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Rhinosinusitis: Establishing definitions for clinical research and patient care
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“In addition, patients must have objective evidence of sinonasal inflammation on either nasal endoscopy (polyps, edema, mucopurulent rhinorrhea) or on CT scans of the sinuses.137,138,266,267”
From International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (2018) · cites this paper as [267]
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“CRS is an inflammatory condition of the sinonasal cavity persisting for more than 12 weeks with at least 2 symptoms of nasal obstruction and congestion, mucopurulent nasal drainage (anterior or posterior), facial pressure or pain, and anosmia/hyposmia.1,137,138,266,267”
From International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (2018) · cites this paper as [267]
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“CRS is divided into 2 main phenotypic groups: CRSwNP and CRSsNP.”
From International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (2018) · cites this paper as [267]
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“ARS is defined as the sudden onset of sinonasal symptoms with associated sinonasal inflammation that lasts less than 4 weeks.1,137,138,266,267”
From International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (2018) · cites this paper as [267]
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“Symptoms include nasal congestion, nasal obstruction or nasal discharge, and facial pressure or pain, or anosmia/hyposmia.”
From International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (2018) · cites this paper as [267]
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Wise, S. K., Lin, S. Y., Toskala, E., Orlandi, R. R., Akdis, C. A., Alt, J. A., Azar, A., Baroody, F. M., Bachert, C., Canonica, G. W., et al. (2018) · International Forum of Allergy & Rhinology · doi:10.1002/alr.22073 · Cited by 557
Self-citation
Metadata
- Authors
- Meltzer, E. O., Hamilos, D. L., Hadley, J. A., Lanza, D. C., Marple, B. F., Nicklas, R. A., Bachert, C., Baraniuk, J., Baroody, F. M., Benninger, M. S., Brook, I., Chowdhury, B. A., Druce, H. M., Durham, S., Ferguson, B., Gwaltney, J. M., Kaliner, M., Kennedy, D. W., Lund, V., Naclerio, R., Pawankar, R., Piccirillo, J. F., Rohane, P., Simon, R., Slavin, R. G., Togias, A., Wald, E. R., & Zinreich, S. J.
- Affiliations
- Allergy and Asthma Medical Group and Research Center (US)
- Harvard University (US)
- University of Rochester (US)
- Florida Institute of Oceanography (US)
- The University of Texas Southwestern Medical Center (US)
- George Washington University (US)
- Ghent University (BE)
- Georgetown University (US)
- University of Chicago (US)
- Henry Ford Health (US)
- Walter Reed National Military Medical Center (US)
- Rutgers New Jersey Medical School (US)
- Imperial College London (GB)
- University of Pittsburgh (US)
- University of Virginia (US)
- University of Pennsylvania (US)
- University College London (GB)
- Nippon Medical School (JP)
- Washington University in St. Louis (US)
- Celgene (United States) (US)
- Scripps Clinic (US)
- Saint Louis University (US)
- Johns Hopkins University (US)
- Corresponding author
- Meltzer, Eli O.
- ORCID
- Venue
- Journal of Allergy and Clinical Immunology
- Publisher
- Elsevier BV
- Published
- 2004-12
- Volume
- 114
- Issue
- 6
- Pages
- 155-212
- ISSN
- 0091-6749 (ISSN-L)
- PMC
- PMC7119142
- OpenAlex
- W2129761445
- Cited by
- 854
- References
- 363
- Citations by year
- 2026: 13 · 2025: 23 · 2024: 12 · 2023: 20 · 2022: 33 · 2021: 22 · 2020: 45 · 2019: 39 · 2018: 46 · 2017: 39 · 2016: 54 · 2015: 51 · 2014: 55 · 2013: 55 · 2012: 59
- FWCI
- 36.27
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Allergy and Clinical Immunology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Ghent University Academic Bibliography (Ghent University) (submittedVersion)
- Funders
- National Institutes of Health
- Georgetown University
- Topics
- Health Sciences › Medicine › Otorhinolaryngology › Sinusitis and nasal conditions
- Health Sciences › Medicine › Surgery › Nasal Surgery and Airway Studies
- Health Sciences › Medicine › Infectious Diseases › Otolaryngology and Infectious Diseases
- Keywords
- sinusitis, clinical definition, consensus definition, acute bacterial rhinosinusitis, allergic fungal rhinosinusitis, clinical trial design, quality of life instruments, radiographic evaluation, diagnosis
- MeSH terms
- Clinical Trials as Topic, Patient Care, Humans, Rhinitis, Sinusitis, Guidelines as Topic
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