Randomized controlled trial of primary care physician motivational interviewing versus brief advice to engage adolescents with an Internet-based depression prevention intervention: 6-month outcomes and predictors of improvement.
Open accessAbstract
We believe that primary care physicians could play a key role in engaging youth with a depression prevention intervention. We developed CATCH-IT (Competent Adulthood Transition with Cognitive Behavioral and Interpersonal Training), which is an adolescent Internet-based behavior change model. We conducted a randomized comparison of two approaches in engaging adolescents with the Internet intervention: primary care physician (PCP) motivational interview + CATCH-IT Internet program (MI) vs PCP brief advice + CATCH-IT Internet program (BA). The participants (N = 84) were recruited by screening for risk of depression in 13 primary care practices. We compared depressive disorder outcomes between groups and within groups over 6 months and examined the potential predictors and moderators of outcomes across both study arms. Depressive symptom scores declined from baseline to 6 weeks with these statistically significant reductions sustained at the 6 months follow-up in both groups. No significant interactions with treatment condition were found. However, by 6 months, the MI group demonstrated significantly fewer depressive episodes and reported less hopelessness as compared with the BA group. Hierarchical linear modeling regressions showed higher ratings of ease of use of the Internet program predicting lower depressive symptom levels over 6 months. In conclusion, a primary care/Internet-based intervention model among adolescents demonstrated reductions in depressed mood over 6 months and may result in fewer depressive episodes.
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MI delivered by a clinical psychologist with postgraduate MI-training improved treatment initiation and participation.
“MI delivered by a clinical psychologist with postgraduate MI-training improved treatment initiation and participation,31”
From Efficacy of Motivational Interviewing to Improve Utilization of Mental Health Services Among Youths With Chronic Medical Conditions: A Cluster Randomized Clinical Trial (2021) · cites this paper as [31]
The Introduction reports greater adherence to the Internet program in the MI group, supporting the participation part of the claim. But the Methods (Study design and Intervention overview; page unavailable) say primary care physicians delivered MI, not a clinical psychologist with postgraduate MI training. The cited passages do not establish improved treatment initiation. (LLM, conf=0.88)
Experimental — accuracy not yet measuredMI can be implemented in a busy schedule as an add-on conversation technique (additional 15-20 minutes) during regular appointments.
“MI can be implemented in a busy schedule as an add-on conversation technique (additional 15–20 minutes) during regular appointments, and can potentially improve treatment attendance31,54,55 and outcomes,56 encourage medication adherence,57,58 facilitate the transition to adult care,59 and reduce risk-taking behaviors.60”
From Efficacy of Motivational Interviewing to Improve Utilization of Mental Health Services Among Youths With Chronic Medical Conditions: A Cluster Randomized Clinical Trial (2021) · cites this paper as [31]
The Methods (Intervention overview; page unavailable) describe a physician interview using motivational interviewing in primary care, supporting its use as a conversation-based intervention. The paper does not say it added 15–20 minutes to a regular appointment or establish that it fits a busy schedule; it also describes preparatory questionnaires and motivational phone calls. (LLM, conf=0.82)
