Cited by 237Asthma and respiratory diseasesRespiratory and Cough-Related ResearchOccupational exposure and asthma

The DOI matches its Crossref record; 165 of the 165 references it cites were found in a registry or an index.

Airway injury as a mechanism for exercise-induced bronchoconstriction in elite athletes

Anderson, Sandra D., Kippelen, Pascale·2008·Journal of Allergy and Clinical Immunology

DOI 10.1016/j.jaci.2008.05.001

Open this paper in CoChat — free account

Abstract

Exercise-induced bronchoconstriction (EIB) is a consequence of evaporative water loss in conditioning the inspired air. The water loss causes cooling and dehydration of the airway surface. One acute effect of dehydration is the release of mediators, such as prostaglandins, leukotrienes, and histamine, that can stimulate smooth muscle, causing contraction and a change in vascular permeability. Inspiring cold air increases dehydration of the surface area and causes changes in bronchial blood flow. This article proposes that the pathogenesis of EIB in elite athletes relates to the epithelial injury arising from breathing poorly conditioned air at high flows for long periods of time or high volumes of irritant particles or gases. The evidence to support this proposal comes from many markers of injury. The restorative process after injury involves plasma exudation and movement of cells into the airways, a process repeated many times during a season of training. This process has the potential to expose smooth muscle to a wide variety of plasma- and cell-derived substances. The exposure to these substances over time can lead to an alteration in the contractile properties of the smooth muscle, making it more sensitive to mediators of bronchoconstriction. It is proposed that cold-weather athletes have airway hyperresponsiveness (AHR) to pharmacologic agents as a result of epithelial injury. In those who are allergic, AHR can also be expressed as EIB. The role of beta(2)-receptor agonists in inhibiting and enhancing the development of AHR and EIB is discussed.

Integrity signals

Registry

Crossref · 10.1016/j.jaci.2008.05.001

Cites

165 of 165 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Mast-Cell Infiltration of Airway Smooth Muscle in Asthma
Brightling, C. E., Bradding, P. H., Symon, F. A., Holgate, S. T., Wardlaw, A. J., & Pavord, I. D. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa012705 · Cited by 1,240
Direct activation of capsaicin receptors by products of lipoxygenases: Endogenous capsaicin-like substances
Hwang, S. W., Cho, H., Kwak, J., Lee, S.-Y., Kang, C.-J., Jung, J., Cho, S., Min, K. H., Suh, Y., Kim, D., et al. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.11.6155 · Cited by 1,047
Immune function in sport and exercise
Gleeson, M. (2007) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00008.2007 · Cited by 1,016
Non-eosinophilic asthma: importance and possible mechanisms
Douwes, J. E. (2002) · Thorax · doi:10.1136/thorax.57.7.643 · Cited by 639
The role of the mast cell in the pathophysiology of asthma
Bradding, P., Walls, A. F., & Holgate, S. T. (2006) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2006.02.039 · Cited by 573
Infectious episodes in runners before and after the Los Angeles Marathon.
Nieman, D. C., Johanssen, L. M., Lee, J. W., & Arabatzis, K. (1990) · PubMed · Cited by 530
Heterogeneity of Airway Inflammation in Persistent Asthma
Gibson, P. G., Simpson, J. L., & SALTOS, N. (2001) · CHEST Journal · doi:10.1378/chest.119.5.1329 · Cited by 528
The mechanism of exercise-induced asthma is …
Anderson, S. D., & Daviskas, E. (2000) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2000.109822 · Cited by 500
Self-citation
Molecular mechanisms of β2-adrenergic receptor function, response, and regulation
Johnson, M. (2005) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2005.11.012 · Cited by 384
Self-reported symptoms and exercise-induced asthma in the elite athlete
Rundell, K. W., Im, J., MAYERS, L. B., Wilber, R. L., SZMEDRA, L., & SCHMITZ, H. R. (2001) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-200102000-00006 · Cited by 345

Show all 165 references

Research works printed but not linked: 1

Sue-Chu, 2002, Airway responsiveness to methacholine (Mch), adenosine 5-monophosphate (AMP), mannitol (Man), eucapnic voluntary hyperpnea (EVH) and sport specific field exercise challenge (Ex) in cross country ski athletes, Eur Respir J, 20, 410s

