworks for AI maturity in cardiovascular care, the majority of studies remain at stage 1 (Initial Development and Validation), with only limited progress to stage 2 (Implementation in Real World Settings).
“Using established frameworks for AI maturity in cardiovascular care,17 the majority of studies remain at stage 1 (Initial Development and Validation), with only limited progress to stage 2 (Implementation in Real World Settings).”
From Prognostication and clinical opportunities with AI for coronary artery calcium: a scoping review (2026) · cites this paper as [17]
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Cites
Huang, C.-X., Li, S.-X., Caraballo, C., Masoudi, F., Rumsfeld, J., Spertus, J., Normand, S.-L. T., Mortazavi, B., & Krumholz, H. (2021) · Circulation. Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.120.007526 · Cited by 73 · see citing works
Self-citationDhingra, L. S., Aminorroaya, A., Sangha, V., Pedroso, A. F., Shankar, S. V., Coppi, A., Foppa, M., Brant, L. C. C., Barreto, S. M., Ribeiro, A. L. P., et al. (2025) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2025.01.030 · Cited by 53 · see citing works
Self-citationKany, S., Rämö, J. T., Playford, D. A., Strange, G. A., Hou, C. R., Jurgens, S. J., Nauffal, V. D., Cunningham, J. W., Lau, E. S., Butte, A. J., et al. (2025) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2025.01.035 · Cited by 9 · see citing works
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Research works printed but not linked: 1
- [4]4. Bedi S., Cui H., Fuentes M., et al. MedHELM: Holistic evaluation of large language models for medical tasks. arXiv. 2025. 2505.23802.http://arxiv.org/abs/2505.23802. Go to Citation Google Scholar Podcast cover Editor's Page: September 9, 2025 | JACC Harlan Krumholz September 3, 2025 View full text|Download PDF Now Reading: Moving Beyond the Model: Our Perspective on Meaningful AI Research in Cardiovascular Care Share NEXT ARTICLE Influence of Type 2 Diabetes on the Effects of Tirzepatide in Patients With Heart Failure and a Preserved Ejection Fraction With Obesity Next JACC EDITOR'S PAGE Editor's Page: September 9, 2025 | JACC 00:00:00
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Zheng, X., Zou, H., Wu, L., Dong, P., Yuan, W., & Chen, Y. (2025) · International Journal of Nursing Sciences · doi:10.1016/j.ijnss.2025.10.007 · Cited by 7 · see citing works
Zhao, J., Tang, Y., Li, S., Wang, K., Tao, J., Chen, C., Zhou, J., Cui, L., Wang, Y., Huang, C., et al. (2026) · BMC Medicine · doi:10.1186/s12916-026-04768-1 · Cited by 4 · see citing works
Self-citationGuiding the AI Revolution in Cardiovascular Medicine
Krumholz, H. M. (2025) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2025.08.021 · Cited by 2 · see citing works
Self-citationAI as a tool, not a replacement, in vascular medicine
Rosenzveig, A., & Tefera, L. T. (2025) · Vascular Medicine · doi:10.1177/1358863x251399581 · Cited by 2 · see citing works
AI-ECG Detection of Structural Heart Disease in the Community Setting
Poterucha, T. J., Hughes, J. W., Brener, M. I., Chuang, M. L., Hamid, N. B., Snyder, C., Thompson, J. B., Ungarten, J., Takahashi, K., Lindman, B. R., et al. (2026) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2026.06.013 · Cited by 1 · see citing works
Self-citationPrognostication and clinical opportunities with AI for coronary artery calcium: a scoping review
McDonald, V. J. F., Parsa, S., Mastrodicasa, D., Rodriguez, F., Langlotz, C., Maron, D. J., Sandhu, A. T., Dudum, R., & Jain, S. S. (2026) · BMJ Digital Health & AI · doi:10.1136/bmjdh-2026-000053
Self-citationDo Performance Metrics for Echocardiographic AI Reflect Clinical Reality?
Zheng, T., Qin, Z., Pan, K. Q., & Liu, H. (2026) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2025.09.1611
Nolin-Lapalme, A., Tastet, O., Sowa, A., Delfrate, J., Adib, I. E., Morisset, J., Ahuja, R., Banerjee, R., Lessard, M.-G., Vadeboncœur, A., et al. (2026) · Journal of Electrocardiology · doi:10.1016/j.jelectrocard.2026.154359
Self-citationKassim, S. S., Feng, L. B., Rudin, P. N. F. A., Ibrahim, K. S., Ahmad, W. A. W., Fong, A. Y. Y., Cheen, S., & Malek, S. (2026) · Digital Health · doi:10.1177/20552076261426306
Barbieri, A., Mantovani, F., Malaguti, M., & Bursi, F. (2026) · Journal of Cardiovascular Echography · doi:10.4103/jcecho.jcecho_29_26
Chen, Y., Qin, X., & Chen, S. (2026) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2026.1838415
Lin, Z., HUANG, X., Yan, Y., Zheng, X., Wang, W., & Su, G. (2026) · International Nursing Review · doi:10.1111/inr.70217
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- Authors
- Jain, S. S., Mortazavi, B. J., Chan You, S., Yao, X., Lam, C. S. P., Elias, P., Poterucha, T. J., Avram, R., Tison, G. H., Pirruccello, J., Huang, C., Wiens, J., Schwamm, L., Ruan, X., Dunn, J., Luo, Y., Spatz, E. S., & Krumholz, H. M.
- Affiliations
- Stanford Cardiovascular Institute (US)
- Yale New Haven Hospital (US)
- Mayo Clinic (US)
- National University of Singapore (SG)
- NewYork–Presbyterian Hospital (US)
- Montreal Heart Institute (CA)
- University of California, San Francisco (US)
- University of Michigan (US)
- Yale University (US)
- The University of Texas Health Science Center at Houston (US)
- Duke University (US)
- Northwestern University (US)
- Corresponding author
- Jain, Sneha S.
- ORCID
- Venue
- JACC
- Publisher
- Elsevier BV
- Published
- 2025-09
- Volume
- 86
- Issue
- 10
- Pages
- 691-695
- ISSN
- 0735-1097 (ISSN-L)
- OpenAlex
- W4413883017
- Cited by
- 13
- References
- 3
- Citations by year
- 2026: 10 · 2025: 3
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of the American College of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Clinical practice guidelines implementation
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health and Medical Research Impacts
- Health Sciences › Medicine › Surgery › Coronary Interventions and Diagnostics
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