Experimental — accuracy not yet measured
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Abuwalla, Z., Clark, M. D., Burke, B. J., Tannenbaum, V., Patel, S., Mitacek, R., Gladstone, T. R. G., & Voorhees, B. W. V. (2017) · Internet Interventions · doi:10.1016/j.invent.2017.11.006 · Cited by 12 · see citing works
Malakouti, S. K., Rasouli, N., Rezaeian, M., Nojomi, M., Ghanbari, B., & Shahraki-Mohammadi, A. (2020) · PubMed Central · doi:10.34171/mjiri.34.85 · Cited by 11 · see citing works
Bourassa, K. A., McKibbin, C., Hartung, C. M., Bartholomew, K. L., Lee, A. A., Stevens, A. E., Buxton, Y., Slosser, A., & Andren, K. A. K. (2017) · Journal of Health Psychology · doi:10.1177/1359105316630136 · Cited by 10 · see citing works
Malakouti, S. K., Rasouli, N., rezaeean, M., Nojomi, M., Ghanbari, B., & Shahraki-Mohammadi, A. (2020) · Medical Journal of the Islamic Republic of Iran · doi:10.47176/mjiri.34.85 · Cited by 9 · see citing works
Soler, C. L., Vicente-Escudero, J. L., López-López, J. A., Alcántara-López, M., Martínez, A. C., Sáez, M. C., Fernández, V., & Sánchez‐Meca, J. (2024) · International Journal of Clinical and Health Psychology · doi:10.1016/j.ijchp.2024.100487 · Cited by 8 · see citing works
The Role of Human Support on Engagement in an Online Depression Prevention Program for Youth
Rogers, J., Gladstone, T. R. G., Voorhees, B. W. V., & Bunge, E. L. (2021) · Social Sciences · doi:10.3390/socsci10080285 · Cited by 6 · see citing works
Low-Intensity Online Intervention for Mental Distress Among Help-Seeking Young People in Hong Kong
Suen, Y. N., Hui, C. L. M., Lei, L. K. S., Leung, C. M., Wong, S. M. Y., Lai, G., Chau, E. H. S., Wong, M. T. H., Chan, S. K. W., Wong, G. H. Y., et al. (2025) · JAMA Network Open · doi:10.1001/jamanetworkopen.2024.54675 · Cited by 7 · see citing works
Kruger, J. R., Kim, P., Iyer, V., Marko-Holguin, M., Fogel, J., DeFrino, D. T., Gladstone, T. R. G., & Voorhees, B. W. V. (2017) · International Journal of Mental Health Promotion · doi:10.1080/14623730.2017.1308264 · Cited by 5 · see citing works
Need for Integrated Behavior Health Model in Primary Care
Cates, K., & Soares, N. S. (2021) · Pediatric Clinics of North America · doi:10.1016/j.pcl.2021.02.009 · Cited by 4 · see citing works
Ospina‐Pinillos, L., Krausz, R. M., & Hickie, I. B. (2021) · Springer eBooks · doi:10.1007/978-3-030-57296-9_128 · Cited by 3 · see citing works
Bjornstad, G. J., Sonthalia, S., Rouse, B., Freeman, L., Hessami, N., Dunne, J. H., & Axford, N. (2024) · Campbell Systematic Reviews · doi:10.1002/cl2.1376 · Cited by 3 · see citing works
Kammering, H., Cruz, J. A., Platzbecker, A. L., Reinauer, C., Förtsch, K., Krassuski, L. M., Viermann, R., Domhardt, M., Baumeister, H., Staab, D., et al. (2024) · BMC Pediatrics · doi:10.1186/s12887-024-04794-z · Cited by 4 · see citing works
Espinosa-Duque, D., Arcila, M. F., Ruiz, M. P., Jaramillo, J. C., Moessner, M., Bauer, S., & Krause, M. (2022) · CES Psicología · doi:10.21615/cesp.5428 · Cited by 2 · see citing works
Hoek, N. W. (2012) · Digital Academic REpository of VU University Amsterdam (Vrije Universiteit Amsterdam) · Cited by 2 · see citing works
Adolescents, Obesity, and Motivational Interviewing
Cheney, B. J. (2013) · Journal of Bioresource Management · Cited by 1 · see citing works
Ospina-Pinillos, L., Davenport, T., Diaz, A. M., Navarro-Mancilla, A., Scott, E., & Hickie, I. (2019) · doi:10.2196/preprints.14127 · Cited by 1 · see citing works
Effectiviteit van een extra contactmoment in het voortgezet onderwijs