Sorted by citations

Vitamin C for preventing and treating the common cold
Hemilä, H., & Chalker, E. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000980.pub4 · Cited by 869
Emerging role of 12/15-Lipoxygenase (ALOX15) in human pathologies
Singh, N. K., & Rao, G. N. (2018) · Progress in Lipid Research · doi:10.1016/j.plipres.2018.11.001 · Cited by 363
Pathogenesis, prevalence, diagnosis, and management of exercise-induced bronchoconstriction: a practice parameter
Weiler, J. M., Anderson, S. D., RANDOLPH, C. C., Bonini, S., Craig, T., Pearlman, D. S., Rundell, K. W., Silvers, W. S., Storms, W. W., Bernstein, D. I., et al. (2010) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2010.09.021 · Cited by 224
Self-citation
Vitamin C for preventing and treating the common cold
Hemilä, H., Chalker, E., & Douglas, B. (2007) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000980.pub3 · Cited by 182
Exercise-induced bronchoconstriction update—2016
Weiler, J. M., Brannan, J. D., RANDOLPH, C. C., Hallstrand, T. S., Parsons, J. P., Silvers, W. S., Storms, W. W., Zeiger, J. S., Bernstein, D. I., Blessing-Moore, J., et al. (2016) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2016.05.029 · Cited by 189
Asthma, Airway Inflammation and Epithelial Damage in Swimmers and Cold-Air Athletes
Bougault, V., Turmel, J., St-Laurent, J., Bertrand, M., & Boulet, L.-P. (2009) · European Respiratory Journal · doi:10.1183/09031936.00117708 · Cited by 170
Health problems in cold work
MÄKINEN, T. M., & HASSI, J. (2009) · Industrial Health · doi:10.2486/indhealth.47.207 · Cited by 166
Indirect Challenge Tests
Anderson, S. D. (2010) · CHEST Journal · doi:10.1378/chest.10-0116 · Cited by 167
Self-citation
Exercise-induced bronchoconstriction: prevalence, pathophysiology, patient impact, diagnosis and management
Aggarwal, B., Mulgirigama, A., & Berend, N. (2018) · npj Primary Care Respiratory Medicine · doi:10.1038/s41533-018-0098-2 · Cited by 139
Respiratory health of elite athletes – preventing airway injury: a critical review
Kippelen, P., Fitch, K. D., Anderson, S. D., Bougault, V., Boulet, L., Rundell, K. W., Sue‐Chu, M., & McKenzie, D. C. (2012) · British Journal of Sports Medicine · doi:10.1136/bjsports-2012-091056 · Cited by 135
Self-citation
Nutrition and Athlete Immune Health: New Perspectives on an Old Paradigm
Walsh, N. P. (2019) · Sports Medicine · doi:10.1007/s40279-019-01160-3 · Cited by 155
GEMA 5.3. Spanish Guideline on the Management of Asthma
Plaza, V., Alobid, I., Rodríguez, C. Á., Blanco‐Aparicio, M., Ferreira, J., García, G., Gómez‐Outes, A., Garín, N., Ruiz, F. G., Requena, A. H., et al. (2023) · Open Respiratory Archives · doi:10.1016/j.opresp.2023.100277 · Cited by 121
Bronchial epithelial damage after a half-marathon in nonasthmatic amateur runners
Chimenti, L., Morici, G., Paternò, A., Santagata, R., Bonanno, A., Profita, M., Riccobono, L., Bellia, V., & Bonsignore, M. R. (2010) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00053.2010 · Cited by 86
Mechanisms of exercise‐induced bronchoconstriction in athletes: Current perspectives and future challenges
Couto, M., Kurowski, M., Moreira, A. M., Bullens, D. M. A., Carlsen, K. ‐., Delgado, L., Kowalski, M. L., & Seys, S. (2017) · Allergy · doi:10.1111/all.13224 · Cited by 87
Airway dysfunction in elite athletes - an occupational lung disease?
Price, O. J., Ansley, L., Menzies-Gow, A. N., Cullinan, P., & Hull, J. H. (2013) · Allergy · doi:10.1111/all.12265 · Cited by 85
Effect of inspired air conditions on exercise-induced bronchoconstriction and urinary CC16 levels in athletes
Bolger, C., Tufvesson, E., Anderson, S. D., Devereux, G. S., Ayres, J. G., Bjermer, L. H., Sue‐Chu, M., & Kippelen, P. (2011) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00113.2011 · Cited by 80
Self-citation
Is the healthy respiratory system built just right, overbuilt, or underbuilt to meet the demands imposed by exercise?
