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Detecting perinatal common mental disorders in Ethiopia: Validation of the self-reporting questionnaire and Edinburgh Postnatal Depression Scale
Abstract
Background The cultural validity of instruments to detect perinatal common mental disorders (CMD) in rural, community settings has been little-investigated in developing countries.Methods Semantic, content, technical, criterion and construct validity of the Edinburgh Postnatal Depression Scale (EPDS) and Self-Reporting Questionnaire (SRQ) were evaluated in perinatal women in rural Ethiopia. Gold-standard measure of CMD was psychiatric assessment using the Comprehensive Psychopathological Rating Scale (CPRS). Community-based, convenience sampling was used. An initial validation study (n=101) evaluated both EPDS and SRQ. Subsequent validation was of SRQ alone (n=119).Results EPDS exhibited poor validity; area under the receiver operating characteristic (AUROC) curve of 0.62 (95%CI 0.49 to 0.76). SRQ-20 showed better validity as a dimensional scale, with AUROC of 0.82 (95%CI 0.68 to 0.96) and 0.70 (95%CI 0.57 to 0.83) in the two studies. The utility of SRQ in detecting 'cases' of CMD was not established, with differing estimates of optimal cut-off score: three and above in Study 1 (sensitivity 85.7%, specificity 75.6%); seven and above in Study 2 (sensitivity 68.4%, specificity 62%). High convergent validity of SRQ as a dimensional measure was demonstrated in a community survey of 1065 pregnant women.Limitations Estimation of optimal cut-off scores and validity coefficients for detecting CMD was limited by sample size.Conclusions EPDS demonstrated limited clinical utility as a screen for perinatal CMD in this rural, low-income setting. The SRQ-20 was superior to EPDS across all domains for evaluating cultural equivalence and showed validity as a dimensional measure of perinatal CMD.
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“For this qualitative study, purposive sampling was conducted based on gender, age, area of residence, and level of mental distress, as indicated by scores on the culturally validated Self-Reporting Questionnaire, 20-item version [33–36].”
From Experience and perceptions of mental ill-health in people with epilepsy in rural Ethiopia: A qualitative study (2024) · cites this paper as [35]
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Metadata
- Authors
- Hanlon, C., Medhin, G., Alem, A., Araya, M., Abdulahi, A., Hughes, M., Tesfaye, M., Wondimagegn, D., Patel, V., & Prince, M.
- Affiliations
- King's College London (GB)
- Addis Ababa University (ET)
- London School of Hygiene & Tropical Medicine (GB)
- Corresponding author
- Hanlon, Charlotte
- ORCID
- Venue
- Journal of Affective Disorders
- Publisher
- Elsevier BV
- Published
- 2008-06
- Volume
- 108
- Issue
- 3
- Pages
- 251-262
- ISSN
- 0165-0327 (ISSN-L)
- OpenAlex
- W1974901321
- Cited by
- 278
- References
- 46
- Citations by year
- 2026: 10 · 2025: 12 · 2024: 18 · 2023: 21 · 2022: 20 · 2021: 32 · 2020: 25 · 2019: 17 · 2018: 13 · 2017: 11 · 2016: 14 · 2015: 13 · 2014: 14 · 2013: 17 · 2012: 8
- FWCI
- 8.27
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Affective Disorders (publishedVersion)
- PubMed (publishedVersion)
- Research Portal (King's College London) (submittedVersion)
- Funders
- Wellcome Trust (GR071643MA)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Health Sciences › Nursing › Research and Theory › Health Education and Validation
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Keywords
- Edinburgh Postnatal Depression Scale, Self-Reporting Questionnaire, SRQ-20, screening tool validation, cultural validity, rural Ethiopia, pregnant women, cut-off values, convergent validity, dimensional metrology
- MeSH terms
- Adult, Mental Disorders, Catchment Area, Health, Ethiopia, Female, Humans, Mass Screening, Perinatology, Puerperal Disorders, Surveys and Questionnaires, Reproducibility of Results, Prevalence, Depression, Postpartum
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