Bannink, R., Broeren, S., Zwanenburg, E. J.-V., van As, E., Jansen, P. M. V. D. L. –., & Raat, H. (2015) · JGZ Tijdschrift voor jeugdgezondheidszorg · doi:10.1007/s12452-015-0017-7
Internet-Based Depression Prevention in Adolescents: A Systematic Review Protocol
Thummathai, K., Lasuka, D., Sethabouppha, H., & Chanprasit, C. (2013) · The JBI Database of Systematic Reviews and Implementation Reports · doi:10.11124/jbisrir-2013-991
Care for children of parents with depression
Hansen, K. (2014)
Psychopharmacological Treatment for Depression in Children and Adolescents
Chapman, M. R., Hughes, J. L., Kennard, B. D., Mayes, T. L., & Emslie, G. J. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-804394-3.00011-5
Jo, H. M., & Kim, S. (2017) · Research in Community and Public Health Nursing · doi:10.12799/jkachn.2017.28.3.260
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Peuters, C., Maenhout, L., Cardon, G., Paepe, A. L. D., DeSmet, A., Lauwerier, E., Leta, K., & Crombez, G. (2023) · doi:10.2196/preprints.45668
Kammering, H., Cruz, J. A., Platzbecker, A. L., Reinauer, C., Viermann, R., Domhardt, M., Baumeister, H., Förtsch, K., Krassuki, L., Staab, D., et al. (2023) · Research Square · doi:10.21203/rs.3.rs-2591650/v1
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Peuters, C., Maenhout, L., Cardon, G., Paepe, A. L. D., DeSmet, A., Lauwerier, E., Leta, K., & Crombez, G. (2024) · Figshare · doi:10.6084/m9.figshare.26658823
Peuters, C., Maenhout, L., Cardon, G., Paepe, A. L. D., DeSmet, A., Lauwerier, E., Leta, K., & Crombez, G. (2024) · Figshare · doi:10.6084/m9.figshare.26658811
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- Authors
- Hoek, W., Marko, M., Fogel, J., Schuurmans, J., Gladstone, T., Bradford, N., Domanico, R., Fagan, B., Bell, C., Reinecke, M. A., & Van Voorhees, B. W.
- Affiliations
- Vrije Universiteit Amsterdam (NL)
- University of Illinois Chicago (US)
- Brooklyn College (US)
- Wellesley College (US)
- John H. Stroger, Jr. Hospital of Cook County (US)
- University of North Carolina at Chapel Hill (US)
- Northwestern University (US)
- Venue
- Translational research
- Publisher
- Elsevier BV
- Published
- 2011-12
- Volume
- 158
- Issue
- 6
- Pages
- 315-325
- ISSN
- 1878-1810 (ISSN-L)
- 1931-5244
- PMC
- PMC6181117
- OpenAlex
- W2004693887
- Cited by
- 73
- References
- 50
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 9 · 2023: 3 · 2022: 1 · 2021: 8 · 2020: 5 · 2019: 4 · 2018: 4 · 2017: 10 · 2016: 8 · 2015: 3 · 2014: 7 · 2013: 5 · 2012: 4
- FWCI
- 6.81
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Translational research (publishedVersion)
- PubMed (publishedVersion)
- Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion)
- VU Research Portal (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Digital Academic REpository of VU University Amsterdam (Vrije Universiteit Amsterdam) (submittedVersion)
- Figshare (submittedVersion, cc-by)
- Pure Amsterdam UMC (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Funders
- National Institute of Mental Health (R01MH090035, K08MH072918)
- Topics
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- adolescent depression, depression prevention, motivational interviewing, brief advice, primary care physicians, online intervention, cognitive-behavioral training, interpersonal training, coming of age, depressive symptoms, hopelessness, depressive episodes, ease of use, predictors of treatment outcome
- MeSH terms
- Adolescent, Psychology, Adolescent, Attitude to Health, Depressive Disorder, Female, Humans, Interviews as Topic, Male, Motivation, Physicians, Predictive Value of Tests, Primary Health Care, Suicide, Attempted, Adolescent Health Services, Treatment Outcome, Internet
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