Dempsey, J. A., Gerche, A. L., & Hull, J. H. (2020) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00444.2020 · Cited by 79
Airway injury during high-level exercise
Kippelen, P., & Anderson, S. D. (2012) · British Journal of Sports Medicine · doi:10.1136/bjsports-2011-090819 · Cited by 79
Self-citation
Asthma, allergy and the Olympics: a 12-year survey in elite athletes
Bonini, M., Gramiccioni, C., Fioretti, D., Ruckert, B., Rinaldi, M., Akdis, C., Todaro, A., Palange, P., Carlsen, K.-H., Pelliccia, A., et al. (2015) · Current Opinion in Allergy & Clinical Immunology · doi:10.1097/aci.0000000000000149 · Cited by 76
Airway hyperresponsiveness to methacholine, adenosine 5-monophosphate, mannitol, eucapnic voluntary hyperpnoea and field exercise challenge in elite cross-country skiers
Sue‐Chu, M., Brannan, J. D., Anderson, S. D., Chew, N. Y. K., & Bjermer, L. H. (2010) · British Journal of Sports Medicine · doi:10.1136/bjsm.2009.071043 · Cited by 72
Self-citation
Diagnosis of exercise-induced bronchoconstriction: eucapnic voluntary hyperpnoea challenges identify previously undiagnosed elite athletes with exercise-induced bronchoconstriction
Dickinson, J., MCCONNELL, A. K., & Whyte, G. P. (2010) · British Journal of Sports Medicine · doi:10.1136/bjsm.2010.072520 · Cited by 74
Airway dysfunction in swimmers: Table 1
Bougault, V., & Boulet, L. (2012) · British Journal of Sports Medicine · doi:10.1136/bjsports-2011-090821 · Cited by 67
Vitamin C may alleviate exercise-induced bronchoconstriction: a meta-analysis
Hemilä, H. (2013) · BMJ Open · doi:10.1136/bmjopen-2012-002416 · Cited by 63
Airway hyperresponsiveness in elite swimmers: Is it a transient phenomenon?
Bougault, V., Turmel, J., & Boulet, L. (2010) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2010.11.003 · Cited by 62
Japanese guidelines for childhood asthma 2020
Arakawa, H., Adachi, Y., Ebisawa, M., Fujisawa, T., Arakawa, H., Adachi, Y., Ebisaw, M., Fujisawa, T., Akasawa, A., Inoue, T., et al. (2020) · Allergology International · doi:10.1016/j.alit.2020.02.005 · Cited by 62
Misdiagnosis of exercise‐induced bronchoconstriction in professional soccer players
Ansley, L., Kippelen, P., Dickinson, J. W., & Hull, J. H. (2011) · Allergy · doi:10.1111/j.1398-9995.2011.02762.x · Cited by 60
Self-citation
Exercise-induced bronchoconstriction: new evidence in pathogenesis, diagnosis and treatment
Bonini, M., & Palange, P. (2015) · Asthma Research and Practice · doi:10.1186/s40733-015-0004-4 · Cited by 69
Combined inhalation of beta2‐agonists improves swim ergometer sprint performance but not high‐intensity swim performance
Kalsen, A., Hostrup, M., Bangsbo, J., & Backer, V. (2013) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/sms.12096 · Cited by 58
High BMI is related to higher incidence of asthma, while a fish and fruit diet is related to a lower–
Uddenfeldt, M., Janson, C., Lampa, E., Leander, M., Norbäck, D., Larsson, L., & Rask‐Andersen, A. (2010) · Respiratory Medicine · doi:10.1016/j.rmed.2009.12.013 · Cited by 58
Effects of Polluted Air on Cardiovascular and Hematological Parameters After Progressive Maximal Aerobic Exercise
Kargarfard, M., Shariat, A., Shaw, B. S., Shaw, I., Lam, E. T. C., Kheiri, A., Eatemadyboroujeni, A., & Tamrin, S. B. M. (2015) · Lung · doi:10.1007/s00408-014-9679-1 · Cited by 57
Prevalence of lower airway dysfunction in athletes: a systematic review and meta-analysis by a subgroup of the IOC consensus group on ‘acute respiratory illness in the athlete’
Price, O. J., Sewry, N. A., Schwellnus, M. P., Backer, V., Reier‐Nilsen, T., Bougault, V., Pedersen, L., Chenuel, B. J., Larsson, K., & Hull, J. H. (2021) · British Journal of Sports Medicine · doi:10.1136/bjsports-2021-104601 · Cited by 60
Airway Endothelial Dysfunction in Asthma and Chronic Obstructive Pulmonary Disease: A Challenge for Future Research
Wanner, A., & Mendes, E. S. (2010) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201001-0038pp · Cited by 55
