Pediatrician and behavioral clinician-delivered screening, brief intervention and referral to treatment: Substance use and depression outcomes
Open accessAbstract
Background Early intervention for adolescent substance use and mental health problems may mitigate potential harm. We examined patient outcomes from a pragmatic trial of two modalities of delivering Screening, Brief Intervention and Referral to Treatment (SBIRT) and Usual Care in pediatric primary care. Methods All clinic pediatricians (n=52) were randomized to three arms: 1) pediatrician-only, in which pediatricians were trained to deliver SBIRT; 2) embedded behavioral clinician (BC), in which pediatricians were trained to refer eligible adolescents to a BC who administered SBIRT; and 3) Usual Care (UC). Using electronic health record data, changes in past year substance use and depression symptoms between index visit and next screening visit were examined across treatment arms. Results Among patients who endorsed substance use and/or depression symptoms or were eligible for further assessments, brief interventions and referrals based on clinician assessment at index visit, 648 patients (mean age=15.2[SD=1.2]) were rescreened at a follow-up visit between 6 months and 2 years later. Among all patients, self-reported substance use rates did not differ over time or across arms, and depression symptoms increased over time. The embedded-BC arm had lower odds of having depression symptoms at follow-up than the physician-only arm, and lower odds than the UC arm though not significant; we found no differences between the pediatrician-only and UC arms. Conclusions The increase in depression symptoms over time highlights this population’s vulnerability and the importance of developing appropriate interventions. An embedded BC in pediatric primary care trained in SBIRT may benefit patients with depression symptoms.
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SBIRT are delivered to U.S. adolescents most frequently in pediatric primary care settings as a public health approach to preventing substance use and mental health symptoms.
“Screening, brief intervention, and referral to treatment (SBIRT) are delivered to U.S. adolescents most frequently in pediatric primary care settings as a public health approach to preventing substance use and mental health symptoms [15,16].”
From Young Adult Substance Use and Healthcare Use Associated With Screening, Brief Intervention and Referral to Treatment in Pediatric Primary Care. (2022) · cites this paper as [15]
The Introduction describes SBIRT as early intervention for adolescent substance use and discusses integrating substance use and mental health care into primary care. The Methods describe its delivery in a U.S. pediatric clinic. Neither passage establishes that pediatric primary care is where U.S. adolescents most frequently receive SBIRT. (LLM, conf=0.84)
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Cites
Merikangas, K. R., He, J.-P., Burstein, M., Swanson, S. A., Avenevoli, S., Cui, L., Benjet, C., Georgiades, K., & Swendsen, J. (2010) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2010.05.017 · Cited by 6,278 · see citing works
Motivational Interviewing: Helping People Change
Tober, G. (2013) · Alcohol and Alcoholism · doi:10.1093/alcalc/agt010 · Cited by 4,267 · see citing works
Bellg, A. J., Treatment Fidelity Workgroup of the NIH Behavior Change Consortium, Borrelli, B., Resnick, B., Hecht, J., Minicucci, D. S., Ory, M., Ogedegbe, G., Orwig, D., Ernst, D., et al. (2004) · Health Psychology · doi:10.1037/0278-6133.23.5.443 · Cited by 2,620 · see citing works
(2013) · Cited by 2,393 · see citing works
Mental Health Surveillance Among Children — United States, 2013–2019
Bitsko, R. H., Claussen, A. H., Lichstein, J., Black, L. I., Jones, S. E., Danielson, M. L., Hoenig, J. M., Davis Jack, S. P., Brody, D. J., Gyawali, S., et al. (2022) · MMWR Supplements · doi:10.15585/mmwr.su7102a1 · Cited by 1,723 · see citing works
National trends in the prevalence and treatment of depression in adolescents and young adults.
