Outcomes in patients with and without capacity in electroconvulsive therapy
Abstract
Background Electroconvulsive therapy (ECT) is an effective treatment for severe mental illness but access is limited for patients lacking consent capacity. We aimed to compare the symptomatic, cognitive, quality of life (QOL) and functional outcomes of patients with and without capacity receiving ECT for schizophrenia, depression or mania.Methods Patients prescribed ECT in a single center had their clinical outcomes pre and post ECT compared with repeated measures ANOVAs. Differences in demographic, clinical characteristics and ECT treatment between the group lacking and having capacity were examined using independent t-tests for continuous variables and chi-squared tests for categorical variables.Results 75.1% of 175 patients lacked capacity. The group lacking capacity had overall poorer cognitive and global functioning pre ECT but higher QOL. Objective psychiatric symptom ratings after ECT improved similarly between groups. Mood, cognition, QOL and function improved in both groups, with more improvement in mood and function in the group lacking capacity and a trend towards greater cognitive improvement (p = 0.051).Limitations Subgroup analysis by diagnosis was not done due to smaller sample sizes in each group. Cognition was assessed with a general screening instrument not a full neuropsychological assessment.Conclusions ECT is a safe and effective treatment for schizophrenia, bipolar mania and depression, and may provide similar or greater benefits in patients lacking capacity to consent, compared to those with capacity. These results support the provision of a framework for substitute decision making in the patients' best interests for ECT in patients unable to provide their own consent.
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For ECT, more than half of patients lacked capacity (between 51.7% to 75.1%).
“They found that more than half of patients lacked capacity (between 51.7% to 75.1%).”
From Decision making capacity for treatment in psychiatric inpatients: a systematic review and meta-analysis (2024) · cites this paper as Tor et al., 2020
Both capacitous and incapacitous patients generally improved in their psychiatric symptoms following ECT treatment.
“Both capacitous and incapacitous patients generally improved in their psychiatric symptoms following treatment.”
From Decision making capacity for treatment in psychiatric inpatients: a systematic review and meta-analysis (2024) · cites this paper as Tor et al., 2020
Depression was also associated with incapacity.
“and depression (G.Owen et al., 2009;G. S. Owen et al., 2008G. S. Owen et al., , 2011;;Tor et al., 2020).”
From Decision making capacity for treatment in psychiatric inpatients: a systematic review and meta-analysis (2024) · cites this paper as Tor et al., 2020
Cognitive performance is relevant to capacity, although the MMSE and MOCA are screening tests so conclusions must be considered with caution.
“Other studies also found that cognitive performance is relevant to capacity, although they used the Mini Mental State Examination (MMSE) (Kahn et al., 2009) or Montreal Cognitive Assessment (MOCA) (Tor et al., 2020) as measures, which are both screening tests, so their conclusions must be considered with caution.”
From Decision making capacity for treatment in psychiatric inpatients: a systematic review and meta-analysis (2024) · cites this paper as Tor et al., 2020
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- Authors
- Tor, P.-C., Tan, F. J. S., Martin, D., & Loo, C.
- Affiliations
- Institute of Mental Health (SG)
- Black Dog Institute (AU)
- Corresponding author
- Tor, Phern-Chern
- Venue
- Journal of Affective Disorders
- Publisher
- Elsevier BV
- Published
- 2020-04
- Volume
- 266
- Pages
- 151-157
- ISSN
- 0165-0327 (ISSN-L)
- OpenAlex
- W3002324017
- Cited by
- 27
- References
- 56
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 3 · 2023: 3 · 2022: 6 · 2021: 6 · 2020: 4
- FWCI
- 3.46
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Affective Disorders (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Electroconvulsive Therapy Studies
- Social Sciences › Psychology › Clinical Psychology › Healthcare Decision-Making and Restraints
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Keywords
- electroconvulsive therapy, decision-making capacity, informed consent, substitute decision-making, schizophrenia, bipolar mania, depression, cognitive outcomes, quality of life, functional outcome, psychiatric symptoms
- MeSH terms
- Cognition, Electroconvulsive Therapy, Humans, Neuropsychological Tests, Quality of Life, Schizophrenia, Treatment Outcome
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