Exercise but not mannitol provocation increases urinary Clara cell protein (CC16) in elite swimmers
Romberg, K., Bjermer, L. H., & Tufvesson, E. (2010) · Respiratory Medicine · doi:10.1016/j.rmed.2010.07.012 · Cited by 55
Hyperpnea-Induced Bronchoconstriction and Urinary CC16 Levels in Athletes
Bolger, C., Tufvesson, E., Sue‐Chu, M., Devereux, G. S., Ayres, J. G., Bjermer, L. H., & Kippelen, P. (2010) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e31820750d8 · Cited by 53
Self-citation
Exercise and Asthma
Côté, A., Turmel, J., & Boulet, L. (2018) · Seminars in Respiratory and Critical Care Medicine · doi:10.1055/s-0037-1606215 · Cited by 52
Asthma Phenotypes as a Guide for Current and Future Biologic Therapies
Hamilton, D., & Lehman, H. K. (2019) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-019-08760-x · Cited by 54
Practicing Sport in Cold Environments: Practical Recommendations to Improve Sport Performance and Reduce Negative Health Outcomes
Gatterer, H., Dünnwald, T., Turner, R., Csapo, R., Schobersberger, W., Burtscher, M., Faulhaber, M., & Kennedy, M. D. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18189700 · Cited by 60
Role of leukotrienes in exercise-induced bronchoconstriction
Hallstrand, T. S., & Henderson, W. R. (2008) · Current Allergy and Asthma Reports · doi:10.1007/s11882-009-0003-8 · Cited by 49
Mechanisms and Biomarkers of Exercise-Induced Bronchoconstriction
Kippelen, P., Anderson, S. D., & Hallstrand, T. S. (2018) · Immunology and Allergy Clinics of North America · doi:10.1016/j.iac.2018.01.008 · Cited by 49
Self-citation
Environmental conditions, air pollutants, and airway cells in runners: A longitudinal field study
Chimenti, L., Morici, G., Paternò, A., Bonanno, A., Vultaggio, M., Bellia, V., & Bonsignore, M. R. (2009) · Journal of Sports Sciences · doi:10.1080/02640410902946493 · Cited by 48
Assessment of EIB
Anderson, S. D., & Kippelen, P. (2013) · Immunology and Allergy Clinics of North America · doi:10.1016/j.iac.2013.02.006 · Cited by 47
Self-citation
An update on exercise-induced bronchoconstriction with and without asthma
Randolph, C. (2009) · Current Allergy and Asthma Reports · doi:10.1007/s11882-009-0064-8 · Cited by 46
Increase of club cell (Clara) protein (CC16) in plasma and urine after exercise challenge in asthmatics and healthy controls, and correlations to exhaled breath temperature and exhaled nitric oxide
Tufvesson, E., Svensson, H., Ankerst, J., & Bjermer, L. H. (2013) · Respiratory Medicine · doi:10.1016/j.rmed.2013.08.004 · Cited by 45
Pathogenesis of Exercise-Induced Bronchoconstriction
Kippelen, P., & Anderson, S. D. (2013) · Immunology and Allergy Clinics of North America · doi:10.1016/j.iac.2013.02.002 · Cited by 41
Self-citation
Food allergies and food-induced anaphylaxis: role of cofactors
Shin, M. (2020) · Korean Journal of Pediatrics · doi:10.3345/cep.2020.01088 · Cited by 40
Environmental influence on the prevalence and pattern of airway dysfunction in elite athletes
Lévai, Í., Hull, J. H., Loosemore, M., Greenwell, J., Whyte, G. P., & Dickinson, J. W. (2016) · Respirology · doi:10.1111/resp.12859 · Cited by 39
Exercise-Induced Bronchoconstriction and the Air We Breathe
Rundell, K. W., Smoliga, J. M., & Bougault, V. (2018) · Immunology and Allergy Clinics of North America · doi:10.1016/j.iac.2018.01.009 · Cited by 36
Airways exudation of plasma macromolecules: Innate defense, epithelial regeneration, and asthma
Persson, C. G. A. (2018) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2018.07.037 · Cited by 35
Exercise-induced bronchoconstriction in elite or endurance athletes:
Atchley, T. J., & Smith, D. M. (2020) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2020.01.023 · Cited by 35
Exercise-induced asthma
Parsons, J. P., & Mastronarde, J. G. (2008) · Current Opinion in Pulmonary Medicine · doi:10.1097/mcp.0b013e32831da8ab · Cited by 35
