Segmental Bronchoprovocation in Allergic Rhinitis Patients Affects Mast Cell and Basophil Numbers in Nasal and Bronchial Mucosa

BRAUNSTAHL, GERT-JAN; OVERBEEK, SHELLEY E.; FOKKENS, WYTSKE J.; KLEINJAN, ALEX; McEUEN, ALAN R.; WALLS, ANDREW F.; HOOGSTEDEN, HENK C.; PRINS, JAN–BAS

doi:10.1164/ajrccm.164.5.2006082

Segmental Bronchoprovocation in Allergic Rhinitis Patients Affects Mast Cell and Basophil Numbers in Nasal and Bronchial Mucosa

Mast cells and basophils are cells that play an important role in the initiation and control of allergic inflammation in asthma and rhinitis. This study was undertaken to determine the presence and dynamics of mast cells and basophils in the nasal and bronchial mucosa of allergic rhinitis patient…