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The Prevalence of Severe Asthma and Low Asthma Control Among Danish Adults
Abstract
Background The prevalence of severe asthma is unknown. However, international expert statements estimate that severe asthma represents 5% to 10 % of the entire asthma population.Objective Based on register data from a nationwide population, we wanted to investigate the prevalence of severe asthma, the extent of asthma control, and contact with specialist care.Methods A descriptive cross-sectional register study was performed. By using a nationwide prescription database, we identified current patients with asthma (age, 18-44 years) in 2010. Severity was classified as severe versus mild-moderate asthma according to the level of antiasthma treatment. We investigated prescription drug use, hospitalizations, emergency department visits, and outpatient clinic visits according to severity.Results Among a nationwide population, we identified 61,583 current patients with asthma. Based on the level of antiasthma treatment, 8.1% of identified patients was classified as having severe asthma. Low asthma control (dispensed prescriptions of prednisolone, emergency department visits, hospitalization, or excessive short-acting β₂-agonist use) was more frequent in subjects with severe asthma (36.4% vs 25.2%, P < .0001); 63.8% with severe asthma and low asthma control were not managed by specialist care. Patients with severe asthma with specialist contact more frequently had impaired asthma control compared with subjects not treated by a specialist (44.4% vs 33.1%, P < .0001).Conclusion Based on the level of treatment, 8.1% of a nationwide population of current patients with asthma was classified as having severe asthma. Low asthma control was more frequent among subjects with severe asthma, and only a minority had access to specialist care. There is room for optimizing asthma management, particularly among patients with severe disease.
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“Surveys in Denmark described a higher proportion of ~8% of severe asthmatics (37)”
From Epidemiology of Asthma in Children and Adults (2019) · cites this paper as [37]
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Metadata
- Authors
- von Bülow, A., Kriegbaum, M., Backer, V., & Porsbjerg, C.
- Affiliations
- University of Copenhagen (DK)
- Bispebjerg Hospital (DK)
- Venue
- The Journal of Allergy and Clinical Immunology In Practice
- Publisher
- Elsevier BV
- Published
- 2014-11
- Volume
- 2
- Issue
- 6
- Pages
- 759-767.e2
- ISSN
- 2213-2198 (ISSN-L)
- OpenAlex
- W2019613010
- Cited by
- 154
- References
- 50
- Citations by year
- 2026: 3 · 2025: 11 · 2024: 7 · 2023: 14 · 2022: 21 · 2021: 14 · 2020: 23 · 2019: 20 · 2018: 18 · 2017: 14 · 2016: 5 · 2015: 4
- FWCI
- 5.10
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Allergy and Clinical Immunology In Practice (publishedVersion)
- PubMed (publishedVersion)
- Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Occupational exposure and asthma
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Keywords
- severe asthma, asthma prevalence, asthma control, specialist care, hospitalization, emergency department visits, adults, Denmark
- MeSH terms
- Adolescent, Adult, Age Factors, Ambulatory Care, Asthma, Cross-Sectional Studies, Denmark, Emergency Service, Hospital, Female, Health Resources, Hospitalization, Humans, Lung, Male, Drug Prescriptions, Referral and Consultation, Registries, Severity of Illness Index, Prevalence, Treatment Outcome, Drug Utilization Review, Anti-Asthmatic Agents, Health Care Surveys, Young Adult
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