The effect of vitamin C on bronchoconstriction and respiratory symptoms caused by exercise: a review and statistical analysis
Hemilä, H. (2014) · Allergy Asthma and Clinical Immunology · doi:10.1186/1710-1492-10-58 · Cited by 33
Exhaled breath condensate pH decreases during exercise‐induced bronchoconstriction
Bikov, A., Gálffy, G., Tamási, L., Bartusek, D., Antus, B., Losonczy, G., & Horváth, I. (2014) · Respirology · doi:10.1111/resp.12248 · Cited by 32
Effect of Continuous Positive Airway Pressure on Airway Reactivity in Asthma. A Randomized, Sham-controlled Clinical Trial
Holbrook, J. T., Sugar, E. A., Brown, R. H., Drye, L. T., Irvin, C. G., Schwartz, A. R., Tepper, R. S., Wise, R. A., Yasin, R. Z., & Busk, M. F. (2016) · Annals of the American Thoracic Society · doi:10.1513/annalsats.201601-043oc · Cited by 32
International Olympic Committee (IOC) consensus statement on acute respiratory illness in athletes part 2: non-infective acute respiratory illness
Schwellnus, M. P., Adami, P. E., Bougault, V., Budgett, R., Clemm, H. H., Derman, W. E., Erdener, U., Fitch, K. D., Hull, J. H., McIntosh, C., et al. (2022) · British Journal of Sports Medicine · doi:10.1136/bjsports-2022-105567 · Cited by 32
Bronchial provocation testing: the future
Anderson, S. D., & Brannan, J. D. (2010) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/aci.0b013e3283423183 · Cited by 31
Self-citation
Work Group Report: Perspectives in Diagnosis and Management of Exercise-Induced Bronchoconstriction in Athletes
Greiwe, J. C., Cooke, A., Nanda, A., Epstein, S. Z., Wasan, A. N., Shepard, K. V., Capão-Filipe, M., Nish, A., Rubin, M., Gregory, K. L., et al. (2020) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2020.05.020 · Cited by 30
Cold air exercise screening for exercise induced bronchoconstriction in cold weather athletes
Kennedy, M. D., Steele, A. R., Parent, É., & Steinback, C. D. (2019) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2019.103262 · Cited by 32
Male infertility and somatic health — insights into lipid damage as a mechanistic link
Burke, N. D., Nixon, B., Roman, S. D., Schjenken, J. E., Walters, J. L. H., Aitken, R. J., & Bromfield, E. G. (2022) · Nature Reviews Urology · doi:10.1038/s41585-022-00640-y · Cited by 31
The effect of air pollution on diurnal variation of performance in anaerobic tests, cardiovascular and hematological parameters, and blood gases on soccer players following the Yo–Yo Intermittent Recovery Test Level-1
Boussetta, N., Abedelmalek, S., Aloui, K., & Souissi, N. (2017) · Chronobiology International · doi:10.1080/07420528.2017.1325896 · Cited by 32
Exercise-Induced Bronchospasm
Molis, M. A., & Molis, W. E. (2010) · Sports Health A Multidisciplinary Approach · doi:10.1177/1941738110373735 · Cited by 29
Screening for Exercise-Induced Bronchoconstriction in College Athletes
Parsons, J. P., Cosmar, D., Phillips, G. S., Kaeding, C. C., Best, T. M., & Mastronarde, J. G. (2012) · Journal of Asthma · doi:10.3109/02770903.2011.652329 · Cited by 28
Exercise‐induced bronchospasm related to different phenotypes of rhinitis without asthma in primary schoolchildren: the French Six Cities Study
Caillaud, D. M., Horo, K., Baïz, N., Banerjee, S., Charpin, D., Lavaud, F., Frederic de, B. L. A. Y., Rahérison, C., & Annesi‐Maesano, I. (2014) · Clinical & Experimental Allergy · doi:10.1111/cea.12310 · Cited by 28
Management of Exercise-Induced Bronchoconstriction in Athletes
Koya, T., Ueno, H., Hasegawa, T., Arakawa, M., & Kikuchi, T. (2020) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2020.03.011 · Cited by 28
Australian Association for Exercise and Sports Science position statement on exercise and asthma
Morton, A. R., & Fitch, K. D. (2011) · Journal of science and medicine in sport · doi:10.1016/j.jsams.2011.02.009 · Cited by 28
Neutrophilic inflammation is associated with altered airway hydration in stable asthmatics
