152. Prophylactic actions of Medhya rasayana drug – Shankhapushpi (Convolvulus pluricaulis Chois) on Drosophila (common fruit fly) model of Alzheimer's diseases
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disease (CVD) three-to fourfold, after accounting for sex, substance use, and depression while risk of cardiac mortality is increased twofold.Here, we examine the impact of the anxiety disorders on a psycho-physiological marker of health and well-being, heart rate variability (HRV).Previous studies are characterized by contradictory reports, highlighting the comprehensive approaches in clinical treatment.Cardiovascular disease (CVD) can be controlled through the sattvavajaya (Ay.psychotherapy),Satavavajaya is that method of treatment through which one tries to bring intellect (dhi.)fortitude (dhriti) and memory (smriti) of the patient to the optimum state.Eye movement desensitization and reprocessing technique (EMDR) can be a prototype of satvavajaya chikitsa as it attempts to install positive and wholesome memories (smriti) in to patient and remove (delete) the negative (unwholesome) thoughts by using sensory modalities like visual (eye movement) and auditory senses.Eye Movement desensitization and reprocessing (EMDR) therapy is an integrative psychotherapy approach that has been extensively researched and proven effective for the treatment of trauma and blocked/negative memories (unwholesome).It is a set of standardized protocols that incorporates elements from different treatment approaches.EMDR therapy also helps to treat many types of psychological stress, related with psychosomatic reactive depression, PTSD, OCD, panic anxiety disorder like IBS ,CAD,CVD, etc. Hypertension with apparent stressor based strictly on the principle of sattvavajaya chikitsa.OA14 147.
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Prophylactic consumption of Shankhapushpi reduces neurodegenerative symptoms in Drosophila melanogaster Alzheimer's disease model.
“Therefore, the study was conducted to assess how Shankhapushpi feeding affects the Drosophila melanogaster (common fruit fly) model of AD, and the findings suggested that prophylactic consumption of Shankhapushpi reduced the neurodegenerative symptoms seen in the Drosophila melanogaster AD model [140].”
From Unlocking the Therapeutic Potential of Medicinal Plants for Alzheimer’s Disease: Preclinical to Clinical Trial Insights (2023) · cites this paper as [140]
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Nagori, K., Nakhate, K. T., Yadav, K., Ajazuddin, & Pradhan, M. (2023) · Future Pharmacology · doi:10.3390/futurepharmacol3040053 · Cited by 61 · see citing works
- Authors
- Upadhyaya, W.
- Corresponding author
- Upadhyaya, Wasuki
- Venue
- Journal of Ayurveda and Integrative Medicine
- Publisher
- Elsevier BV
- Published
- 2018-04
- Volume
- 9
- Issue
- 2
- Pages
- S4
- ISSN
- 0975-9476 (ISSN-L)
- OpenAlex
- W2883618036
- Cited by
- 1
- References
- 0
- Citations by year
- 2023: 1
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Journal of Ayurveda and Integrative Medicine (publishedVersion, cc-by-nc-nd)
- Topics
- Health Sciences › Medicine › Complementary and alternative medicine › Medicinal Plants and Neuroprotection
- Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
- Health Sciences › Medicine › Complementary and alternative medicine › Phytochemicals and Medicinal Plants
- Keywords
- Convolvulus pluricaulis, Medhya Rasayana, Alzheimer's disease, Drosophila model, neuroprotection, Ayurveda, EMDR, anxiety disorders, heart rate variability, cardiovascular disease
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