Mojtabai, R., Olfson, M., & Han, B. (2016) · Pediatrics · doi:10.1542/peds.2016-1878 · Cited by 1,424 · see citing works
Validity of the CRAFFT Substance Abuse Screening Test Among Adolescent Clinic Patients
Knight, J. R., Sherritt, L., Shrier, L. A., Harris, S. K., & Chang, G. (2002) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpedi.156.6.607 · Cited by 786 · see citing works
(2013) · PubMed · Cited by 770 · see citing works
US Preventive Services Task Force (2010) · PEDIATRICS · doi:10.1542/peds.2009-2037 · Cited by 619 · see citing works
Asarnow, J. R., Rozenman, M., Wiblin, J., & Zeltzer, L. (2015) · JAMA Pediatrics · doi:10.1001/jamapediatrics.2015.1141 · Cited by 545 · see citing works
Evidence Base Update of Psychosocial Treatments for Child and Adolescent Depression
Weersing, V. R., Jeffreys, M., Do, M.-C. T., Schwartz, K. T. G., & Bolano, C. (2017) · Journal of Clinical Child & Adolescent Psychology · doi:10.1080/15374416.2016.1220310 · Cited by 505 · see citing works
Brief alcohol interventions for adolescents and young adults: A systematic review and meta-analysis
Tanner-Smith, E. E., & Lipsey, M. W. (2015) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2014.09.001 · Cited by 468 · see citing works
Improving mental health access for low-income children and families in the primary care setting.
Hodgkinson, S., Godoy, L., Beers, L. S., & Lewin, A. (2017) · Pediatrics · doi:10.1542/peds.2015-1175 · Cited by 451 · see citing works
Analysis of cluster randomized trials in primary care: a practical approach
Campbell, M. K., Mollison, J., Steen, N., Grimshaw, J. M., & Eccles, M. (2000) · Family Practice · doi:10.1093/fampra/17.2.192 · Cited by 327 · see citing works
Collaborative Care for Adolescents With Depression in Primary Care: A Randomized Clinical Trial
Richardson, L. P., Ludman, E., McCauley, E., Lindenbaum, J., Larison, C., Zhou, C., Clarke, G., Brent, D., & Katon, W. (2014) · JAMA · doi:10.1001/jama.2014.9259 · Cited by 281 · see citing works
D'Amico, E. J., Miles, J. N. V., Stern, S. A., & Meredith, L. S. (2008) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2007.08.008 · Cited by 231 · see citing works
Alegria, M., Carson, N. J., Goncalves, M., & Keefe, K. (2011) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2010.10.005 · Cited by 229 · see citing works
2014 Recommendations for Pediatric Preventive Health Care
COMMITTEE ON PRACTICE AND AMBULATORY MEDICINE, B. F. P. S. W. (2014) · Pediatrics · doi:10.1542/peds.2013-4096 · Cited by 169 · see citing works
Harris, S. K., Csémy, L., Sherritt, L., Starostova, O., Van Hook, S., Johnson, J., Boulter, S., Brooks, T., Carey, P., Kossack, R., et al. (2012) · Pediatrics · doi:10.1542/peds.2011-1624 · Cited by 163 · see citing works
Babor, T. F., Higgins-Biddle, J. C., Dauser, D., Higgins, P. S., & Burleson, J. A. (2005) · Journal of Studies on Alcohol · doi:10.15288/jsa.2005.66.361 · Cited by 148 · see citing works
Siu, A. L., & on behalf of the US Preventive Services Task Force (2016) · PEDIATRICS · doi:10.1542/peds.2015-4467 · Cited by 134 · see citing works
Mertens, J. R., Chi, F. W., Weisner, C. M., Satre, D. D., Ross, T. B., Allen, S., Pating, D., Campbell, C. I., Lu, Y. W., & Sterling, S. A. (2015) · Addiction Science & Clinical Practice · doi:10.1186/s13722-015-0047-0 · Cited by 127 · see citing works
Self-citationWalton, M. A., Resko, S., Barry, K. L., Chermack, S. T., Zucker, R. A., Zimmerman, M. A., Booth, B. M., & Blow, F. C. (2014) · Addiction · doi:10.1111/add.12469 · Cited by 111 · see citing works
Alcohol Screening and Brief Intervention for Youth: A Practitioner's Guide
(2011) · PsycEXTRA Dataset · doi:10.1037/e722082011-001 · Cited by 101 · see citing works
Sterling, S., Kline‐Simon, A. H., Wibbelsman, C. J., Wong, A., & Weisner, C. M. (2012) · Addiction Science & Clinical Practice · doi:10.1186/1940-0640-7-13 · Cited by 92 · see citing works
Self-citationWalton, M. A., Bohnert, K. M., Resko, S. M., Barry, K. L., Chermack, S. T., Zucker, R. A., Zimmerman, M. A., Booth, B. M., & Blow, F. C. (2013) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2013.04.020 · Cited by 88 · see citing works
Interventions for Adolescent Depression in Primary Care
Stein, R. E. K., Zitner, L., & Jensen, P. S. (2006) · PEDIATRICS · doi:10.1542/peds.2005-2086 · Cited by 87 · see citing works