Loughlin, C. E., Esther, C. R., Lazarowski, E. R., Alexis, N. E., & Peden, D. B. (2009) · Respiratory Medicine · doi:10.1016/j.rmed.2009.07.002 · Cited by 28
Effect of Acu-TENS on post-exercise expiratory lung volume in subjects with asthma—A randomized controlled trial
Ngai, S. P. C., JONES, A. Y. M., Hui-Chan, C. W. Y., Ko, F. W. S., & Hui, D. S. C. (2009) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2009.06.010 · Cited by 27
Effects of a heat and moisture exchanger on respiratory function and symptoms post–cold air exercise
Frischhut, C., Kennedy, M. D., Niedermeier, M., & Faulhaber, M. (2019) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/sms.13603 · Cited by 26
Diagnosis and management of allergy and respiratory disorders in sport: An EAACI task force position paper
Price, O. J., Walsted, E. S., Bonini, M., Brannan, J. D., Bougault, V., Carlsen, K., Couto, M., Kippelen, P., Moreira, A. M., Pité, H., et al. (2022) · Allergy · doi:10.1111/all.15431 · Cited by 30
Self-citation
Mechanisms and Management of Exercise-Induced Asthma in Elite Athletes
Ali, Z., Norsk, P., & Ulrik, C. S. (2012) · Journal of Asthma · doi:10.3109/02770903.2012.676123 · Cited by 25
Upper airway comorbidities of asthma
Jung, C., Buchheit, K. M., Bochenek, G., Dzoba, E. A., & Cho, S. (2024) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2024.10.007 · Cited by 24
Pathophysiology of bronchoconstriction
Bácsi, A., Pan, L., Ba, X., & Boldogh, I. R. (2015) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/aci.0000000000000232 · Cited by 24
Repeated airway constrictions in mice do not alter respiratory function
Mailhot-Larouche, S., Deschênes, L., Gazzola, M., Lortie, K., Henry, C., Brook, B. S., Morissette, M. C., & Bossé, Y. (2018) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01073.2017 · Cited by 24
Exercise in Sub-zero Temperatures and Airway Health: Implications for Athletes With Special Focus on Heat-and-Moisture-Exchanging Breathing Devices
Hanstock, H. G., Ainegren, M., & Stenfors, N. (2020) · Frontiers in Sports and Active Living · doi:10.3389/fspor.2020.00034 · Cited by 27
The role of impulse oscillometry in detecting airway dysfunction in athletes
Price, O. J., Ansley, L., Bikov, A., & Hull, J. H. (2015) · Journal of Asthma · doi:10.3109/02770903.2015.1063647 · Cited by 24
Exercise-induced bronchoconstriction
Pongdee, T., & Li, J. T. (2013) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2013.02.002 · Cited by 24
School environmental factors are predictive for exercise-induced symptoms in children
Stelmach, I., Cichalewski, Ł., Majak, P., Smejda, K., Podlecka, D., Jerzyńska, J., & Stelmach, W. (2016) · Respiratory Medicine · doi:10.1016/j.rmed.2016.01.010 · Cited by 24
The environment, the airway, and the athlete
Sacha, J. J., & Quinn, J. M. (2010) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2010.06.004 · Cited by 26
Epithelial regulation of eicosanoid production in asthma
Hallstrand, T. S., Lai, Y., Henderson, W. R., Altemeier, W. A., & Gelb, M. H. (2012) · Pulmonary Pharmacology & Therapeutics · doi:10.1016/j.pupt.2012.02.004 · Cited by 23
What Makes a Difference in Exercise-Induced Bronchoconstriction: An 8 Year Retrospective Analysis
Park, H., Jung, J., Cho, S., Min, K., & Kang, H. (2014) · PLoS ONE · doi:10.1371/journal.pone.0087155 · Cited by 22
Roles of plasma exudation in asthma and COPD
Persson, C. G. A., & Uller, L. (2009) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2009.03373.x · Cited by 22
Advances in the diagnosis of exercise-induced bronchoconstriction
Price, O. J., Hull, J. H., & Ansley, L. (2014) · Expert Review of Respiratory Medicine · doi:10.1586/17476348.2014.890517 · Cited by 24
Asthma prevalence in German Olympic athletes: A comparison of winter and summer sport disciplines
Selge, C., Thomas, S., Nowak, D., Radon, K., & Wolfarth, B. (2016) · Respiratory Medicine · doi:10.1016/j.rmed.2016.07.008 · Cited by 23
Exercise-induced bronchoconstriction in the 21st century.
Anderson, S. D. (2011) · PubMed · Cited by 20
Self-citation
Salivary antimicrobial protein responses during multistage ultramarathon competition conducted in hot environmental conditions
Gill, S. K., Teixeira, A. M., Rama, L. M. P. L., Rosado, F., Hankey, J., Scheer, V., Robson-Ansley, P. J., & Costa, R. J. S. (2013) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2013-0005 · Cited by 22
Diagnostic Exercise Challenge Testing
RANDOLPH, C. C. (2011) · Current Allergy and Asthma Reports · doi:10.1007/s11882-011-0225-4 · Cited by 19
Respiratory disorders in endurance athletes – how much do they really have to endure?
Bussotti, M., Marchese, G., & Marco, S. D. (2014) · Open Access Journal of Sports Medicine · doi:10.2147/oajsm.s57828 · Cited by 20
Effect of Fish Oil-Derived Omega-3 Polyunsaturated Fatty Acid Supplementation on Exercise-Induced Bronchoconstriction and Immune Function in Athletes
Mickleborough, T. D., Lindley, M. R., & Montgomery, G. S. (2008) · The Physician and Sportsmedicine · doi:10.3810/psm.2008.12.7 · Cited by 19
Exercise-Induced Bronchospasm in Elite Athletes
Pigakis, K., Stavrou, V. T., Pantazopoulos, I. N., Daniil, Z. D., Kontopodi, A., & Gourgoulianis, K. I. (2022) · Cureus · doi:10.7759/cureus.20898 · Cited by 18
Exercise-Induced Wheeze, Urgent Medical Visits, and Neighborhood Asthma Prevalence
Mainardi, T. R., Mellins, R. B., Miller, R. L., Acosta, L., Cornell, A. G., Hoepner, L., Quinn, J. W., Yan, B., Chillrud, S. N., Olmedo, O. E., et al. (2012) · PEDIATRICS · doi:10.1542/peds.2012-1072 · Cited by 17
Nonpharmacologic Strategies to Manage Exercise-Induced Bronchoconstriction
Dickinson, J. W., Amirav, I., & Hostrup, M. (2018) · Immunology and Allergy Clinics of North America · doi:10.1016/j.iac.2018.01.012 · Cited by 19
Asthma in elite athletes
Elers, J., Pedersen, L., & Backer, V. (2011) · Expert Review of Respiratory Medicine · doi:10.1586/ers.11.28 · Cited by 17
Pollen-induced oxidative DNA damage response regulates miRNAs controlling allergic inflammation
Aguilera-Aguirre, L., Hao, W., Pan, L., Li, X., Saavedra‐Molina, A., Bácsi, A., Radak, Z. O., Sur, S. A., Brasier, A. R., Ba, X., et al. (2017) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00141.2017 · Cited by 17
Asthma in Elite Athletes
Price, O. J., & Hull, J. H. (2014) · Clinical Pulmonary Medicine · doi:10.1097/cpm.0000000000000030 · Cited by 18
The impact of a heat and moisture exchange mask on respiratory symptoms and airway response to exercise in asthma
Jackson, A. R., Hull, J. H., Hopker, J., Fletcher, H. V., Gowers, W., Birring, S. S., & Dickinson, J. W. (2020) · ERJ Open Research · doi:10.1183/23120541.00271-2019 · Cited by 16
Bronchial Provocation Testing for the Identification of Exercise-Induced Bronchoconstriction
Brannan, J. D., & Kippelen, P. (2020) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2020.03.034 · Cited by 15
Self-citation
Salt Intake, Asthma, and Exercise-Induced Bronchoconstriction: A Review
Mickleborough, T. D. (2010) · The Physician and Sportsmedicine · doi:10.3810/psm.2010.04.1769 · Cited by 15
Exercise-induced bronchoconstriction: The effects of montelukast, a leukotriene receptor antagonist
Kemp, J. P. (2009) · Therapeutics and Clinical Risk Management · doi:10.2147/tcrm.s4830 · Cited by 15
Asthma and exercise-induced respiratory symptoms in the athlete
Boulet, L., Turmel, J., & Côté, A. (2016) · Current Opinion in Pulmonary Medicine · doi:10.1097/mcp.0000000000000339 · Cited by 15
Exploring physiological parameters in ski mountaineering during world cup races
Gaston, A.-F., Peiro, A. M., Hapková, I., & Durand, F. (2019) · International Journal of Performance Analysis in Sport · doi:10.1080/24748668.2019.1597399 · Cited by 15
Stimulus and mechanisms of exercise-induced bronchoconstriction
Anderson, S. D., & Kippelen, P. (2010) · Breathe · doi:10.1183/18106838.0701.025 · Cited by 15
Self-citation