Asarnow, J. R., Jaycox, L. H., Tang, L., Duan, N., LaBorde, A. P., Zeledon, L. R., Anderson, M., Murray, P. J., Landon, C., Rea, M. M., et al. (2009) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2009.08121909 · Cited by 85 · see citing works
Hoek, W., Marko, M., Fogel, J., Schuurmans, J., Gladstone, T., Bradford, N., Domanico, R., Fagan, B., Bell, C., Reinecke, M. A., et al. (2011) · Translational research · doi:10.1016/j.trsl.2011.07.006 · Cited by 73 · see citing works
Sterling, S., Kline‐Simon, A. H., Satre, D. D., Jones, A., Mertens, J. R., Wong, A., & Weisner, C. M. (2015) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/jamapediatrics.2015.3145 · Cited by 72 · see citing works
Self-citationParrish, K. H., Atherton, O. E., Quintana, A., Conger, R. D., & Robins, R. W. (2016) · Psychology of Addictive Behaviors · doi:10.1037/adb0000138 · Cited by 68 · see citing works
Motivational interviewing to reduce substance use in adolescents with psychiatric comorbidity
Brown, R. A., Abrantes, A. M., Minami, H., Prince, M. A., Bloom, E. L., Apodaca, T. R., Strong, D. R., Picotte, D. M., Monti, P. M., MacPherson, L., et al. (2015) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2015.06.016 · Cited by 42 · see citing works
Primary Care Provider Training in Screening, Assessment, and Treatment of Adolescent Depression
Fallucco, E. M., Seago, R. D., Cuffe, S. P., Kraemer, D. F., & Wysocki, T. (2015) · Academic Pediatrics · doi:10.1016/j.acap.2014.12.004 · Cited by 40 · see citing works
Kline‐Simon, A. H., Weisner, C. M., & Sterling, S. (2016) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2016.02.008 · Cited by 36 · see citing works
Self-citationPhysician Satisfaction With Integrated Behavioral Health in Pediatric Primary Care
Hine, J. F., Grennan, A., Menousek, K. M., Robertson, G. C., Valleley, R. J., & Evans, J. H. (2016) · Journal of Primary Care & Community Health · doi:10.1177/2150131916668115 · Cited by 33 · see citing works
Randomized Trial of Brief Office-Based Interventions to Reduce Adolescent Alcohol Use
Boekeloo, B. O., Jerry, J., Lee-Ougo, W. I., Worrell, K. D., Hamburger, E. K., Russek‐Cohen, E., & Snyder, M. H. (2004) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpedi.158.7.635 · Cited by 31 · see citing works
Embedding a Psychologist Into Primary Care Increases Access to Behavioral Health Services
Miller-Matero, L. R., Dubaybo, F., Ziadni, M. S., Feit, R., Kvamme, R., Eshelman, A. K., & Keimig, W. (2014) · Journal of Primary Care & Community Health · doi:10.1177/2150131914550831 · Cited by 30 · see citing works
A. Hulvershorn, L., D. Quinn, P., & L. Scott, E. (2015) · Current Drug Abuse Reviews · doi:10.2174/1874473708666150514102745 · Cited by 30 · see citing works
Babowitch, J. D., & Antshel, K. M. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.04.018 · Cited by 30 · see citing works
Gabel, S. (2010) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2010.06.007 · Cited by 22 · see citing works
Substance Misuse Among Adolescents
Subramaniam, G., & Volkow, N. D. (2014) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/jamapediatrics.2014.958 · Cited by 22 · see citing works
Integrating depression treatment within primary care improves outcomes in adolescents
Asarnow, J. R., & Rozenman, M. S. (2015) · Evidence-Based Mental Health · doi:10.1136/eb-2014-101994 · Cited by 5 · see citing works
Flagged first, then by citations
1 of the 43 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Harris, B. R., Maher, B. M., & Wentworth, L. (2022) · The Journal of Behavioral Health Services & Research · doi:10.1007/s11414-021-09780-2 · Cited by 58 · see citing works
What’s known about implementing co-located paediatric integrated care: a scoping review
Platt, R. E., Spencer, A. E., Burkey, M. D., Vidal, C., Polk, S., Bettencourt, A. F., Jain, S., Stratton, J., & Wissow, L. S. (2018) · International Review of Psychiatry · doi:10.1080/09540261.2018.1563530 · Cited by 43 · see citing works
Ni, Y., Bachtel, A., Nause, K., & Beal, S. J. (2021) · Journal of the American Medical Informatics Association · doi:10.1093/jamia/ocab116 · Cited by 33 · see citing works
Sterling, S., Parthasarathy, S., Jones, A., Weisner, C., Metz, V., Hartman, L., Saba, K., & Kline-Simon, A. H. (2022) · Journal of Adolescent Health · doi:10.1016/j.jadohealth.2021.11.033 · Cited by 33 · see citing works
“screening and assessment items, and clinical workflows, have been previously described elsewhere [15,37,38].”
BackgroundMethodSelf-citationHealth care use over 3 years after adolescent SBIRT
Sterling, S., Kline-Simon, A. H., Jones, A., Hartman, L., Saba, K., Weisner, C., & Parthasarathy, S. (2019) · Pediatrics · doi:10.1542/peds.2018-2803 · Cited by 34 · see citing works
Self-citationAdolescent SBIRT Practices Among Pediatricians in Massachusetts
Levy, S., Wiseblatt, A. F., Straus, J. H., Strother, H., Fluet, C. F., & Harris, S. K. (2019) · Journal of Addiction Medicine · doi:10.1097/adm.0000000000000551 · Cited by 31 · see citing works
Mitchell, S. G., Gryczynski, J., Schwartz, R. P., Kirk, A. S., Dušek, K., Oros, M. T., Hosler, C., O’Grady, K. E., & Brown, B. S. (2020) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2020.01.007 · Cited by 28 · see citing works
Alcohol Screening, Brief Intervention, and Referral to Treatment (SBIRT) for Girls and Women
Hammock, K. (2020) · Alcohol research · doi:10.35946/arcr.v40.2.07 · Cited by 29 · see citing works
Three-year outcomes after brief treatment of substance use and mood symptoms
Parthasarathy, S., Kline-Simon, A. H., Jones, A., Hartman, L., Saba, K., Weisner, C., & Sterling, S. (2021) · Pediatrics · doi:10.1542/peds.2020-009191 · Cited by 20 · see citing works
Self-citationAppleton, R., Barnett, P., Clarke, C., Yang, J., Begum, S., Edbrooke-Childs, J. H., Emptage, I., Foye, U., Griffiths, J., Hanson, I., et al. (2025) · BMC Medicine · doi:10.1186/s12916-025-04438-8 · Cited by 16 · see citing works
Beck, A., Dryburgh, N. S. J., Bennett, A., Shaver, N., Esmaeilisaraji, L., Skidmore, B., Patten, S. B., Bragg, H., Colman, I., Goldfield, G. S., et al. (2024) · Systematic Reviews · doi:10.1186/s13643-023-02447-3 · Cited by 18 · see citing works
Kuhns, L. M., Carlino, B., Greeley, K., Muldoon, A. L., Karnik, N. S., Thompson, H. M., Garofalo, R., & Rahmandar, M. H. (2020) · Substance Abuse Treatment Prevention and Policy · doi:10.1186/s13011-020-00276-4 · Cited by 14 · see citing works
Hostutler, C. A., Shahidullah, J. D., Mautone, J. A., Rybak, T. M., Okoroji, C., Bruni, T. P., Stephenson, K. G., Utset, L. V., Freeman, K. A., LaLonde, L., et al. (2024) · Journal of Pediatric Psychology · doi:10.1093/jpepsy/jsae038 · Cited by 14 · see citing works
Integrated Primary Care and Mental Health Service Utilization: A Meta-Analysis
Hostutler, C. A., Shahidullah, J. D., Rybak, T. M., Stephenson, K. G., Freeman, K. A., LaLonde, L., Danzo, S., Koval, E. T., Hughes, H., & Riley, A. R. (2025) · PEDIATRICS · doi:10.1542/peds.2025-071275 · Cited by 7 · see citing works
Addressing adolescent substance use in an urban pediatric federally qualified health center
Yonek, J. C., Velez, S., Satre, D. D., Margolis, K. L., Whittle, A., Jain, S., & Tolou‐Shams, M. (2021) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2021.108653 · Cited by 6 · see citing works
Self-citationTreatment of Opioid Use Disorder in Pediatric Medical Settings
Levy, S., & Camenga, D. R. (2019) · Current Addiction Reports · doi:10.1007/s40429-019-00272-0 · Cited by 6 · see citing works
Facilitators and Barriers to Care for Patients with Disabilities in Primary Pediatrics
Ayoub, M., Rava, J. A., Hunter, A. L., & Kuo, A. A. (2022) · Pediatric Annals · doi:10.3928/19382359-20220407-07 · Cited by 5 · see citing works
Hogue, A., Porter, N., Ozechowski, T. J., Becker, S. J., O’Grady, M. A., Bobek, M., Cerniglia, M., Ambrose, K., MacLean, A., Hadland, S. E., et al. (2024) · JMIR Research Protocols · doi:10.2196/54486 · Cited by 5 · see citing works
Appleton, R., Barnett, P., Clarke, C., Yang, J., Begum, S., Edbrooke-Childs, J. H., Emptage, I., Foye, U., Griffiths, J., Hanson, I., et al. (2025) · medRxiv · doi:10.1101/2025.02.07.25321864 · Cited by 4 · see citing works
Hadani, Y., Tarikogullari, I., Oesterle, T., McGinnis, M. T., Nidey, N., Lai, B., Kalata, A. H., Sharma, P., & Bormann, N. L. (2025) · American Journal on Addictions · doi:10.1111/ajad.70104 · Cited by 3 · see citing works
Harris, B. R., & Rich, J. H. (2021) · Journal of Social Work Practice in the Addictions · doi:10.1080/1533256x.2021.1935153 · Cited by 2 · see citing works
Bommersbach, T. J., Steelesmith, D. L., Xia, X., Olfson, M., & Fontanella, C. A. (2026) · Psychiatric Services · doi:10.1176/appi.ps.20250654 · Cited by 1 · see citing works
Suitability of Behavior Analysis in Pediatric Primary Care
LaLonde, L., Maragakis, A., Bruni, T. P., & Lancaster, B. M. (2021) · Springer eBooks · doi:10.1007/978-3-030-57969-2_9
Bonar, E. E., Goldstick, J. E., Philyaw-Kotov, M. L., Bourque, C. A., Woolford, S. J., Resnicow, K., Quigley, J. M., Wernette, G. T., Ahmed, S., Langlois, D. M., et al. (2025) · Contemporary Clinical Trials · doi:10.1016/j.cct.2025.108172
- Authors
- Sterling, S., Kline-Simon, A. H., Weisner, C., Jones, A., & Satre, D. D.
- Affiliations
- Kaiser Permanente (US)
- Corresponding author
- Sterling, Stacy
- Venue
- Journal of Adolescent Health
- Publisher
- Elsevier BV
- Published
- 2018-04
- Volume
- 62
- Issue
- 4
- Pages
- 390-396
- ISSN
- 1054-139X (ISSN-L)
- PMC
- PMC5866770
- OpenAlex
- W2787237529
- Semantic Scholar
- 9c8aa59763d71729188c65905e1fefc6535a87c5
- Cited by
- 24
- References
- 43
- Citations by year
- 2026: 1 · 2025: 5 · 2024: 3 · 2022: 3 · 2021: 4 · 2020: 4 · 2019: 3 · 2018: 1
- FWCI
- 2.34
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Adolescent Health (acceptedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- National Institute on Alcohol Abuse and Alcoholism (R01 AA016204)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Health Sciences › Health Professions › Speech and Hearing › Adolescent and Pediatric Healthcare
- Keywords
- SBIRT, adolescent substance use, adolescent depression, depressive symptoms, pediatric primary care, early intervention, rescreening, usual care comparison
- MeSH terms
- Pediatricians, Adolescent, Delivery of Health Care, Depression, Female, Humans, Male, Mass Screening, Primary Health Care, Referral and Consultation, Cognitive Behavioral Therapy, Substance-Related Disorders
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