Authors: Anderson, S. D., & Kippelen, P.
Affiliations: Royal Prince Alfred Hospital (AU)
University of Aberdeen (GB)
Corresponding author: Anderson, Sandra D.
ORCID: Anderson, Sandra D.
Kippelen, Pascale
Venue: Journal of Allergy and Clinical Immunology
Publisher: Elsevier BV
Published: 2008-08
Volume: 122
Issue: 2
Pages: 225-235
ISSN: 0091-6749 (ISSN-L)
DOI: 10.1016/j.jaci.2008.05.001
OpenAlex: W1966370024
Semantic Scholar: 4b75678f6bce41311a4bde4f6ec899f7a7355e94
Cited by: 237
References: 165
Citations by year: 2026: 8 · 2025: 6 · 2024: 7 · 2023: 5 · 2022: 13 · 2021: 5 · 2020: 17 · 2019: 12 · 2018: 17 · 2017: 11 · 2016: 16 · 2015: 8 · 2014: 10 · 2013: 19 · 2012: 18
FWCI: 1.99
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Journal of Allergy and Clinical Immunology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory and Cough-Related Research
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Occupational exposure and asthma
Keywords: exercise-induced bronchoconstriction, airway injury, airway epithelial injury, airway cooling, airway hyperresponsiveness, elite athletes, plasma exudation, beta2-adrenergic agonists, allergic airway disease, bronchial blood flow, airway irritants
MeSH terms: Adrenergic beta-Agonists, Asthma, Exercise-Induced, Bronchi, Capillary Permeability, Epithelial Cells, Humans, Inflammation, Mast Cells, Muscle, Smooth, Sports, Exercise, Eicosanoids, Bronchoconstriction, Bronchoconstrictor Agents, Methacholine Chloride, Bronchial Hyperreactivity

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Airway injury as a mechanism for exercise-induced bronchoconstriction in elite athletes

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks